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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Journal of Herbal Drugs
- نوع مقاله: Journal Article
- کلمات کلیدی: Staphylococcus aureus,Plant extract,Datura Stramonium,Prosopis Farcta
- چکیده: مقدمه و هدف: هدف از این مطالعه بررسی فعالیت ضد میکروبی عصاره دو گیاه دارویی جغجغه و تاتوره بر روی استافیلوکوکوس اورئوس جدا شده از بینی گوسفندان در شهرستان زابل است.
روش تحقیق: گیاه تاتوره و جغجغه از مناطق شهر زابل جمع آوری شد. سویه های استافیلوکوکوس اورئوس از بینی گوسفندان شهرستان زابل جمع آوری شد. الگوی مقاومت آنتی بیوتیکی با روش کربی بائر تعیین شد. حداقل غلظت مهار کنندگی و حداقل غلظت کشندگی با روش میکرودایلوشن تعیین شد.
نتایج: نتایج مطالعه حاضر نشان داد که حداقل غلظت مهار کنندگی عصاره جغجغه برابر با ppm25 بوده است و 10 سویه در این غلظت مهار شده اند. کمترین غلظت مهار کنندگی عصاره تاتوره ppm 6.25 بوده و یک سویه در این غلظت مهار شد. بیشترین غلظت مهار کنندگی برابر با ppm 50 و بیشترین غلظت کشندگی ppm 100 مشاهده شد.
توصیه های کاربردی/ صنعتی: نتایج این مطالعه مبنی بر اثر ضد میکروبی خوب عصاره گیاه تاتوره و جغجغه نشان داد که میتواند برای درمان عفونت های استافیلوکوکی استفاده شود.- چکیده انگلیسی: Background & Aim: The aim of this study was to investigate the antimicrobial activity of two rangeland-medical plants extracts, Prosopis farcta L. and Datura stramonium L., against Staphylococcus aureus isolated from sheep in Zabol city.
Experimental: The P. farcta and D. stramonium were collected from the rangelands of Zabol city. Staphylococcus aureus strains were isolated from the nose of sheep in Zabol city. Antibiotic resistance pattern was determined by Kirby Bauer method. Finally, the minimum inhibitory concentration (MIC) and minimum bactericide concentration (MBC) were determined by microdilution method.
Results: The results of this study showed that the P.farcta extract had a MIC of 25 ppm, and 10 strains of the bacterium were inhibited in this concentration. The lowest inhibitory concentration of D.stramonium extract was 6.25 ppm, and one strain was inhibited in this concentration. On the other hand, the highest inhibitory concentration was 50 ppm and the highest bactericide concentration was 100 ppm.
Recommended applications/ industries: The results of this study showed good antimicrobial effects of D. stramonium and P. farcta extracts that can be used to treat Staphylococcus aureus infections.- انتشار مقاله: 17-02-1397
- نویسندگان: Saeide Saeidi,Nafiseh Mahdi Nezhad,Majid Sharifi-Rad,Fereshteh Javadian,Elham Javadian
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Advanced Biological and Biomedical Research
- نوع مقاله: Journal Article
- کلمات کلیدی: Human pathogens,silver nanoparticles,Rosmarinus officinalis
- چکیده:
- چکیده انگلیسی: The synthesis of nanoparticles from biological processes is evolving a new era of research interests in nanotechnology. The aim of this study was to determined antibacterial activity of silver nanoparticles produced by Rosmarinus officinalis L leaf extract against some human pathogenic bacteria. The formation and characterisation of AgNPs were confirmed by UV-Vis spectroscopy, energy-dispersive spectroscopy (EDX), X-ray diraction (XRD) and transmission electron microscope (TEM). All strains were obtained from standard laboratory and the minimum inhibitory concentrations were investigated by microdulition method.The result show that, the levels of MIC was observed ranges from 1.25 to 2.5 mg/ml. The highest MIC value was observed against S.pneumoniae, Hafnia alvei, S. saprophyticus.
- انتشار مقاله: 28-12-1394
- نویسندگان: Saeide Saeidi,Fereshteh Javadian,Zahra Sepehri,Zahra Shahi,Razieh Farazmand,Mahmood Anbari
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Advanced Biological and Biomedical Research
- نوع مقاله: Journal Article
- کلمات کلیدی: Antibacterial activity,E. coli,Nano silver
- چکیده:
- چکیده انگلیسی: The aim study antibacterial effects of silver nanoparticles against resistant strains of E.coli bacteria.12 strains of E. coli strains arising urinary infection were isolated from hospitalized patient in zabolhospitals. Minimum inhibitory concentration of winter cherry were determined by dilution method in various concentration on bacteria. The highest MIC values was found to be 100ppm against one E.coli and the least MIC values was observed in 12.5 ppm. This work, integrates nanotechnology and bacteriology, leading to possible advances in the formulation of new types of bactericides.
- انتشار مقاله: 28-12-1394
- نویسندگان: Saeide Saeidi,Fereshteh Javadian,Zahra Sepehri,Zahra Shahi,Fahime Mousavi,Mahmood Anbari
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Advanced Biological and Biomedical Research
- نوع مقاله: Journal Article
- کلمات کلیدی: Escherichia coli,Extract,Calotropis procera,Antibiot resistant
- چکیده:
- چکیده انگلیسی: Infectious diseases are responsible for thousands of worldwide early death .Many commercial antibiotics have been used to control human's infectious diseases all over the world. Calotropis procera Linn a wild growing plant of Asclepiadaecae family is known to possess multifarious medicinal properties. Total 80 non repetitive clinical E. coli strains recovered during 7 month, and were screened for ESBL production by disc diffusion test, and the MIC and MBC of Calotropis procera chlorophyll extract against ESBL positive E. coli isolates were determined. The results showed a total of 30 of 80 (37.5%) isolates harboured ESBL enzymes. Calotropis procera Calotropis procera extract were effective against ESBL producing E. coli isolates. There is need for a correct and reliable phenotypic test to identify ESBL beta lactamases and also these bioactive plants may help alleviate the problem of drug resistance. The presence of these chemical constituents in this plant is an indication that the plant, if properly screened using additional solvents, could yield drugs with pharmaceutical significance
- انتشار مقاله: 06-05-1393
- نویسندگان: Fereshteh Javadian,Shahla Sahraei,Arezoo Azizi
- مشاهده
- جایگاه : پژوهشی
- مجله: Current Medical Mycology
- نوع مقاله: Journal Article
- کلمات کلیدی: Iran,Extract,antimicrobial effect,Echinophora platyloba,Rosmarinus officinalis
- چکیده:
- چکیده انگلیسی: Abstract
Background and Purpose: In traditional medicine, herbal products still remain the principal source of pharmaceutical
agents. The present study aimed to investigate the antifungal effects of Echinophora platyloba and Rosmarinus officinalis
extracts on C. albicans species.
Materials and Methods: The aqueous and ethanolic leaf extracts of E. platyloba and R. officinalis, collected from the
mountainous regions of Iran, were screened in terms of antimicrobial activity against C. albicans strains, using the agar
well diffusion method. The minimum inhibitory concentration was determined by the microtitration technique.
Results: Overall, the results showed that the leaf extracts of E. platyloba and R. officinalis had strong antimicrobial
activities. Also, based on the findings, R. officinalis leaf extracts exhibited higher antimicrobial activity. The ethanolic
leaf extracts of E. platyloba and R. officinalis showed good antimicrobial activity against C. albicans strains. However,
the aqueous extracts did not show any major activities against the tested C. albicans strains. On the other hand, the
ethanolic extracts exhibited major antimicrobial properties against C. albicans strains. The highest minimum inhibitory
concentration was reported in E. platyloba leaf extracts.
Conclusion: The present results indicated some advantages of E. platyloba and R. officinalis leaf extracts, which could be
applied for the treatment of microbial infections- انتشار مقاله: 18-04-1398
- نویسندگان: Zahra Sepehri,Fereshteh Javadian,Davoud Khammari,Mehdi Hassanshahian
- مشاهده
- جایگاه : پژوهشی
- مجله: Advanced Herbal Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Candida albicans,Extract plant,Withania somnifera,Antifungal effects
- چکیده:
- چکیده انگلیسی: Background and aims: Withania somnifera (W. somnifera), commonly known as Ashwagandha, is an important medicinal plant that has been used in Ayurvedic and indigenous medicine for over 3,000 years. Candidiasis is one of the most common opportunistic fungal diseases in humans. In fact, the most important fungal disease in women is vaginal candidiasis. This study aimed to investigate the antifungal effects of the extracts of the W. somnifera on Candida albicans (C. albicans).
Methods: In this experimental research, 9 vaginal samples were collected using the sterile swap and Falcon tube by the gynecological specialists. The extracts of the shallot and artichoke were prepared using a rotary device. The inhibitory concentration against C. albicans was determined using incubation in media.
Results: The results of this study suggested that the minimum inhibitory concentration (MIC) against C. albicans, which is equivalent 50 ppm to 250 ppm has the highest concentration of inhibitor.
Conclusion: The results of this study showed that the antifungal activity of wind cheese against C. albicans is good, so it can be used as a drug to treat infections caused by C. albicans.- انتشار مقاله: 09-12-1394
- نویسندگان: Fereshteh Javadian,Zahra Sepehri,Saeideh Saeidi,Mehdi Hassanshahian
- مشاهده