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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Addiction and Health
- نوع مقاله: Journal Article
- کلمات کلیدی: Addiction,Detoxification,Buprenorphine,Buprenorphine/naloxone
- چکیده:
- چکیده انگلیسی: Background: Buprenorphine sublingual tablets are now available in Iran for opioid detoxification in clinics. Aim of the present study was to compare the efficiency of buprenorphine with buprenorphine/naloxone in short-term detoxification in a group of Iranian male opioid-dependent patients. Methods:A double-blind trial was carried out on a group of male opioid dependent patients in a psychiatric hospital in Kerman, Iran, during year 2017. A group of 100 men who met the diagnostic criteria for opiate dependence were included in the study from individuals who had referred for detoxification. They were allocated to the two groups receiving either buprenorphine (n = 51) or buprenorphine/naloxone (n = 49). Severity of withdrawal symptoms and signs were evaluated by Clinical Opiate Withdrawal Scale (COWS) and Adjective Rating Scale for Withdrawal (ARSW). Findings: The mean scores of COWS and ARSW in the two groups treated with buprenorphine and buprenorphine/naloxone significantly reduced from the first day to the fifth day of detoxification
(P < 0.050). Moreover, there was no significant difference between the two groups in terms of objective and subjective symptom reduction (P > 0.050). Conclusion: Buprenorphine/naloxone is as effective as buprenorphine in controlling opiate withdrawal symptoms.- انتشار مقاله: 23-02-1398
- نویسندگان: Hassan Ziaaddini,Shima Heshmati,Maryam Chegeni,Mahboobeh Mousavi-Ramezanzade,Shahrzad Mazhari
- مشاهده
- جایگاه : پژوهشی
- مجله: Addiction and Health
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی: Abstract Background: Considering the fear of drug addicts from hangover symptoms and the costs of withdrawal treatment and their importance in deciding to withdraw, it is helpful to identify various ways of withdrawal and their effects. This study investigated the withdrawal symptoms of two methods of detoxification with clonidine and rapid detoxification of clonidine with naltrexone. Methods: This was a clinical trial study. Patients referred to Shahid Beheshti hospital for narcotic addiction treatment were randomly divided into two groups. Group matching was done based on entry and excluding criteria. Data were collected using a demographic questionnaire including questions on the drug abuse and the consumption method, and a questionnaire on the symptoms of opioid withdrawal. Findings: Restlessness, vomiting, feeling sick and significant decrease of diastolic blood pressure was higher in rapid detoxification method group. However, considering background variables, Spearman correlation coefficient showed significant relationship just for lacrimation. Temptation for drug consumption was lower for heavy abusers in rapid detoxification method and in general, those who had higher amount of consumption and were treated by rapid detoxification, experienced less temptation for consumption. Conclusion: Rapid detoxification can be the first level treatment for heavy abusers, because it reduces the temptation for drug consumption and has shorter hospitalization and, as a result, has lower cost. Keyword: Drug abuse, Rapid detoxification, Clonidine detoxification, Withdrawal symptoms.
- انتشار مقاله: 17-08-1389
- نویسندگان: Hassan Ziaaddini,Abbas Qahestani,Maryam Moin Vaziri
- مشاهده
- جایگاه : پژوهشی
- مجله: Addiction and Health
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی: Abstract Background:Drug abuse is usually associated with behavioral disorders in children especially conduct disorder. This study investigated the behavioral disorders of children whose parents were opium or heroin dependent in compare with children whose parents were non-addicts to find the effects of drug abuse on offspring's behavior disorders by adjusting intervening factors. Methods: This case-control study, compared the behavioral disorders of 128 students (aged 8 to 14 years) in two groups of opium or heroin dependent parents and non–dependent parents (n = 64 in both groups) using Child Behavior Checklist (CBCL) questionnaire. Parents of both groups were checked not to have any significant psychiatric disorder (such as personality disorder or mood disorder), major health problem, and history of divorce. To compare percentages of the two groups, chi square and if required exact test were used. Findings:There was no statistically significant difference between the two groups in subscales of oppositional behavior problems and problems disorders. Conclusion: According to the results, in case there is no psychiatric co-morbidity associated with opium and heroin abuse, drug dependency does not seem to have any effect on disruptive bahavior disorder of children. Due to study limitations, the results cannot be generalized without conducting the study on a bigger population. Keywords: Disruptive behavior disorders, Opioid, Child behavior checklist (CBCL), Heroin, Opium.
- انتشار مقاله: 18-08-1389
- نویسندگان: Mahin Eslami Shahrbabaki,Hassan Ziaaddini,Hamdollah Saieedi,Nouzar Nakhaiee
- مشاهده
- جایگاه : پژوهشی
- مجله: Addiction and Health
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی: Abstract Background:Drug abuse is usually associated with behavioral disorders in children especially conduct disorder. This study investigated the behavioral disorders of children whose parents were opium or heroin dependent in compare with children whose parents were non-addicts to find the effects of drug abuse on offspring's behavior disorders by adjusting intervening factors. Methods: This case-control study, compared the behavioral disorders of 128 students (aged 8 to 14 years) in two groups of opium or heroin dependent parents and non–dependent parents (n = 64 in both groups) using Child Behavior Checklist (CBCL) questionnaire. Parents of both groups were checked not to have any significant psychiatric disorder (such as personality disorder or mood disorder), major health problem, and history of divorce. To compare percentages of the two groups, chi square and if required exact test were used. Findings:There was no statistically significant difference between the two groups in subscales of oppositional behavior problems and problems disorders. Conclusion: According to the results, in case there is no psychiatric co-morbidity associated with opium and heroin abuse, drug dependency does not seem to have any effect on disruptive bahavior disorder of children. Due to study limitations, the results cannot be generalized without conducting the study on a bigger population. Keywords: Disruptive behavior disorders, Opioid, Child behavior checklist (CBCL), Heroin, Opium.
- انتشار مقاله: 18-08-1389
- نویسندگان: Mahin Eslami Shahrbabaki,Hassan Ziaaddini,Hamdollah Saieedi,Nouzar Nakhaiee
- مشاهده
- جایگاه : پژوهشی
- مجله: Addiction and Health
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی: Abstract Background: Considering the fear of drug addicts from hangover symptoms and the costs of withdrawal treatment and their importance in deciding to withdraw, it is helpful to identify various ways of withdrawal and their effects. This study investigated the withdrawal symptoms of two methods of detoxification with clonidine and rapid detoxification of clonidine with naltrexone. Methods: This was a clinical trial study. Patients referred to Shahid Beheshti hospital for narcotic addiction treatment were randomly divided into two groups. Group matching was done based on entry and excluding criteria. Data were collected using a demographic questionnaire including questions on the drug abuse and the consumption method, and a questionnaire on the symptoms of opioid withdrawal. Findings: Restlessness, vomiting, feeling sick and significant decrease of diastolic blood pressure was higher in rapid detoxification method group. However, considering background variables, Spearman correlation coefficient showed significant relationship just for lacrimation. Temptation for drug consumption was lower for heavy abusers in rapid detoxification method and in general, those who had higher amount of consumption and were treated by rapid detoxification, experienced less temptation for consumption. Conclusion: Rapid detoxification can be the first level treatment for heavy abusers, because it reduces the temptation for drug consumption and has shorter hospitalization and, as a result, has lower cost. Keyword: Drug abuse, Rapid detoxification, Clonidine detoxification, Withdrawal symptoms.
- انتشار مقاله: 17-08-1389
- نویسندگان: Hassan Ziaaddini,Abbas Qahestani,Maryam Moin Vaziri
- مشاهده
- جایگاه : پژوهشی
- مجله: Addiction and Health
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی: Abstract Background: This study investigated the epidemiology of drug abuse among high school students in Kerman. Methods: This was a cross-sectional study on a randomly selected sample of 652 first and second grade high school students (256 boys, 396 girls) in Kerman. They were informed that their answers would be classified and nameless before they filled questionnaires. Schools and classes were selected using stratified sampling method. Findings: From total 652 students participated in this study, 39.2% (256) were boys and 60.7% (396) were girls. Most of the students had information about opium (70.7% of boys and 79.8% of girls), and then alcohol (55.9% of boys and 53.9% of girls). Most offered substance to the students was alcohol (25% in boys and 12.4% in girls). The most effective encouragement for using drugs was through their friends (39% in boys, 16.9% in girls). The most used drug was alcohol among boys (11.4%) and sedative tablets among girls (12.2%). Boys preferred to use drugs in wedding ceremonies (11.3%) but girls proffered their houses (4.8%). The first reason for using drugs was socializing with unsavory friends (29.4%) and the second one was domestic problems (21.4%). Conclusion: The results of this study indicated dangerously increase of drug abuse among teenagers, who are the future of the society. If these results could be generalized, authorities must think of serious solutions for this rising problem. Keywords: Substance abuse, Students, Narcotics
- انتشار مقاله: 17-08-1389
- نویسندگان: Nouzar Nakhaee,Hassan Ziaaddini,Ali Karimzadeh
- مشاهده
- جایگاه : پژوهشی
- مجله: Addiction and Health
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی: Abstract Background: This study aimed to estimate the prevalence of cigarette smoking and some of the related factors among schizophrenic and other hospitalized psychiatric patients. Methods: This was a cross-sectional study on 120 patients hospitalized in Shahid Beheshti hospital in Kerman in 2005. Patients were equally devided in two groups of schizophrenia and other psychiatric disorders. Sampling was based on statistical census and data were collected using a questionnaire including 27 questions on demographic data, psychiatric disorder, smoking cigarettes and other substances, and Fagerstrom test. Data were analyzed by Chi-square and ANOVA tests using SPSS software. Findings: Prevalence and severity of cigarette smoking was 71.6% and 6.47% among schizophrenic and 51.6% and 6.40% among other psychiatric patients, respectively and the difference was not significant. History of withdrawal was 25.6% and 58.1% in the schizophrenia and other disorders respectively and the difference was significant (P < 0.05). Addiction to other substances was 51.6% in schizophrenic and 45% in the other patients and the most prevalent substances in both groups were opium and alcohol. The severity of smoking cigarettes was 6.9 along with other drug abuses and 5.1 in cases with just smoking based on Fagerstrom test and the difference was significant (P < 0.05). Conclusion: The prevalence of cigarette smoking in both schizophrenia and other psychiatric patients is higher than normal population, but there is no significant difference between these two groups. Schizophrenic patients need persistent supportive and supervising programs for cigarette smoking abuse treatment because of their cognitive, motivate and social problems. Keywords: Cigarettes, Schizophrenia, Psychiatric disorders
- انتشار مقاله: 17-08-1389
- نویسندگان: Hassan Ziaaddini,Ali Kheradmand,Mostafa Vahabi
- مشاهده
- جایگاه : پژوهشی
- مجله: Addiction and Health
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی: Abstract Background: This study investigated the epidemiology of drug abuse among high school students in Kerman. Methods: This was a cross-sectional study on a randomly selected sample of 652 first and second grade high school students (256 boys, 396 girls) in Kerman. They were informed that their answers would be classified and nameless before they filled questionnaires. Schools and classes were selected using stratified sampling method. Findings: From total 652 students participated in this study, 39.2% (256) were boys and 60.7% (396) were girls. Most of the students had information about opium (70.7% of boys and 79.8% of girls), and then alcohol (55.9% of boys and 53.9% of girls). Most offered substance to the students was alcohol (25% in boys and 12.4% in girls). The most effective encouragement for using drugs was through their friends (39% in boys, 16.9% in girls). The most used drug was alcohol among boys (11.4%) and sedative tablets among girls (12.2%). Boys preferred to use drugs in wedding ceremonies (11.3%) but girls proffered their houses (4.8%). The first reason for using drugs was socializing with unsavory friends (29.4%) and the second one was domestic problems (21.4%). Conclusion: The results of this study indicated dangerously increase of drug abuse among teenagers, who are the future of the society. If these results could be generalized, authorities must think of serious solutions for this rising problem. Keywords: Substance abuse, Students, Narcotics
- انتشار مقاله: 17-08-1389
- نویسندگان: Nouzar Nakhaee,Hassan Ziaaddini,Ali Karimzadeh
- مشاهده
- جایگاه : پژوهشی
- مجله: Addiction and Health
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی: Abstract Background: This study aimed to estimate the prevalence of cigarette smoking and some of the related factors among schizophrenic and other hospitalized psychiatric patients. Methods: This was a cross-sectional study on 120 patients hospitalized in Shahid Beheshti hospital in Kerman in 2005. Patients were equally devided in two groups of schizophrenia and other psychiatric disorders. Sampling was based on statistical census and data were collected using a questionnaire including 27 questions on demographic data, psychiatric disorder, smoking cigarettes and other substances, and Fagerstrom test. Data were analyzed by Chi-square and ANOVA tests using SPSS software. Findings: Prevalence and severity of cigarette smoking was 71.6% and 6.47% among schizophrenic and 51.6% and 6.40% among other psychiatric patients, respectively and the difference was not significant. History of withdrawal was 25.6% and 58.1% in the schizophrenia and other disorders respectively and the difference was significant (P < 0.05). Addiction to other substances was 51.6% in schizophrenic and 45% in the other patients and the most prevalent substances in both groups were opium and alcohol. The severity of smoking cigarettes was 6.9 along with other drug abuses and 5.1 in cases with just smoking based on Fagerstrom test and the difference was significant (P < 0.05). Conclusion: The prevalence of cigarette smoking in both schizophrenia and other psychiatric patients is higher than normal population, but there is no significant difference between these two groups. Schizophrenic patients need persistent supportive and supervising programs for cigarette smoking abuse treatment because of their cognitive, motivate and social problems. Keywords: Cigarettes, Schizophrenia, Psychiatric disorders
- انتشار مقاله: 17-08-1389
- نویسندگان: Hassan Ziaaddini,Ali Kheradmand,Mostafa Vahabi
- مشاهده
- جایگاه : پژوهشی
- مجله: Addiction and Health
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی: Abstract Background: This study investigated the epidemiology of drug abuse among high school students in Kerman. Methods: This was a cross-sectional study on a randomly selected sample of 652 first and second grade high school students (256 boys, 396 girls) in Kerman. They were informed that their answers would be classified and nameless before they filled questionnaires. Schools and classes were selected using stratified sampling method. Findings: From total 652 students participated in this study, 39.2% (256) were boys and 60.7% (396) were girls. Most of the students had information about opium (70.7% of boys and 79.8% of girls), and then alcohol (55.9% of boys and 53.9% of girls). Most offered substance to the students was alcohol (25% in boys and 12.4% in girls). The most effective encouragement for using drugs was through their friends (39% in boys, 16.9% in girls). The most used drug was alcohol among boys (11.4%) and sedative tablets among girls (12.2%). Boys preferred to use drugs in wedding ceremonies (11.3%) but girls proffered their houses (4.8%). The first reason for using drugs was socializing with unsavory friends (29.4%) and the second one was domestic problems (21.4%). Conclusion: The results of this study indicated dangerously increase of drug abuse among teenagers, who are the future of the society. If these results could be generalized, authorities must think of serious solutions for this rising problem. Keywords: Substance abuse, Students, Narcotics
- انتشار مقاله: 17-08-1389
- نویسندگان: Nouzar Nakhaee,Hassan Ziaaddini,Ali Karimzadeh
- مشاهده