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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: children,Vitamin D deficiency,Metabolic Syndrome,25-hydroxyvitamin D
- چکیده:
- چکیده انگلیسی: Background: Metabolic syndrome (MS) is an important risk factor that is associated with vitamin D deficiency, according to recent studies. This study aimed to evaluate the relationship between serum 25-hydroxyvitamin D level and risk of metabolic syndrome in children in Birjand.
Materials and Methods: A case-control study on 6 to 18 years old metabolic syndrome patients, this investigation was performed in Birjand University of Medical Sciences, Cardiovascular Research Center. Thirty six children were enrolled in a non-random sampling manner, and the data were analyzed using SPSS-13 using independent t-test and chi square.
Results: A total of 36 children entered the study (n=18 per group). The mean serum levels of vitamin D in metabolic and non-metabolic groups was 11.61±3.79 and 14.09±6.41 ng/ml (P>0.05), respectively. The mean serum levels of vitamin D in the group with normal and abnormal triglyceride levels were 11.05±3.80 and 14.65±6.12 ng/ml, respectively (P<0.05).
Conclusion: The prevalence of vitamin D deficiency and insufficiency among children was high. Also, no association was found between vitamin D deficiency and metabolic syndrom. Controlled longitudinal studies are needed to better define the relationship between vitamin D status and pediatric metabolic syndrome.- انتشار مقاله: 25-01-1395
- نویسندگان: Mahmood Zardast,Fatemeh Taheri,Ahmad Gholinejadan,Kokab Namakin,Seyedailreza Javadinia
- مشاهده
- جایگاه : پژوهشی
- مجله: Addiction and Health
- نوع مقاله: Journal Article
- کلمات کلیدی: Addiction,homocysteine,fibrinogen,PROTHROMBIN TIME,PARTIAL THROMBOPLASTIN TIME,International normalized ratio,C-reactive protein
- چکیده:
- چکیده انگلیسی: Background: Regarding the limited studies about effects of addiction on coagulation factors as a risk factor for increasing coagulation, and its relation to coronary artery disease, we decided to investigate the effect of opium on inflammatory and coagulation factors in a controlled setting.Methods: This case-control study was performed using two groups of smoking males addicted to opium (27 cases) and not addicted to opium (27 cases). After collecting demographic data, venous blood samples were gathered and sent to laboratory for measuring homocysteine, fibrinogen, prothrombin time (PT), partial thromboplastin time (PTT), International Normalized Ratio (INR), and C-reactive protein (CRP) quantity. In order to analyze the data, we used independent t-test plus Mann-Whitney test with significance level of P < 0.05.Findings: The average age in this study was 32.2 ± 6.2 in case group and 33.3 ± 6.2 in control group. Comparing case and control groups regarding age and education showed no significant difference (P = 0.598 and P = 0.848, respectively). Mean daily smoking in case group was 7.9 ± 5.4 and 8.1 ± 5.0 in control group. Mean smoking duration in case group and control group was 10.1 ± 6.5 and 9.0 ± 7.2 years, respectively. There was no significant difference between two groups regarding smoking duration (P = 0.567). Comparison of inflammatory and coagulation factors showed no significant difference except for CRP and fibrinogen for which P = 0.661 and P = 0.889, respectively. Consumption-based comparison of inflammatory and coagulation factors showed no significant difference except for PT in oral and inhaled consumptions which showed a significant difference (P = 0.035).Conclusion: Results of this study suggest that opium addiction can be an influential factor in blood parameters and can lead to inflammatory and coagulation processes complications.
- انتشار مقاله: 17-07-1395
- نویسندگان: Nahid Azdaki,Mahmood Zardast,Gholamreza Anani-Sarab,Hamid Abdorrazaghnaejad,Mohammad Reza Ghasemian,Amin Saburi
- مشاهده