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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Current Medical Mycology
- نوع مقاله: Journal Article
- کلمات کلیدی: Iran,dermatophytes,Onychomycosis,Tinea capitis
- چکیده:
- چکیده انگلیسی: Background and Purpose: Tinea capitis and tinea unguium are regarded as global public health concerns. The purpose of the present study was to identify the etiological agents of tinea capitis and tinea unguium in patients, referring to the Central Laboratory of Yazd University of Medical Sciences, Yazd, Iran.
Materials and Methods: This study was conducted during 2014-2015. Skin scraping, scalp hair, and nail clipping specimens were collected from 134 patients (80 males and 54 females) with clinical features suggesting fungal involvement. Direct microscopic examinations were carried out, using potassium hydroxide 10%, while culture studies were performed on Sabouraud dextrose agar, containing chloramphenicol and cycloheximide at 28°C for four weeks. Fungal colonies were identified based on their macroscopic and microscopic characteristics, as well as supplementary diagnostic tests.
Results: Among 134 patients, 12 cases showed positive results on direct examination and culture studies. The frequency of infections was equal among male and female subjects. Among 12 affected cases, the frequency of tinea capitis and tinea unguium was 91.6% and 8.4%, respectively. Microsporum canis (50%) was the most prevalent species, followed by Trichophyton verrucosum (25%) and Trichophyton mentagrophytes (25%). Also, tinea unguium, caused by T. mentagrophytes, was found in a female patient.
Conclusion: The etiological agents of scalp and nail dermatophytosis have changed in Yazd over the past 13 years. In the present study, replacement of anthropophilic dermatophytes by zoophilic species was noteworthy, highlighting the necessity of efficient surveillance for the management and prevention of infections.- انتشار مقاله: 18-04-1398
- نویسندگان: Hossein Sadeghi Tafti,Mehraban Falahati,Parivash Kordbacheh,Mahmoud Mahmoudi,Mahin Safara,Sara Rashidian,Shahram Mahmoudi,Farideh Zaini
- مشاهده
- جایگاه : پژوهشی
- مجله: Desert
- نوع مقاله: Journal Article
- کلمات کلیدی: Drought,Chlorophyll,Arid regions,ABA,root dry weight
- چکیده:
- چکیده انگلیسی: In order to investigate the effect of drought and salinity stress on caper plant (Capparis spinosa), a factorial experiment including two factors consisting of drought and salinity levels based on randomized complete block design (RCBD) with five blocks were carried out at College of Agriculture, Shiraz University, Shiraz, Iran. After pretreatment, seeds were germinated in petri dishes and then transported to pots, to grow out of the glasshouse under natural conditions (same as environmental condition). Measuring morphological (Plant height, number of leaves, length of greatest leaf, root length, shoot fresh weight, shoot dry weight, root fresh weight and root dry weight, and chlorophyll (pad) and also physiological traits (relative water content (RWC) and water saturated deficit (WSD) for both root and shoot, root water content (RooWC) and leaf water content (LWC) showed that salinity and drought stresses as well as ABA concentration had negative effects on the plant. ABA content was significantly higher in salt-treated plants than in drought treated ones. The injury effect of salt stress was lower than drought. The results also indicated that the changes in response to the two stresses were low and so that this plant could be a suitable candidate for sowing and using in arid and semi-arid regions and also in saline condition.
- انتشار مقاله: 27-05-1395
- نویسندگان: Hossein Sadeghi,Laleh Rostami
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Economic Studies
- نوع مقاله: Journal Article
- کلمات کلیدی: Iran,Medical tourism,Health Tourism,Structural Equations Modeling,Partial Least Squares
- چکیده:
- چکیده انگلیسی: Health tourism is a profitable and competitive industry, which includes both medical and wellness tourism. This research intends to identify and analyze the determinants of medical tourism expansion in Iran. To this end, first, 384 questionnaires were distributed among medical tourists visiting selected private hospitals in Tehran, and medical tourism experts in both private and public sectors in 2017. The data obtained from the questionnaires were analyzed using Structural Equation Modeling (SEM). The price level had the greatest impact on attracting the medical tourists in 2017. The service and therapeutic capacities, and the characteristics of the destination ranked second and third, respectively. Marketing and public sector policy-making had positive but relatively small effects on attracting medical tourists to Iran. To compete with rival countries in attracting medical tourists, surgical operations should be presented efficiently. Private hospitals have to maintain their equipment and technology at the same level as those in the advanced countries. Furthermore, public and private sectors should spend more on advertising and marketing. Finally, in attracting more medical tourists, the role of public policy should be considered seriously.
- انتشار مقاله: 20-06-1397
- نویسندگان: Mirhojjat NajafiNasab,Lotfali Agheli,Mônica Viegas Andrade,HOSSEIN SADEGHI,Sajjad Faraji Dizaji
- مشاهده
- جایگاه : پژوهشی
- مجله: Chemical Methodologies
- نوع مقاله: Journal Article
- کلمات کلیدی: Ionic Liquid,Folic acid analysis,Food analysis,Fruit Juices,Modified sensor
- چکیده:
- چکیده انگلیسی: Folic acid is an important food additive found in most food products. This research study focused on making a powerful analytical device to determine the folic acid concentration in food products. An electrochemical amplified sensor based on paste electrode (PE) modified with CuO-CNTs and 1-butyl-2,3-dimethylimidazolium hexafluorophosphate (BDHFP) was fabricated and used to study the electro-oxidation of folic acid. Oxidation current of folic acid was improved about 2.8 times at PE/M/CuO-CNTs/BDHFP compared with that of the PE. In addition, an irreversible and pH dependent oxidation signal was detected for redox reaction of folic acid at surface of PE/M/CuO-CNTs/BDHFP. Active surface area of PE was increased from 0.11 cm2 to 0.18 cm2 after modification with CuO-CNTs and BDHFP. Differential pulse voltammetric (DPV) signals displayed a linear dynamic range 3.0 nM–250 µM with detection limit 0.8 nM for measurement of folic acid. To study the ability of the PE/M/CuO-CNTs/BDHFP to determine the folic acid in real samples, apple and orange juices were selected and recovery data between 99.29%-101.6% confirm high performance ability of PE/M/CuO-CNTs/BDHFP for determination of folic acid in real samples.
- انتشار مقاله: 07-03-1399
- نویسندگان: Hossein Sadeghi,Seyed-Ahmad Shahidi,Shahram Naghizadeh Raeisi,Azade Ghorbani-HasanSaraei,Fateme Karimi
- مشاهده
- جایگاه : پژوهشی
- مجله: Avicenna Journal of Phytomedicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Rats,Hepatoprotective,Tetrachloride,Rosa canina fruit
- چکیده:
- چکیده انگلیسی: Objective: The present study was conducted to investigate the hepatoprotective activity of hydro-ethanolic fruit extract of Rosa canina (R. canina) against carbon tetrachloride (CCl4)-induced hepatotoxicity in rats.
Methods: Male Wistar albino rats were randomly divided into six groups of 8 animals of each, including control, toxic (CCl4), R. canina 250, 500, and 750 mg/kg + CCl4 and R. canina 750 mg/kg alone. R. canina (p.o., daily) and CCl4 (1 ml/kg twice a week, 50% v/v in olive oil, i.p.) were administered to animals for six weeks. Serum analysis was performed to assay the levels of aspartate aminotransferase (AST), alanine amino transaminase (ALT), alkaline phosphatase (ALP), albumin (ALB), total protein (TP) and malondialdehyde (MDA). Biochemical observations were also supplemented with histopathological examination (haematoxylin and eosin staining) of liver section.
Results: Hepatotoxicity was evidenced by considerable increase in serum levels of AST, ALT, ALP, and lipid peroxidation (MDA) and decrease in levels of ALB and TP. Injection of CCL4 also induced congestion in central vein, and lymphocyte infiltration. Treatment with hydro-alcoholic fruit extract of R. canina at doses of 500 and 750 mg/kg significantly reduced CCl4-elevated levels of ALT, AST, ALP and MDA (p<01). The extract also increased the serum levels of ALB and TP compared to CCl4 group (p<01) at the indicated dose Histopathological studies supported the biochemical finding.
Conclusion: our finding indicated hepatoprotective effects of the hydro-alcoholic fruit extract of R. canina on CCl4-induced hepatic damage in rats and suggested that theses effect may be produced through reducing oxidative stress.- انتشار مقاله: 23-07-1393
- نویسندگان: Heibatollah Sadeghi,Abdol Saleh Hosseinzadeh,Mehdi Akbartabar Touri,Mehdi Ghavamzadeh,Mehrzad Jafari Barmak,Hossein Sadeghi,Moslem Sayahi
- مشاهده
- جایگاه : پژوهشی
- مجله: Avicenna Journal of Phytomedicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Antioxidant property,Hepatoprotective effect,Otostegia persica,Liver injury,Carbon tetrachloride
- چکیده:
- چکیده انگلیسی: Objective: To evaluate the hepatoprotective properties of Otostegia persica (O. persica) ethanol extract on carbon tetrachloride-induced liver damage in rats.
Materials and Methods: Fifty adult male Wistar rats were randomly divided into five groups. Group I served as normal control and was given only olive oil intraperitoneally (i.p.). Group II, III, IV, and V were administered CCl4 mixed with olive oil 1:1 (1 ml/kg) i.p., twice a week for 8 weeks. Group II was maintained as CCl4-intoxicated control (hepatotoxic group). Group III, IV, and V received O. persica extract at a dose of 40, 80, and 120 mg/kg for 8 weeks every 48 h orally, respectively. Biochemical parameters including aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), total bilirubin (TB), albumin (ALB), total protein (TP), and lipid peroxidation marker (Malonaldialdehyde, (MDA) were determined in serum. After 8 weeks, animals were sacrificed, livers dissected out, and evaluated for histomorphological changes.
Results: The administration of CCl4 increased AST, ALT, ALP, TB, and MDA in serum but it decreased TP , and ALB compared with normal control. Treatment with O. persica extract at three doses resulted in decreased enzyme markers, bilirubin levels, and lipid peroxidation marker (MDA) and increased TP and ALB compared with CCl4 group. The results of pathological study also support the hepatoprotective effects which were observed at doses of 80 and 120 mg/kg.
Conclusion: The results of the present study indicate that ethanol extract of O. persica may have hepatoprotective effect which is probably due to its antioxidant property.- انتشار مقاله: 22-09-1392
- نویسندگان: Mehdi Akbartabar Toori,Behzad Joodi,Heibatollah Sadeghi,Hossein Sadeghi,Mehrzad Jafari,Mohammad Sharif Talebianpoor,Foad Mehraban,Mostafa Mostafazadeh,Mehdi Ghavamizadeh
- مشاهده