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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Ultrasound,Keywords: BI-RADS,probably benign,biopsy
- چکیده:
- چکیده انگلیسی: Objective: To determine the negative predictive value of ultrasound for breast masses with probably benign
morphology, and to assess whether follow-up may be an acceptable alternative to biopsy. Methods: After Institutional
Review Board approval, all solid breast masses categorized as probably benign (American College of Radiology Breast
Imaging Reporting and Data System [BI-RADS] 3) on ultrasound from January 2014 to December 2015, and having
either tissue diagnosis or imaging stability for 24 months, or downgrading to BIRADS 2 during imaging surveillance
were included. Result: A total of 157 lesions in 40 patients constituted the study population. The mean patient age was
31.3 years (range, 20-56 years). Seventeen of these 157 lesions underwent tissue diagnosis with no invasive breast cancer.
Out of the remaining 140 lesions, 115 were stable on imaging for 24 months or more. The rest 25 were deemed benign
because of decrease in size on follow up (n=1), non-recommendation of further imaging by the second radiologist on
follow up ultrasound (n= 13) or presence of benign tissue diagnosis in the largest lesion (n=11). Conclusion: Ultrasound
has 100% negative predictive value for breast lesions with probably benign morphology, whether palpable or not.
Follow up is an appropriate option to immediate biopsy of such lesions keeping in mind that noncompliance with
surveillance may be a potential problem.- انتشار مقاله: 24-11-1396
- نویسندگان: Kulsoom Fatima,Imrana Masroor,Samina Khanani
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Breast cancer,Mammogram,breast conservation,complete local excision,Specimen radiography
- چکیده:
- چکیده انگلیسی: Objective: The aim of this study was to evaluate the accuracy of “X- ray examination of surgically
resected specimen‘‘ in assessing complete local excision (CLE). Materials and Methods: In this retrospective cross
sectional study, data were collected for all female breast cancer cases who underwent breast-conserving surgery after
needle localization of mammographically visible disease. Males, patients with mammographically invisible disease
and cases with benign or inconclusive histopathology, those undergoing modified radical mastectomy and individuals
with dense breast parenchyma were excluded. We evaluated radiography of resected specimens to assess margin
spiculation, distance of mass/microcalcification from the excised margin, presence of a mass, and presence of any
adjacent microcalcification, Other features including mass size, nuclear grade and patient’s age were also recorded and
all were analyzed for any association with CLE. Results: Absence of adjacent microcalcification and the presence of a
mass on radiographs showed significant associations with CLE, but no links were evident with other features. Specimen
radiography was found to be a sufficient tool to predict CLE with a positive predictive value of 83.3%, a sensitivity of
80.7% and a specificity of 81%. Conclusion: Specimen radiography is an important and sensitive tool to predict CLE.- انتشار مقاله: 31-06-1396
- نویسندگان: Saira Naz,Imrana Masroor,Shaista Afzal,Wasim Mirza,Sehrish Butt,Zafar Sajjad,Anwar Ahmed
- مشاهده