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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی: Carbon Monoxide,Methylene Chloride,Subcutaneous Injection
- چکیده:
- چکیده انگلیسی: Background: Dichloromethane (a chlorinated hydrocarbon) is normally used as a solvent. Dichloromethane poisoning has been reported from occupational exposure and the common routes of dichloromethane poisoning are ingestion and inhalation.
Case presentation: We described a case of 51-year-old man who received subcutaneous injection of dichloromethane and presented with local wound necrosis at his forearm, but carboxyhemoglobin levels were normal.
Discussion: The corrosive property of dichloromethane result in venous thrombosis formation at his wound that might prevent systemic absorption of dichloromethane leads to reduced hepatic converted dichloromethane to the carbon monoxide.
Conclusion: Symptomatic treatment and monitoring of CO production remain the mainstay in the treatment of patients with subcutaneous injection of dichloromethane.- انتشار مقاله: 24-03-1397
- نویسندگان: Kitisak Sanprasert,Thunyaporn Tangtrongchitr,Nat Krairojananan
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی: Jatropha Curcas,Saboo Dum,Thailand
- چکیده:
- چکیده انگلیسی: Background: Jatropha curcas,commonly known as “Saboo Dum,” is the most common plant poisoning in Thailand. Saboo Dum seeds are used as raw material for biodiesel fuel manufacture, especially in Royal Thai Military units. The seed contains a toxin called curcin which can cause hepatotoxicity in humans.
Case Presentation: We reported twenty-eight private soldiers who were brought to the emergency department with gastrointestinal symptoms after having been ingested Saboo Dum. Four patients had mild elevated liver function test (56.25±7.38). In our case series, gastrointestinal symptoms were predominant symptoms (nausea and vomiting 96.4%, diarrhea 78.6% and abdominal pain 50%). All patients discharged from hospital without any complications.
Discussion:Curcin can cause hepatotoxicity similar to ricin but less potent than ricin which may explain the clinical manifestations in our patients.
Conclusion: As the lack of awareness of Saboo Dum poisoning is the major cause of intoxication, knowledge of this seed may play an important role in the reduced incidence of curcin poisoning.- انتشار مقاله: 07-12-1395
- نویسندگان: Thunyaporn Tangtrongchitr,Nat Krairojananan,Kitisak Sanprasert
- مشاهده