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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Low back pain,Lymphangioma,Retroperitoneum
- چکیده:
- چکیده انگلیسی:
Abdominal cystic lymphangioma is a rare benign neoplasm. Less than 1% of lymphangiomas is in the retroperitoneum. Lymphangioma is mostly asymptomatic. Chronic symptoms were reported in retroperitoneal type more than others. Acute symptoms due to complications like infection, cyst rupture or hemorrhage may occur. We report an 18-years-old girl with low back pain from 6 months ago with huge pelvic mass and diagnosis of retroperitoneal cystic lymphangioma.- انتشار مقاله: 02-11-1392
- نویسندگان: Asieh Sadat Fattahi,Godratollah Maddah,Mohammad Motamedolshariati,Taghi Ghiasi–Moghadam
- مشاهده
- جایگاه : پژوهشی
- مجله: World Sociopolitical Studies
- نوع مقاله: Journal Article
- کلمات کلیدی: Iran,Diplomacy,sport,peace,Fuzzy Delphi Method
- چکیده:
- چکیده انگلیسی: The purpose of this study is to identify the role of sport as a soft power for Iran to facilitate its diplomatic relations after the nuclear deal. The research method used in this study is mixed (qualitative and quantitative): in the qualitative part of the analysis, the study sample was selected via Snowball sampling based on partricipants’ expertise in the sport diplomacy of Iran after two rounds of Fuzzy Delphi Method (FDM) exploratory factor analysis. Seven components of political currents, cultural exchange, peacemaking, national unity, economic development, transformation, communication, and religious currents were extracted. After identifying the study’s research variables in a structural-interpretive modeling, the relationship between variables was examined through a structural equation modeling test. The results of the structural equation model indicated that political currents, cultural exchange, transformation and communication had a direct and significant effect on national unity. The relationship between political and peacebuilding was not confirmed, but national unity and excellence in peace diplomacy had a direct and significant impact on the economic development of societies.
- انتشار مقاله: 23-07-1397
- نویسندگان: Arash Dousti,Reza Saboonchi,Mahdi Shariati Feizabadi
- مشاهده
- جایگاه : پژوهشی
- مجله: Nanomedicine Journal
- نوع مقاله: Journal Article
- کلمات کلیدی: Memory,Royal jelly,Hippocampus,TRPV1,Silver-nanoparticles
- چکیده:
- چکیده انگلیسی: Objective (s): Silver nanoparticles (NPs) have attracted considerable attention owing to their important properties, including antimicrobial and anti-oxidative stress effects. However, high concentrations of silver NPs have been reported to have toxic effects. The present study aimed to evaluate the modulatory and protective effects of royal jelly (RJ) against the harmful effects of silver NPs on hippocampal functions, such as learning and memory.
Materials and Methods: This experimental study was conducted on 40 male Wistar rats. The animals were divided into four groups of 10, including the control group (no silver NPs and RJ), RJ group, silver NPs plus RJ, and silver NPs. Some functions of the hippocampus (e.g., learning and memory) were evaluated using Morris memory function tests for four consecutive days. In addition, the relative expression of TRPV1 was assessed using real-time polymerase chain reaction (RT-PCR). At the final stage, hippocampal tissues were collected for histological studies.
Results: Levels of learning and memory, relative gene expression ratio of TRPV1, and the histological changes in the hippocampus were significantly different in the groups receiving silver NPs compared to the groups administered with RJ.
Conclusion: According to the results, RJ may be the effective in the protection against the adverse effects of silver NPs and improve the function of the hippocampus.- انتشار مقاله: 29-11-1397
- نویسندگان: Mahsa Dalfardi,Mohammad Mohsen Taghavi,Mahdi Shariati Kohbanani,Zahra Taghipour,Reza Nosratabadi,Cyrus Jalili,Mohammad Reza Salahshoor,Ayat Kaeidi,Ahmad Shabanizadeh
- مشاهده
- جایگاه : پژوهشی
- مجله: Nanomedicine Journal
- نوع مقاله: Journal Article
- کلمات کلیدی: Memory,Royal jelly,Hippocampus,TRPV1,Silver-nanoparticles
- چکیده:
- چکیده انگلیسی: Objective (s): Silver nanoparticles (NPs) have attracted considerable attention owing to their important properties, including antimicrobial and anti-oxidative stress effects. However, high concentrations of silver NPs have been reported to have toxic effects. The present study aimed to evaluate the modulatory and protective effects of royal jelly (RJ) against the harmful effects of silver NPs on hippocampal functions, such as learning and memory.
Materials and Methods: This experimental study was conducted on 40 male Wistar rats. The animals were divided into four groups of 10, including the control group (no silver NPs and RJ), RJ group, silver NPs plus RJ, and silver NPs. Some functions of the hippocampus (e.g., learning and memory) were evaluated using Morris memory function tests for four consecutive days. In addition, the relative expression of TRPV1 was assessed using real-time polymerase chain reaction (RT-PCR). At the final stage, hippocampal tissues were collected for histological studies.
Results: Levels of learning and memory, relative gene expression ratio of TRPV1, and the histological changes in the hippocampus were significantly different in the groups receiving silver NPs compared to the groups administered with RJ.
Conclusion: According to the results, RJ may be the effective in the protection against the adverse effects of silver NPs and improve the function of the hippocampus.- انتشار مقاله: 29-11-1397
- نویسندگان: Mahsa Dalfardi,Mohammad Mohsen Taghavi,Mahdi Shariati Kohbanani,Zahra Taghipour,Reza Nosratabadi,Cyrus Jalili,Mohammad Reza Salahshoor,Ayat Kaeidi,Ahmad Shabanizadeh
- مشاهده
- جایگاه : پژوهشی
- مجله: Progress in Biological Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: cancer,Curcumin,Nanotechnology,Dendrosomal curcumin,Dendrosome
- چکیده:
- چکیده انگلیسی: Curcumin is a hydrophobic polyphenol extracted from the plant curcuma longa with established
anticancer properties. However, curcumin benefits have been impaired by its very low water
solubility, low absorption, rapid metabolism and clearance from the body. Recently,
nanotechnology promises to be helpful in development of drugs delivery systems by recent
advances in macromolecular design of nanocarriers. In this review, we present the novel
generation of nano-vehicles termed dendrosomes which are readily synthesized from
esterification of oleic acid and polyethylene glycol residues. Dendrosomes efficiently
encapsulate curcumin in a spherical micellar or polymersome structures which leads to increase
aqueous solubility of this hydrophobic agent and higher bioavailability of curcumin. Anticancer
potency of this nanoformulation was confirmed in different mouse and human cancer
cells including fibrosarcoma, colon, glioblastoma, bladder, gastric, breast and hepatocellular
carcinoma in vitro and vivo. It has also demonstrated that this nano preparation has no
cytotoxicity effects on normal cells. Finally, these results introduce dendrosomal curcumin as
potent anti-tumor agent although further clinical examinations are needed.- انتشار مقاله: 10-12-1393
- نویسندگان: Maryam Tahmasebi Birgani,Vahid Erfani-Moghadam,Esmail Babaei,Farhood Najafi,Mina Zamani,Molood Shariati,Shima Nazem,Baharak Farhangi,Paria Motahari,Majid Sadeghizadeh
- مشاهده
- جایگاه : پژوهشی
- مجله: Progress in Biological Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: cancer,Curcumin,Nanotechnology,Dendrosomal curcumin,Dendrosome
- چکیده:
- چکیده انگلیسی: Curcumin is a hydrophobic polyphenol extracted from the plant curcuma longa with established
anticancer properties. However, curcumin benefits have been impaired by its very low water
solubility, low absorption, rapid metabolism and clearance from the body. Recently,
nanotechnology promises to be helpful in development of drugs delivery systems by recent
advances in macromolecular design of nanocarriers. In this review, we present the novel
generation of nano-vehicles termed dendrosomes which are readily synthesized from
esterification of oleic acid and polyethylene glycol residues. Dendrosomes efficiently
encapsulate curcumin in a spherical micellar or polymersome structures which leads to increase
aqueous solubility of this hydrophobic agent and higher bioavailability of curcumin. Anticancer
potency of this nanoformulation was confirmed in different mouse and human cancer
cells including fibrosarcoma, colon, glioblastoma, bladder, gastric, breast and hepatocellular
carcinoma in vitro and vivo. It has also demonstrated that this nano preparation has no
cytotoxicity effects on normal cells. Finally, these results introduce dendrosomal curcumin as
potent anti-tumor agent although further clinical examinations are needed.- انتشار مقاله: 10-12-1393
- نویسندگان: Maryam Tahmasebi Birgani,Vahid Erfani-Moghadam,Esmail Babaei,Farhood Najafi,Mina Zamani,Molood Shariati,Shima Nazem,Baharak Farhangi,Paria Motahari,Majid Sadeghizadeh
- مشاهده
- جایگاه : پژوهشی
- مجله: Progress in Biological Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: cancer,Curcumin,Nanotechnology,Dendrosomal curcumin,Dendrosome
- چکیده:
- چکیده انگلیسی: Curcumin is a hydrophobic polyphenol extracted from the plant curcuma longa with established
anticancer properties. However, curcumin benefits have been impaired by its very low water
solubility, low absorption, rapid metabolism and clearance from the body. Recently,
nanotechnology promises to be helpful in development of drugs delivery systems by recent
advances in macromolecular design of nanocarriers. In this review, we present the novel
generation of nano-vehicles termed dendrosomes which are readily synthesized from
esterification of oleic acid and polyethylene glycol residues. Dendrosomes efficiently
encapsulate curcumin in a spherical micellar or polymersome structures which leads to increase
aqueous solubility of this hydrophobic agent and higher bioavailability of curcumin. Anticancer
potency of this nanoformulation was confirmed in different mouse and human cancer
cells including fibrosarcoma, colon, glioblastoma, bladder, gastric, breast and hepatocellular
carcinoma in vitro and vivo. It has also demonstrated that this nano preparation has no
cytotoxicity effects on normal cells. Finally, these results introduce dendrosomal curcumin as
potent anti-tumor agent although further clinical examinations are needed.- انتشار مقاله: 10-12-1393
- نویسندگان: Maryam Tahmasebi Birgani,Vahid Erfani-Moghadam,Esmail Babaei,Farhood Najafi,Mina Zamani,Molood Shariati,Shima Nazem,Baharak Farhangi,Paria Motahari,Majid Sadeghizadeh
- مشاهده
- جایگاه : پژوهشی
- مجله: Progress in Biological Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Dunaliella tertiolecta,biomass limitation,cell density,intrinsic behavior Media condition
- چکیده:
- چکیده انگلیسی: Microalgal growth curve, after the exponential phase, shows a stationary phase where algal
biomass production is inhibited and remains constant by some factors such as nutrient
depletion and intrinsic behavior. The present study is concerned with evaluating effects of
the culture medium condition and intrinsic behavior on biomass production by Dunaliella
tertiolecta. To this end, effect of pH, nutrient concentration, CO2 (NaHCO3) concentration,
possible secreted substances, and cell density on the biomass production by D. tertiolecta
were investigated. The results showed that biomass yield can be significantly affected by pH
(p<0.01) and nutrient (p<0.05). In a combination of pH and nutrient, the biomass was found to
be more influenced by the pH, compared with the nutrients. The results showed a significant
interaction between nutrient and NaHCO3 (p<0.05), suggesting that CO2 concentration may
limit biomass production only when sufficient nutrients are available. Nutrients concentration
and biomass production showed a direct correlation (p<0.05). The rate of reaching the
maximum biomass was showed to be increased in higher nutrients concentration; however,
the maximum point could not to be affected. The existence of secreted compounds with
inhibitory effect on the growth was not observed. The inhibitory effect of the cell density on
biomass production can not be confirmed.- انتشار مقاله: 25-02-1392
- نویسندگان: Reza Taheri,Mansour Shariati
- مشاهده
- جایگاه : پژوهشی
- مجله: Progress in Biological Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: cancer,Curcumin,Nanotechnology,Dendrosomal curcumin,Dendrosome
- چکیده:
- چکیده انگلیسی: Curcumin is a hydrophobic polyphenol extracted from the plant curcuma longa with established
anticancer properties. However, curcumin benefits have been impaired by its very low water
solubility, low absorption, rapid metabolism and clearance from the body. Recently,
nanotechnology promises to be helpful in development of drugs delivery systems by recent
advances in macromolecular design of nanocarriers. In this review, we present the novel
generation of nano-vehicles termed dendrosomes which are readily synthesized from
esterification of oleic acid and polyethylene glycol residues. Dendrosomes efficiently
encapsulate curcumin in a spherical micellar or polymersome structures which leads to increase
aqueous solubility of this hydrophobic agent and higher bioavailability of curcumin. Anticancer
potency of this nanoformulation was confirmed in different mouse and human cancer
cells including fibrosarcoma, colon, glioblastoma, bladder, gastric, breast and hepatocellular
carcinoma in vitro and vivo. It has also demonstrated that this nano preparation has no
cytotoxicity effects on normal cells. Finally, these results introduce dendrosomal curcumin as
potent anti-tumor agent although further clinical examinations are needed.- انتشار مقاله: 10-12-1393
- نویسندگان: Maryam Tahmasebi Birgani,Vahid Erfani-Moghadam,Esmail Babaei,Farhood Najafi,Mina Zamani,Molood Shariati,Shima Nazem,Baharak Farhangi,Paria Motahari,Majid Sadeghizadeh
- مشاهده
- جایگاه : پژوهشی
- مجله: Progress in Biological Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Dunaliella tertiolecta,biomass limitation,cell density,intrinsic behavior Media condition
- چکیده:
- چکیده انگلیسی: Microalgal growth curve, after the exponential phase, shows a stationary phase where algal
biomass production is inhibited and remains constant by some factors such as nutrient
depletion and intrinsic behavior. The present study is concerned with evaluating effects of
the culture medium condition and intrinsic behavior on biomass production by Dunaliella
tertiolecta. To this end, effect of pH, nutrient concentration, CO2 (NaHCO3) concentration,
possible secreted substances, and cell density on the biomass production by D. tertiolecta
were investigated. The results showed that biomass yield can be significantly affected by pH
(p<0.01) and nutrient (p<0.05). In a combination of pH and nutrient, the biomass was found to
be more influenced by the pH, compared with the nutrients. The results showed a significant
interaction between nutrient and NaHCO3 (p<0.05), suggesting that CO2 concentration may
limit biomass production only when sufficient nutrients are available. Nutrients concentration
and biomass production showed a direct correlation (p<0.05). The rate of reaching the
maximum biomass was showed to be increased in higher nutrients concentration; however,
the maximum point could not to be affected. The existence of secreted compounds with
inhibitory effect on the growth was not observed. The inhibitory effect of the cell density on
biomass production can not be confirmed.- انتشار مقاله: 25-02-1392
- نویسندگان: Reza Taheri,Mansour Shariati
- مشاهده