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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Journal of Herbal Drugs
- نوع مقاله: Journal Article
- کلمات کلیدی: essential oil,Antimicrobial activity,Minimum inhibitory concentration,Zataria multiflora,Acinetobacter baumannii,Minimum bacterial concentration
- چکیده: مقدمه و هدف: هدف از این مطالعه بررسی فعالیت ضد میکروبی اسانس آویشن شیرازی بر روی اسینتو باکتر بومانی جدا شده از نمونه های بالینی است. روش تحقیق: دوازده سویه اسینتو باکتر بومانی از بیمارستان های شهرستان زابل جداسازی شد. اسانس آویشن شیرازی با استفاده از دستگاه کلونجر بدست آمد، در نهایت حداقل غلظت مهار کنندگی و حداقل غلظت کشندگی اسانس در برابر باکتریهای ذکرشده با روش میکرودایلوشن تعیین گردید. نتایج و بحث: نتایج حاصل از این مطالعه نشان داد که کمترین غلظت مهار کنندگی در برابر باکتری ها برابر با 31/0 میلی گرم بر میلی لیتر است و تنها یک سویه از باکتری در این غلظت مهار شده است. بیشترین غلظت مهار کننندگی برابر با 10 میلی گرم بر میلی لیتر بوده و یک سویه نیز در این غلظت مهار شده است. توصیه کاربردی و صنعتی: نتایج نشان داد که اسانس با افزایش غلظت اثرات ضد میکروبی آن افزایش پیدا می کند، اسانس آویشن فعالیت ضد میکروبی خوبی حتی در غلظت های پایین از خود نشان داد. با کاربرد اسانس آویشن شیرازی علیه باکتری های بیماریزا می توان به یک ماده ضد میکروبی خوب بدون اثر جانبی دست پیدا کرد.
- چکیده انگلیسی: Background & Aim: The aim of this study was to investigate the antimicrobial effects of Zataria multiflora against some Acinetobacter baumannii strains isolated from clinical samples. Experimental: Twelve strains of Acinetobacter baumannii were isolated from referred patients in Zabol hospital. Essential oil of Zataria multifloraspecies was extracted using Clevenger device. Minimum Inhibitory Concentration (MIC) and Minimum Bacterial Concentration (MBC) of essential oil on mentioned bacteria were determined using micro dilution broth method at six different concentrations. Results: The results of this study showed that the lowest inhibitory concentration of essential oil against bacteria was 0.31 mg/ml, and only one strain of bacteria was inhibited. However, the highest inhibitory concentration was estimated 10 mg/ml. Recommended applications/industries: The results showed that the antimicrobial effects increased with increasing in essential oil concentration and the essence showed good antimicrobial activity even at low concentrations. With the use of essential oil of Zataria multiflora against bacterial pathogens, a good antimicrobial agent can be obtained without any side effects.
- انتشار مقاله: 18-07-1396
- نویسندگان: Khadije Rezaie Keikhaie,Gholamreza Bagheri,Mehdi Hassanshahian,Saeide Saeidi
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Neonatology
- نوع مقاله: Journal Article
- کلمات کلیدی: Screening,Glucometer,Neonatal hypoglycemia
- چکیده:
- چکیده انگلیسی: Background: Hypoglycemia is one of the most common neonatal disorders, associated with severe complications. There has been a great deal of controversy regarding the definition and screening of hypoglycemia. Therefore, in this study, we aimed to determine a cut-off value for blood glucose level in glucometer readings.
Methods: This cross-sectional study was conducted on 238 newborns at risk of hypoglycemia, admitted to Baqiyatallah Hospital of Tehran, Iran in 2012; the subjects were selected via simple sampling. After obtaining informed consents from the newborns’ parents, 1 cc blood samples were sent to the laboratory for measuring the blood glucose level. Moreover, venous blood samples, as well as heel-stick blood samples, were obtained for glucometer measurements. Blood glucose measurements were used to determine the cut-off value by the receiver operating characteristic (ROC) curve and make comparisons with the diagnostic criteria for hypoglycemia in the literature.
Results: A total of 238 infants with the mean weight of 2869±821.9 g were enrolled in this study. The mean (±SD) blood glucose levels were 65.1±22.9, 82.9±24.7, and 84.4±24.8 mg/dl, based on the standard laboratory method, glucometer reading of venous blood samples, and glucometer reading of heel-stick capillary blood samples, respectively. The optimal cut-off point for hypoglycemia was determined as 65 mg/dl, using glucometer-based assessment of heel-stick blood samples.
Conclusion: The significant difference in blood glucose levels measured by the laboratory method and outpatient glucometer readings highlights the importance of a cut-off value for rapid assessment and control of blood glucose and timely detection of hypoglycemia. In fact, the cut-off value introduced in the present study could facilitate such measurements.- انتشار مقاله: 01-01-1395
- نویسندگان: Mohammad Torkaman,Gholamreza Bagheri,Ahmad Ahmadi,Amin Saburi
- مشاهده
- جایگاه : پژوهشی
- مجله: Advanced Herbal Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Antimicrobial activity,Pseudomonas aeruginosa,Zinc oxide nanoparticles,Solanum nigrum
- چکیده:
- چکیده انگلیسی: Background and aims: The purpose of this study was to evaluate the antimicrobial effects of zinc oxide nanoparticale and extract of Solanum nigrum on Pseudomonas aeruginosa bacteria isolated from clinical specimens.
Methods: Zinc oxide was purchased from the market. 20g of the dried and pounded leaves of S. nigrum was used and its extract was prepared in rotary device. 12 isolates of P. aeruginosa were isolated from referred patients to hospital Zabol. Finally, 12 isolates were used to growth inhibitory activity assay. Minimum bactericidal concentration (MBC) and minimum inhibitory concentration (MIC) of Zinc oxide and extract plant against P.aeruginosa were evaluated using micro broth dilution method.
Results:The highest inhibitory concentration for P. aeruginosa is 1500 μg/ml, with four bacterial strains being inoculated. Also, the results showed that the highest drainage concentration was 3000 μg/ml, which two strains were inhibited in this concentration and the lowest trap concentration was 93 μg/ml. The lowest inhibitory concentration of extract plant was 0.62 mg / ml, with only one strain being inhibited in this concentration. The highest inhibitory concentration for P. aeruginosa is 40 mg / ml, with four bacterial strains being inoculated.
Conclusion:The results showed that zinc oxide and extract of Solanum nigrum have a good antimicrobial activity on the bacterium and increases the concentration of antimicrobial activity.- انتشار مقاله: 18-07-1396
- نویسندگان: Khadijeh Rezaie.Keikhaie,Gholamreza Bagheri,Saeide Saeidi,Mehdi Hassanshahian
- مشاهده