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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Journal of Dentistry, Shiraz University of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی: Regional odontodysplasia is a rare dental anomaly affecting both primary and adult dentitions in the maxilla or mandible or both jaws, whilst involvement of the maxilla is more common [1-2]. In most cases, one quadrant is affected. One of the characteristics of this anomaly is discolored and soft teeth that can be accompanied by swelling or abscess. In this anomaly, enamel and dentin are thin and hypoplastic, therefore, the teeth give the impression of “ghost teeth” [2, 8]. In radiography, the delineation between enamel and dentin is not clear and pulp chamber is wide. Histologically, areas of hypocalcified enamel are observed and the enamel prisms appear to be irregular in direction [2]. There is a disturbance in dentin formation and dentinal tubules are reduced in number. The etiology of regional odontodysplasia is still unknown [8]. Managements of these cases should be based on the esthetics and functional needs as well as the degree of involvement.This report describes a case of regional odontodysplasia in a 3.5 year old Iranian girl whose chief complaint was the abscess formation in the left maxillary primary molar region. This case study aims to report the clinical and radiological findings of the current case.
- انتشار مقاله: 07-08-1392
- نویسندگان: A. Rashidian,M. Afsharian Zadeh,M. Azarshab,T. Zarrabian
- مشاهده
- جایگاه : پژوهشی
- مجله: Archives of Razi Institute
- نوع مقاله: Journal Article
- کلمات کلیدی: Clostridium septicum,Vaccine media,Alpha toxin,Growth,magnesium
- چکیده:
- چکیده انگلیسی: Clostridium septicum, the anaerobic toxigenic bacterium is the agent that causes dangerous disease in man and animals. There is a lethal toxin of the bacterium namely alpha toxin. The ɑ-toxin has hemolytic, necrotic and lethal activities. Today, Razi Vaccine and Serum Research Institute of Iran produced the C. septicum vaccine in the form of bacterin/toxoid. Because of some problems, the vaccine needs to improve on an industrial scale. The study is going to find an appropriate supplement to improve growth and ɑ-toxin production. Three strains of C. septicum (vaccine, NH1 and NH8 strains) were cultured in the basic vaccine media. Magnesium sulfate, Copper, Ferrous, yeast extract, and trace elements plus vitamins' solution were added to the basic vaccine media in different cultures. The effect of the ingredients on the growth was measured by a spectrophotometer and the α-toxin secretion was assayed by hemolysin test. Growth of the bacterium and α-toxin secretion were increased by Magnesium (80 mg/l) in NH8 and vaccine strains significantly. The black precipitate was difficult to dissolve in magnesium media that must be solved. Trace elements plus vitamins solution mildly influence on NH1strain growth and toxin secretion. Other supplements (Cu, Fe, yeast extract) were not showen any significant changes in the growth and α-toxin production of C. septicum. Overflowing peptone (4%) in the vaccine media, fixes essentials of proteolysis activity, allows the sufficient growth and toxin production without Cu, Fe, and yeast extract. Due to essentially of Mg for growth, extra magnesium was added for improvement of media culture. The study suggests for Magnesium addition in the C. septicum vaccine media during production procedure after precipitation solving problem.
- انتشار مقاله: 04-10-1397
- نویسندگان: M. Fathi Najafi,M. Hemmaty,J. Navidmehr,M. Afsharian,M. Farhoodi,S. Zibaee
- مشاهده