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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Quality of Life,head and neck cancer,induction chemotherapy,Swallow
- چکیده:
- چکیده انگلیسی: Objective: To evaluate the effect of induction chemotherapy on swallowing and swallowing-related quality of life
of patients with oropharyngeal, laryngeal and hypopharyngeal cancer. Study design: Prospective study of 33 patients
with locally advanced tumors who were eligible for treatment with neoadjuvant chemotherapy followed by radiotherapy
and concurrent chemotherapy. A multidimensional assessment of swallowing was performed using the following
tools: (1) Clinical analysis, numerical scale for general pain and painful swallowing, American Speech and Hearing
Association (ASHA) Functional Communication Measures (FCM) swallowing assessment scales, (2) assessment
of Swallowing-Related Quality of Life (The MD Anderson Dysphagia Inventory - MDADI), and (3) swallowing
videofluoroscopy. Results: There was a reduction in general pain scale (p=0.021), and quality of life (emotional,
functional and physical) improved from average limitation (score of 61-80) to minimal limitation (81-100) after
induction chemotherapy. According to the swallowing videofluoroscopy results, 26 (78.7%) of the patients had some
degree of dysphagia pre-treatment, which decreased to 21 (63.6%) after induction. Conclusion: Our results suggest
that induction chemotherapy improves numerous aspects of swallowing and has a positive impact on the quality of
life of pre-chemoradiotherapy patients.- انتشار مقاله: 22-01-1397
- نویسندگان: Juliana Portas,Daniela Corrêa,Débora Queija,Lidia Maria Rebolho Batista Arantes,Luciano De Souza Viana,André Lopes Carvalho
- مشاهده