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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: specificity,Recall rates,Sensitivity,reader’s performance,screening mammography
- چکیده:
- چکیده انگلیسی: Rationale and objectives: Target recall rates are often used as a performance indicator in mammography screening
programs with the intention of reducing false positive decisions, over diagnosis and anxiety for participants. However,
the relationship between target recall rates and cancer detection is unclear, especially when readers are directed to
adhere to a predetermined rate. The purpose of this study was to explore the effect of setting different recall rates on
radiologist’s performance. Materials and Methods: Institutional ethics approval was granted and informed consent
was obtained from each participating radiologist. Five experienced breast imaging radiologists read a single test set
of 200 mammographic cases (20 abnormal and 180 normal). The radiologists were asked to identify each case that
they required to be recalled in three different recall conditions; free recall, 15% and 10% and mark the location of any
suspicious lesions. Results: Wide variability in recall rates was observed when reading at free recall, ranging from
18.5% to 34.0%. Readers demonstrated significantly reduced performance when reading at prescribed recall rates,
with lower sensitivity (H=12.891, P=0.002), case location sensitivity (H=12.512, P=0.002) and ROC AUC (H=11.601,
P=0.003) albeit with an increased specificity (H=12.704, P=0.002). However, no significant changes were evident in
lesion location sensitivity (H=1.982, P=0.371) and JAFROC FOM (H=1.820, P=0.403). Conclusion: In this laboratory
study, reducing the number of recalled cases to 10% significantly reduced radiologists’ performance with lower detection
sensitivity, although a significant improvement in specificity was observed.- انتشار مقاله: 19-04-1397
- نویسندگان: Norhashimah Mohd Norsuddin,Claudia Mello-Thoms,Warren Reed,Sarah Lewis
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Breast cancer,Mammographic density,Mongolia
- چکیده:
- چکیده انگلیسی:
Objective: Mammographic density (MD) is a significant risk factor for breast cancer and an important determinant for establishing efficiency of any screening program. Currently, the distribution and influential factors of MD is unknown among Mongolian women. This work aims to characterize MD of Mongolian women. Methods: The ethical approval was obtained from Research Ethics Board of the University of Sydney (2014/973) and National Ethic Committee from Ministry of Mongolia (2015/04). We recruited 1985 women aged 16-83 from the National Cancer Center in Mongolia for whom MD and age of each woman was known. From this total group, 983 women also had additional available details on height, weight, body mass index (BMI) and area of residency. We investigated the association of each of these variables with breast density, which was assessed by using the Breast Imaging Reporting and Data System (BIRADS) lexicon. Univariate and multivariate regression analyses were conducted to explore the importance of these variables as predictors of MD. Results: Category B (33%) was the most common type of MD, whereas 25%, 18% and 24% of women belonged to the category A, C and D respectively. The univariate analysis demonstrated that, younger women had more dens breasts than their older counterparts (OR=6.8). Also, increased MD was significantly (p<0.05) associated with decreased weight (OR=4.5), increased height (OR=0.4) and lower BMI (OR=13.2). Urban women had significantly higher MD compared with rural counterparts (OR=2.2). In the multivariate analysis, 75% of variation in MD was explained by age (OR=4.5) and BMI (OR=7.3). Conclusion: A high proportion of Mongolian women have very high density breasts and age and body size are key factors determining MD among these women.- انتشار مقاله: 22-01-1396
- نویسندگان: Delgermaa Demchig,Claudia Mello-Thoms,Khulan Khurelsukh,Asai Ramish,Patrick C Brennan
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Breast cancer,Mammographic density,Mongolia
- چکیده:
- چکیده انگلیسی:
Objective: Mammographic density (MD) is a significant risk factor for breast cancer and an important determinant for establishing efficiency of any screening program. Currently, the distribution and influential factors of MD is unknown among Mongolian women. This work aims to characterize MD of Mongolian women. Methods: The ethical approval was obtained from Research Ethics Board of the University of Sydney (2014/973) and National Ethic Committee from Ministry of Mongolia (2015/04). We recruited 1985 women aged 16-83 from the National Cancer Center in Mongolia for whom MD and age of each woman was known. From this total group, 983 women also had additional available details on height, weight, body mass index (BMI) and area of residency. We investigated the association of each of these variables with breast density, which was assessed by using the Breast Imaging Reporting and Data System (BIRADS) lexicon. Univariate and multivariate regression analyses were conducted to explore the importance of these variables as predictors of MD. Results: Category B (33%) was the most common type of MD, whereas 25%, 18% and 24% of women belonged to the category A, C and D respectively. The univariate analysis demonstrated that, younger women had more dens breasts than their older counterparts (OR=6.8). Also, increased MD was significantly (p<0.05) associated with decreased weight (OR=4.5), increased height (OR=0.4) and lower BMI (OR=13.2). Urban women had significantly higher MD compared with rural counterparts (OR=2.2). In the multivariate analysis, 75% of variation in MD was explained by age (OR=4.5) and BMI (OR=7.3). Conclusion: A high proportion of Mongolian women have very high density breasts and age and body size are key factors determining MD among these women.- انتشار مقاله: 22-01-1396
- نویسندگان: Delgermaa Demchig,Claudia Mello-Thoms,Khulan Khurelsukh,Asai Ramish,Patrick C Brennan
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Breast cancer,Mammographic density,Mongolia
- چکیده:
- چکیده انگلیسی:
Objective: Mammographic density (MD) is a significant risk factor for breast cancer and an important determinant for establishing efficiency of any screening program. Currently, the distribution and influential factors of MD is unknown among Mongolian women. This work aims to characterize MD of Mongolian women. Methods: The ethical approval was obtained from Research Ethics Board of the University of Sydney (2014/973) and National Ethic Committee from Ministry of Mongolia (2015/04). We recruited 1985 women aged 16-83 from the National Cancer Center in Mongolia for whom MD and age of each woman was known. From this total group, 983 women also had additional available details on height, weight, body mass index (BMI) and area of residency. We investigated the association of each of these variables with breast density, which was assessed by using the Breast Imaging Reporting and Data System (BIRADS) lexicon. Univariate and multivariate regression analyses were conducted to explore the importance of these variables as predictors of MD. Results: Category B (33%) was the most common type of MD, whereas 25%, 18% and 24% of women belonged to the category A, C and D respectively. The univariate analysis demonstrated that, younger women had more dens breasts than their older counterparts (OR=6.8). Also, increased MD was significantly (p<0.05) associated with decreased weight (OR=4.5), increased height (OR=0.4) and lower BMI (OR=13.2). Urban women had significantly higher MD compared with rural counterparts (OR=2.2). In the multivariate analysis, 75% of variation in MD was explained by age (OR=4.5) and BMI (OR=7.3). Conclusion: A high proportion of Mongolian women have very high density breasts and age and body size are key factors determining MD among these women.- انتشار مقاله: 22-01-1396
- نویسندگان: Delgermaa Demchig,Claudia Mello-Thoms,Khulan Khurelsukh,Asai Ramish,Patrick C Brennan
- مشاهده