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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Advanced Herbal Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Stroke,Frankincense,Movement disorder,Speech disorder
- چکیده:
- چکیده انگلیسی: Background and aims: Ischemic stroke is the most common type of stroke and its most important symptoms are paralysis and movement disorders. Therefore, finding a method for treating this disorder is greatly important. This study was conducted to investigate the clinical efficacy of frankincense on the patients with ischemic stroke. Methods: In this clinical trial study, 60 patients with ischemic stroke were randomly assigned into two groups of treatment and control (30 patients in each group). In the treatment group, in addition to the routine treatment of stroke, four capsules containing 500 mg of powdered frankincense were used daily, but in the control group, only the treatment of stroke (without frankincense) was implemented. Treatment continued for one month. NIHSS questionnaire (to assess speech and muscle strength) was completed at the baseline, on the seventh day and at the end of treatment for each patient. In this study, statistical analysis was carried out by t- test, chi-square and Mann-Whitney using SPSS software. Results: The results showed that only in the second step in the treatment group, the rate of recovery of the left lower and muscle strength of upper limbs was significantly increased in patients compared to the control group. Conclusion: Introducing frankincense into treatment for stroke patients can contribute in improving muscle strength of the patients with muscle weakness in non-dominant hemisphere in acute phase of neurological disorder, while it has no effect improvement of muscle strength of right limbs or speech.
- انتشار مقاله: 09-12-1393
- نویسندگان: Nahid Jivad,Mahmoud Rafieian-Kopaei,Fakhri Rezaei-Kheirabadi,Shamsali Khosravi,Mahmoud Azizi
- مشاهده
- جایگاه : پژوهشی
- مجله: Advanced Herbal Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Honey,Alzheimer\'S Disease,Cyperus rotundus,Crocus sativus
- چکیده:
- چکیده انگلیسی: Background and aims: Alzheimer's disease is a progressive disorder of nervous system that leads to dementia in patients. This study was conducted to determine the effect of combination of honey, saffron (Crocus sativus L.) and sedge (Cyperus rotundus L.) on cognitive dysfunction in patients with Alzheimer’s disease. Methods: This double-blinded clinical trial study enrolling a sample size of 30 subjects was conducted per cross-over method. The patients with mild Alzheimer's disease obtaining the scores 12 ≥ in cog-ADAS scale were enrolled into the study. The participants were randomly assigned into two groups of A and B. During the first 2 months in group A, placebo was given, and group B underwent treatment with the combination under study. After a one-month period of washout, the same procedure was run reversely in two groups. Finally, the data analysis was done by SPSS software using descriptive and analytical tests. Result: Mann-Whitney test indicated no difference in mean cognitive dysfunction between two groups in neither of periods (P>0.05). Also, Friedman test showed no change in cognitive dysfunction during the study in neither of groups (group A: P=0.287, group B: P=0.158). Conclusion: Simultaneous use of honey, C. rotundus and C. sativus has no more pronounced effect than placebo on cognitive dysfunction in patients with mild to moderate Alzheimer's disease. It is recommended that future studies of this compound be done on patients of younger age and its preventive effects be addressed.
- انتشار مقاله: 16-11-1393
- نویسندگان: Nahid Jivad,Nadereh Zare-Hassanabadi,Mahmoud Azizi
- مشاهده