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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Iranian Journal of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی: Background: One of the most important post-operation problems encountered with Hepaticojejunostomy (Kasai operation) in patients with biliary atresia is cholangitis. The aim of this study was to evaluate the efficiency of anti-reflux valve in decreasing the incidence of cholangitis after hepaticojejunostomy. Methods: Ten dogs were randomly divided into two groups of equal size. In group A Roux-en-Y cholecystojejunostomy was performer and in group B antireflux valve was also added. Three months later, liver biopsy was taken to evaluate histopatholic changes. Results: The incidence of cholangitis was significantly reduced in dogs in which anti-reflux valve procedure was performed. Conclusions: Anti-reflux valve procedure effectively decreased post-Roux-en-Y cholecystojejunostomy cholangitis in dogs. Therefore it is plausible and might be beneficial for patients being treated for biliary atresia.Iran J Med Sci 2006; 31(2): 91-93. Keywords ● Cholangitis ● Kasai operation ● antireflux valve ● Roux-en-Y cholecystojejunostomy
- انتشار مقاله: 09-06-1394
- نویسندگان: H.R. Foroutan,U. Dasmeh,B. Geramizadeh,H.R. Kamalipour,N. Tanideh
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی: Chronic inflammatory demyelinating polyneuroradiculopathy (CIDP) is an immune mediated disorder characterized by progressive developing or relapsing symmetrical motor or sensory symptoms in more than one limb over a period of two months. Achalasia, as a primary esophageal motility disorder, is also characterized by increasing the tone of lower esophageal sphincter, absence or incomplete sphincter relaxation in response to swallowing, loss of esophageal peristalsis and rising intra-esophageal pressure. Herein, a case of CIDP, dysmotility-like symptoms, and achalasia is presented.
- انتشار مقاله: 25-06-1394
- نویسندگان: H.R. Foroutan,I. Vadiee,A. Nabavizadeh,M. Rafiee,M.H. Imanieh,A. Asadipouya,M. Pirastehfar
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی: Background: The bioavailability of metronidazole after oral ingestion, in ordinary conditions, is quite similar to intravenous administration of the drug. However, the degree of its absorption is not known in the early periods after laparotomy. Objective: To determine plasma levels of metronidazole in pediatric patients following elective abdominal surgery. Methods: The study group was comprised of 25 pediatric patients with mean age of 8.25 years. They took 10 mg/kg metronidazole (ingested or taken via nasogastric tube) a few hours after operation, followed by every eight hours for a total of three successive doses. We obtained blood samples 1-2 hours after each drug intake. Results: The mean±SD of plasma drug concentrations after the first, second and third doses were 1.43±0.81, 6.26±3.86 and 10.21±4.28 mg/ml, respectively, showing a significant rise after each dose (p<0.001). The majority of patients (84%) obtained a level equal to, or above the minimal bactericidal concentration (MBC) after the third dose. Ninety-two and 96% of patients achieved the plasma minimal inhibitory concentration or higher following the second and third doses, respectively, as compared to 4% after the first dose (p<0.00001). Conclusion: Absorption of oral metronidazole after elective laparotomy is disturbed only temporarily, as in the majority of patients the drug attains an acceptable level before the second post-operative day. Therefore, parenteral metronidazole therapy, if necessary, is recommended only during the first 24 hours, and it may be replaced by oral preparation afterward.
- انتشار مقاله: 09-09-1394
- نویسندگان: S.A. Banani,H.R. Foroutan,M.R. Panjehshahin
- مشاهده