در هنگام جستجو کلمه در قسمت عنوان میتوانید کلمات مورد جستجو را با کاراکتر (-) جدا کنید.
کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Journal of Water and Environmental Nanotechnology
- نوع مقاله: Journal Article
- کلمات کلیدی: Magnetite nanoparticles,Propionibacterium freudenreichii,Cobalamins biosynthesis,RSM Optimization
- چکیده:
- چکیده انگلیسی: Cobalamins are one of the most complicated cofactors produced by the microorganisms. Propionibacterium freudenreichii has to follow the anaerobic and aerobic conditions respectively during a course of batch fermentation, for the production of the biologically active form of cobalamins. Magnetite (Fe3O4) nanoparticles can modify gas-liquid volumetric mass transfer coefficient in the fermentation system to create more efficient aeration step. Initially, the modified production of Fe3O4 nanoparticle through coprecipitation method was investigated, and the smallest size of nanoparticles optimized to 13.86 nm via Box-Behnken design of response to surface methodology (RSM). The optimum condition was at the synthesis temperature of 60 °C, reaction duration of 10 minutes, and the medium agitation speed of 700 rpm. Synthesized nanoparticles characterized by SEM images, PXRD and EDS analysis while EDS spectrum reflects 39.33% of Fe and 51.8% of oxygen atomic distribution, which confirms Fe3O4 nanoparticles synthesis. Magnetite nanoparticle suspension added to the fermentation medium to compare the effect of nanoparticles incorporation and dimethylbenzimidazole addition on the cobalamin production via Propionibacterium freudenreichii. NPs incorporation in the fermentation broth was able to increase cyanocobalamin production by 20%, while there was no incorporation of external DMBI in the medium. Finally, by the central composite design analysis, cyanocobalamin production from Propionibacterium freudenreichii fermentation was optimized to 1.548 mg.L-1. Oily sludge (as a new carbon source) of 4 %w/v, magnetite nanoparticles suspension of 7.5 %v/v, and the fermentation temperature of 37 °C caused to CCD optimum condition.
- انتشار مقاله: 24-03-1399
- نویسندگان: Rouhollah Hedayati,Morteza Hosseini,Ghasem Najafpour,Hosein Attar
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Pathology
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی: Solid pseudopapillary tumors of the pancreas (SPT) are rare tumors of the pancreas with low malignancy potential and a very good prognostic outcome after surgery. The outcome after radical resection is favourable. A case of solid-pseudopapillary tumor (SPT) of the pancreas in a 20-year-old woman is presented. The patient underwent resection of the mass in the pancreatic head and pancreaticoduodenectomy (Whipple procedure) with jejunostomy tube placement. We focus on the clinical features, imaging, and histopathological characteristics of solid-pseudopapillary tumors (SPT) of the pancreas.
- انتشار مقاله: 12-06-1390
- نویسندگان: Mohammad Reza Lashkarizadeh,Mehdi HayatbaKhsh,Hossein Nikpour,Moeenadin Savavi,Mahdiyeh Lashkarizadeh,Hosein Sattari
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Chemistry and Chemical Engineering
- نوع مقاله: Journal Article
- کلمات کلیدی: Viability,Prebiotic,Functional food,Probiotic,Simulated gastro-intestinal juices
- چکیده:
- چکیده انگلیسی: The aim of this work was to produce synbiotic apple juice and investigate the survival of Lactobacillus acidophilus and Lactobacillus plantarum in apple juice during the refrigerated storage (4 °C) for 42 days and then the ability of the mentioned probiotic bacteria in gastrointestinal tolerance under gastrointestinal tract conditions, with simulated gastric and bile juices. Eight-treatment combination Plackett-Burman design was used to evaluate the influence of seven variables such as probiotic strain, inoculum size, fructooligosaccharide content, inulin concentration, patulin content, ascorbic and citric acids concentration on the viability of mentioned probiotic strains. The results showed that the survivability of probiotics in apple juice depends significantly (P ≤ 0.05) on the inoculum size, inulin concentration, kind of probiotic strain, and ascorbic and citric acids’ concentration, respectively. The highest viability was achieved by inoculation of 108 CFU/mL of Lactobacillus acidophilus ATCC 4356 to the apple juice contaminated with 110 µg/L patulin content, containing 2.5% (w/v) inulin, 4 g/L citric acid, and 200 mg/L ascorbic acid. No significant difference was observed in the organoleptic properties of the synbiotic apple juice and the control sample. After sequential incubation in the simulated gastric (2 h) and intestinal juices (pH 7.4, 2 h), the highest number of surviving cells was around 3.5 log (CFU/mL).
- انتشار مقاله: 13-08-1396
- نویسندگان: Alaleh Zoghi,Kianoush Khosravi-Darani,Sara Sohrabvandi,Hosein Attar,Sayed Abolhasan Alavi
- مشاهده