در هنگام جستجو کلمه در قسمت عنوان میتوانید کلمات مورد جستجو را با کاراکتر (-) جدا کنید.
کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Journal of Dental Materials and Techniques
- نوع مقاله: Journal Article
- کلمات کلیدی: Quality of Life,OIDP,oral impacts,adult patients
- چکیده:
- چکیده انگلیسی: Introduction: Quality of life is defined as the sense of well-being and satisfaction with daily performances influenced by dental and oral conditions. Oral diseases are very common and have impacts on different aspects of individual's life and can change their performances. In other word, they can change the quality of life. The real impact of health and disease on daily performances is considered as Health-Related Quality of Life. The aim of this study was to evaluate the impacts of oral diseases on quality of life in patients referred to Mashhad Faculty of Dentistry and Jahad Dental Clinic. Methods: This cross-sectional study was performed using non randomized sampling method. For this study, 500 patients referred to Mashhad Faculty of Dentistry and Jahad Dental Clinic with age >15 years were recruited. An educated interviewer asked the questions of the Persian version of OIDP questionnaire, which was valid and reliable for Iranian population. In this index the frequency and severity of each impact were recorded. Finally, each was attributed to specific oral conditions, as indicated by the respondents. The OIDP score is expressed as the sum of the different performance scores divided by the maximum possible score. Results: According to the results of this study, 84% of patients had negative impacts on their quality of life. Gender and job had significant associations with OIDP score. There was not any significant association between OIDP score and general health. The most and the least commonly affected daily performances were eating and going out, respectively. Conclusion: The most and the least effective oral diseases were toothache and tooth size and shape, respectively so the most treatment need is root canal therapy and tooth repair and to relieve pain.
- انتشار مقاله: 09-07-1392
- نویسندگان: Amir Moeintaghavi,Hamidreza Arab,Naser Sargolzaei,Mojtaba Dorri,Fatemeh Darvishzadeh,Mahyareh Alizadeh
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Dental Materials and Techniques
- نوع مقاله: Journal Article
- کلمات کلیدی: Quality of Life,OIDP,oral impacts,adult patients
- چکیده:
- چکیده انگلیسی: Introduction: Quality of life is defined as the sense of well-being and satisfaction with daily performances influenced by dental and oral conditions. Oral diseases are very common and have impacts on different aspects of individual's life and can change their performances. In other word, they can change the quality of life. The real impact of health and disease on daily performances is considered as Health-Related Quality of Life. The aim of this study was to evaluate the impacts of oral diseases on quality of life in patients referred to Mashhad Faculty of Dentistry and Jahad Dental Clinic. Methods: This cross-sectional study was performed using non randomized sampling method. For this study, 500 patients referred to Mashhad Faculty of Dentistry and Jahad Dental Clinic with age >15 years were recruited. An educated interviewer asked the questions of the Persian version of OIDP questionnaire, which was valid and reliable for Iranian population. In this index the frequency and severity of each impact were recorded. Finally, each was attributed to specific oral conditions, as indicated by the respondents. The OIDP score is expressed as the sum of the different performance scores divided by the maximum possible score. Results: According to the results of this study, 84% of patients had negative impacts on their quality of life. Gender and job had significant associations with OIDP score. There was not any significant association between OIDP score and general health. The most and the least commonly affected daily performances were eating and going out, respectively. Conclusion: The most and the least effective oral diseases were toothache and tooth size and shape, respectively so the most treatment need is root canal therapy and tooth repair and to relieve pain.
- انتشار مقاله: 09-07-1392
- نویسندگان: Amir Moeintaghavi,Hamidreza Arab,Naser Sargolzaei,Mojtaba Dorri,Fatemeh Darvishzadeh,Mahyareh Alizadeh
- مشاهده
- جایگاه : پژوهشی
- مجله: Addiction and Health
- نوع مقاله: Journal Article
- کلمات کلیدی: Morphine,Rats,ginger,p38 Mitogen-Activated Protein Kinases,Glial fibrillary acidic protein,Nucleus Accumbens
- چکیده:
- چکیده انگلیسی: Background: Chronic usage of morphine elicits the production of inflammatory factors by glial cells and
induces neuroinflammation. Ginger (Zingiber Officinale Roscoe) is a medicinal herb that has antiinflammatory properties. It has been reported that ginger shows anti-addictive effects against chronic usage
of morphine; however, its influence on morphine-induced neuroinflammation has not yet been clarified.
Methods: Morphine (12 mg/kg) was administrated intraperitoneally for 6 consecutive days. To evaluate the
effect of ginger on morphine-induced neuroinflammation, ginger extract (100 mg/kg) was given orally 30
minutes before morphine. Glial fibrillary acidic protein (GFAP) and P38 mitogen-activated protein kinase
(p38 MAPK) levels were assayed by immunoblotting in the rat nucleus accumbens (NAcc).
Findings: The injection of chronic morphine increased the levels of proteins involved in neuroinflammation
(p38 MAPK and GFAP) in NAcc. Furthermore, the levels of p38 MAPK and GFAP significantly returned to
the control levels by ginger extract.
Conclusion: The results suggest that the ginger extract can reduce morphine-induced neuroinflammation in NAcc.
- انتشار مقاله: 13-04-1398
- نویسندگان: Shima Torkzadeh-Mahani,Saeed Esmaeili-Mahani,Sima Nasri,Fatemeh Darvishzadeh,Reyhaneh Naderi
- مشاهده