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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: International Journal of Travel Medicine and Global Health
- نوع مقاله: Journal Article
- کلمات کلیدی: Survey,Egypt,Malaria,Travel Health,Vaccine-Preventable Diseases
- چکیده:
- چکیده انگلیسی: Introduction: More than one third of travelers to developing countries report health problems when traveling. The Egyptian Ministry of Health reports the occurrence of 400 cases of malarial infection yearly among Egyptian travelers. This article aimed to assess the knowledge, attitude, and practice (KAP) of Egyptian travelers towards infectious diseases, vaccination, and malaria chemoprophylaxis.
Methods: A survey was conducted at Cairo International Airport and included 1500 travelers. The questionnaire inquired about the travelers’ knowledge about infectious diseases at their destinations and their KAP regarding vaccination, malaria, and its prophylaxis.
Results: Most travelers (68%) had poor knowledge, specifically; 90.2%, 85.6%, 88.5% did not know the endemic diseases at their destinations, the modes of disease transmission, or the protective measures against disease, respectively. Knowledge about malaria prevalence, symptoms, modes of transmission, and prevention was good in only 18%, 29.8%, 6.7%, and 21.4% of travelers, respectively. Poor practice of malaria prophylactic measures was found in 66.3% of travelers. Although 91.3% did not receive any vaccination, the general attitude towards vaccination was good. The total travel health knowledge, practice, general attitude toward vaccination, and the perceived benefits of malarial prophylaxis scores were significantly correlated with older age and high socioeconomic level. Most of the studied travelers (90.4%) did not carry or use malaria chemoprophylaxis. Ignorance was the main barrier to receiving vaccines (65.3%) and to adherence to malaria chemoprophylaxis (88.3%).
Conclusion: Egyptian travelers have poor travel health knowledge and practices. Their knowledge and practice scores improve with older age, urban residence, and higher educational levels. They have a good attitude towards vaccination, and ignorance was the main barrier to sound practices.- انتشار مقاله: 06-05-1397
- نویسندگان: Engy Mohamed El-Ghitany,Mohamed Abdelmohsen,Azza Galal Farghaly,Ensaf Saied Abd El-Gawwad,Ekram Wassim Abd El-Wahab
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Performance,response,MPM,perdictors
- چکیده:
- چکیده انگلیسی:
Purpose: Malignant pleural mesothelioma (MPM) has a poor prognosis in general. Here we sought to evaluate prognostic factors and predictors of response to chemotherapy in good performance (PS=0-I) patients. Methods: We retrospectively reviewed our database and enrolled patients with MPM who received platinum containing chemotherapy (2012-2014). Clinico-pathological and laboratory data were retrieved and Cox and logistic regression multivariate analyses (MVA) were respectively used to identify predictors of survival and response to chemotherapy. Comparison of good vs poor performance status (PS≥II) was accomplished using the Chi (X2) test. Kaplan–Meier survival curves were also obtained and propensity-score matching was performed for survival comparison. Results: Among 114 patients listed during the study period, 82 had good PS=0-I (median age 45years, 43 men, 30 smokers, median weight=77Kg, pretreatment haemoglobin (Hb) level=12g/dL, platelet count=372,000/μL, leukocytes=9,700/μL, neutrophils=6,100/μL, lymphocytes=1,890/μL and neutrophil/lymphocyte ratio (NLR)=3.60 ). Some 65 had asbestosis, 23 had chronic disease, 55 (67.1%) were responders to platinum containing first line chemotherapy. A total of 49 (59.8%) had epithelial MPM. Median-OS and PFS in good PS cases were 17 and 9 months, respectively, as compared to 16 and 8 months for the poor PS group. After matching, better OS was observed among good PS vs poor PS patients (p=0.024) but there was no PFS difference (p=0.176). Significant decrease in PFS was observed among those with advanced nodal N disease (median PFS in N0 and N+ was 10 and 5 months, respectively), non-responders (p=0.012), NLR (p=0.026) and those with an epithelial pathology (p=0.062). MVA demonstrated that advanced (N) status (p=0.015), being a non-responder (p<0.001), NLR (p=0.015) and smoking (p=0.07) adversely affected the prognosis. The only predictor of response was absence of metastasis (M0; p=0.04). Conclusions: In addition to previously recognized factors, like nodal status, response, smoking and NLR, better median survival was evident in our patients with a good PS. Early detection before development of metastasis warrants greater focus to allow better responses to be obtained.- انتشار مقاله: 27-10-1395
- نویسندگان: Mohamed Rahouma,Hala Aziz,Galal Ghaly,Mohamed Kamel,Iman Loai,Abdelrahman Mohamed
- مشاهده