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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Women’s Health Bulletin
- نوع مقاله: Journal Article
- کلمات کلیدی: experience,Stigmatization,Infertile Females,Psychosocial Problem
- چکیده:
- چکیده انگلیسی: Background: Infertility is a complex phenomenon, which threatens everyone and every family. Females are threatened more due to various social differences. Objectives: The goal of this study was to explore the experiences of infertile females, who had referred to a public center of infertility in Shiraz, Iran. Methods: This was a qualitative study based on four focus groups and four in-depth interviews with 25 infertile females. Transcribed data were analyzed using conventional content analysis. Results: Four themes were extracted from the data, which were life without excitement, social pressures, low self-esteem and treatment problems. Although it seems that these themes are variable, they present a total reality, which leads to a bitter life. Conclusions: Infertile females are under multidimensional pressures involving psychological, social and economic aspects of their life and interpersonal relationships. This condition leads to a bitter situation for these people.
- انتشار مقاله: 11-10-1348
- نویسندگان: Ahmad Kalateh Sadati,Farnaz Rahnavard,Bahia Namavar Jahromi
- مشاهده
- جایگاه : پژوهشی
- مجله: Women’s Health Bulletin
- نوع مقاله: Journal Article
- کلمات کلیدی: Gestational diabetes,Energy Expenditure,Exercise Characteristics
- چکیده:
- چکیده انگلیسی: Background: Although exercise is recommended for preventing gestational diabetes mellitus (GDM), the situation has remained unclear regarding the characteristics and timing of the proper exercise. Objectives: The aim of the present study was to compare exercise characteristics including volume, frequency, intensity and energy expenditure before and during pregnancy in diabetic and non-diabetic pregnant women. Patients and Methods: Participants of the study included 137 pregnant women (80 diabetics and 57 non-diabetics) who were selected based on the inclusion criteria. Exercise activities of the participants were evaluated by interviews. Statistical tests of Mann-Whitney and Chi-square were used for data analysis. Results: Participating in regular exercise activities was significantly higher in the non-diabetics compared to the diabetics during all stages including 8 and 1 years before pregnancy and during the 1st and 2nd trimesters of pregnancy (P < 0.05). However among the diabetics and non-diabetics who regularly exercised, there was no significant difference in terms of exercise characteristics (frequency, intensity, duration and energy cost). Conclusions: Regular participation in exercise activities before and during pregnancy especially during the second trimester is important for preventing GDM. However, in few cases, similar exercise characteristics were found among diabetics and non-diabetics.
- انتشار مقاله: 11-10-1348
- نویسندگان: Sayyede Esmat Moosavi,Maryam Koushkie Jahromi,Bahia Namavar Jahromi
- مشاهده
- جایگاه : پژوهشی
- مجله: Women’s Health Bulletin
- نوع مقاله: Journal Article
- کلمات کلیدی: Periodontitis,Periodontal Diseases,Preeclampsia,Low birth weight,Gingivitis
- چکیده:
- چکیده انگلیسی: Background: Preeclampsia is a unique idiopathic syndrome in human pregnancy that can involve almost all organ systems. Objectives: The aim of the present study was to compare the periodontal diseases between the preeclamptic and normal pregnant women in order to find a possible risk factor relationship. Materials and Methods: This case-control study was performed on 200 pregnant women, with maternal age ≤ 35 years and gestational age ˃ 20 weeks with singleton pregnancies. Of these, 100 women were preeclamptic with proteinuria and blood pressure ≥ 140/90 and 100 women with normal blood pressure in the control group. Oral examination was performed on all women by a dentist for detection of periodontal diseases. Gingivitis and periodontitis were diagnosed based on the American Academy of Periodontology (AAP)/American Dental Association (ADA) classification, using the measurement method of Ramfjord. The preeclamptic women were then sub-classified into mild and moderate and comparisons were made between all groups. Results: The mean maternal age, BMI, neonatal birth weights and gestational age at delivery were not significantly different between the preeclamptic and normal groups. There was a significant association between preeclampsia and periodontal diseases (P ˂ 0.01). The mean number of involved teeth (P ˂ 0.001) and the mean pocket depth (P = 0.04) were higher among the preeclamptic group. Gingivitis was more frequent among the cases with mild (56.8%) compared to (31.6%) in the severe preeclamptic group (P = 0.04). Periodontitis was more prevalent among the cases with severe preeclampsia which was not statistically significant. The mean neonatal birth weight was significantly lower in the group with severe preeclampsia (P < 0.01). Conclusions: There was a significant association between preeclampsia and periodontal diseases. The number of involved teeth and pocket depth were higher among the preeclamptic mothers compared to normal pregnant women.
- انتشار مقاله: 11-10-1348
- نویسندگان: Bahia Namavar Jahromi,Rosyna Adibi,Sadaf Adibi,Leila Salarian
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Advanced Medical Sciences and Applied Technologies
- نوع مقاله: Journal Article
- کلمات کلیدی: Rat,spermatogenesis,Testis,Busulfan,Subfertility
- چکیده:
- چکیده انگلیسی: Objectives: The current study aimed at evaluating testis parameters and spermatogenesis changes in male rats administrated by different busulfan doses and time to construct a subfertile animal model by stereological methods.Materials and Methods: In the present study, 150 male Wistar rats randomly divided into 5 groups. All experimental groups were treated by different concentrations of busulfan (0.0, 2.5, 5, 10, and 15 mg/kg). Rats were sacrificed 1, 15, and 30 days after busulfan treatment. The tissue processing was done for stereological study and the results were analyzed by the one-way ANOVA followed by the Duncan test. Results: The most stereological parameters such as testes weight and volume, tubules volume density, interstitial tissue (P<0.05), and germinal epithelium (P<0.01) were significantly reduced by busulfan treatment. Also, at different busulfan doses, the number of spermatogenic cells including spermatogonia (P<0.05), spermatocyte, round and elongated spermatid, and the Sertoli and Leydig cells (P<0.01) significantly decreased, compared with those of the control group. The decline was more obvious in higher busulfan doses and time (from the day 15 to 30) (P<0.05). Conclusion: Most of testicular stereological parameters reduced during 15 days onwards after busulfan treatment in a dose-dependent manner.
- انتشار مقاله: 21-07-1396
- نویسندگان: Soghra Bahmanpour,Bahia Namavar Jahromi,Farhad Koohpeyma,Mojtaba Keshavarz,Azizollah Bakhtari
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Neonatology
- نوع مقاله: Journal Article
- کلمات کلیدی: neonate,Low birth weight,Maternal magnesium
- چکیده:
- چکیده انگلیسی: Introduction: There is a great deal of controversy regarding the effect of gestational magnesium (Mg) deficiency on fetal growth and the incidence of low birth weight (LBW) in infants. Therefore, this study aimed to delineate the possible relationship between maternal Mg level and infant LBW. Methods: This case-control study was conducted on 180 mothers in Shiraz, Iran. Fasting blood samples were obtained for magnesium after delivery. Maternal and neonatal demographic data were recorded, and the mothers were divided into two groups: the control group including mothers with normal-weight infants (≥2500 g), and the case group consisting of mothers with LBW infants (
- انتشار مقاله: 14-02-1393
- نویسندگان: Shahnaz Pourarian,Bahia Namavar Jahromi,Faranak Takmil
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: risk factors,Prevention,classification,Pathophysiology,fertilization in vitro,Ovarian hyperstimulation syndrome
- چکیده:
- چکیده انگلیسی: Ovarian hyperstimulation syndrome (OHSS) is a serious complication of ovulation induction that usually occurs after gonadotropin stimulation, followed by human chorionic gonadotropin administration, for infertility treatment. The existing knowledge about the pathophysiology, risk factors, and primary and secondary methods for the prevention of OHSS is reviewed in this manuscript. The clinical manifestations and characteristics of mild, moderate, severe, and critical forms of the syndrome are defined. The methods of handling affected cases as outpatient or in-hospital management methods as well as indications for hospitalization are summarized in this review. The clinical and biochemical routes of assessing and monitoring hospitalized patients with OHSS, various drugs and medical treatment strategies including indications for aspiration of the ascitic fluid and pleural effusion, and also rare indications for surgery are briefly explained in this article. Severe OHSS, which two decades ago was considered an iatrogenic life-threatening condition, can now be effectively prevented or managed during the early stages. An OHSS-free clinic can be established nowadays by carefully considering the endocrinology of ovulation and using appropriate and dose-adjusted pharmaceutical agents, which are summarized and discussed in this review.
- انتشار مقاله: 11-08-1395
- نویسندگان: Bahia Namavar Jahromi,Mohammad Ebrahim Parsanezhad,Zahra Shomali,Pardis Bakhshai,Mahshid Alborzi,Najmeh Moin Vaziri,Zahra Anvar
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Melatonin,Embryo,Assisted reproductive techniques,Ovarian reserve,Oocytes
- چکیده:
- چکیده انگلیسی: Diminished ovarian reserve (DOR) significantly decreases the success rate of the assisted reproductive technique (ART). In this study, we assessed the effect of melatonin on the ART outcomes in women with DOR. A double-blinded, randomized, clinical trial was performed on 80 women with DOR as a pilot study in Shiraz, between 2014 and 2015. DOR was defined as the presence of 2 of the following 3 criteria: 1) anti-Müllerian hormone ≤1, 2) folliclestimulating hormone ≥10, and 3) bilateral antral follicle count ≤6. The women received 3 mg/d melatonin or a placebo since the fifth day of one cycle prior to gonadotropin stimulation and continued the treatment up to the time of ovum pickup. The ART outcomes were compared between the groups using SPSS software. Finally, there were 32 women in the case and 34 in the placebo groups. The mean age and basal ovarian reserve test were the same between the groups. The serum estradiol level on the triggering day was significantly higher in the case group (P=0.005). The mean number of MII oocytes was higher in the case group, but the difference did not reach statistical significance. Number of the patients who had mature MII oocytes (P=0.014), top-quality embryos with grade 1 (P=0.049), and embryos with grades 1 and 2 (P=0.014) was higher among the women who received melatonin. However, the other ART outcomes were not different between the groups. The serum estradiol level was higher and more women with DOR had good-quality oocytes and embryos after receiving melatonin; however, no other outcome was different between the case and control groups.Trial Registration Number: IRCT2014041417264N1
- انتشار مقاله: 02-05-1394
- نویسندگان: Bahia Namavar Jahromi,Sara Sadeghi,Shohreh Alipour,Mohammad Ebrahim Parsanezhad,Shaghayegh Moradi Alamdarloo
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Pregnancy,Oocytes,Gonadotropins
- چکیده:
- چکیده انگلیسی: Background: Despite the large number of papers published on the efficiency of different exogenous gonadotropins, no confirmed protocol exists. Therefore, the aim of the present study was to compare the efficacy of 4 exogenous gonadotropins in IVF/ICSI cycles.Methods: This study, performed from January 2014 to May 2014, recruited 160 women referred to Ghadir Mother and Child Hospital and Dena Hospital, Shiraz, Iran. The patients underwent standard downregulation and were randomly divided into 4 groups of A, B, C, and D and were administered hMG, hFSH, rFSH, and combined sequential hFSH/rFSH, respectively. Then, the duration of stimulation, number of oocytes and embryos as well as their quality, implantation rate, biochemical and clinical pregnancy rate, and live birth rate in each group were evaluated. Results: Group D patients required significantly fewer ampoules of FSH than did the women in groups A, B, and C (P=0.004). The duration of stimulation was significantly longer in group C than in groups A and D (P=0.030). The serum estradiol level was significantly higher in group D than in groups B and C (P=0.005). A significantly higher number of large-sized follicles was observed in group D than in group B (P=0.036). Conclusion: Our data revealed no statistically significant differences in the mean oocyte number, embryo quality, clinical pregnancy rate, or live birth rate between the hMG, hFSH, rFSH, and sequential hFSH/rFSH protocols. However, several differences in the duration of stimulation, serum estradiol levels, and number of large-sized follicles were detected between the groups.Trial Registration Number: IRCT201408116541N7
- انتشار مقاله: 16-04-1394
- نویسندگان: Mohammad Ebrahim Parsanezhad,Bahia Namavar Jahromi,Solmaz Rezaee,Leila Kooshesh,Sanaz Alaee
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی: Hydatid cysts are known to occur in most organs especially in the endemic areas. However, its occurrence in uterus is extremely rare and it mostly occurs as a secondary involvement. Herein we reported on a 25-year-old woman with primary involvement of the uterus and left fallopian tube. The patient presented with a colicky abdominal pattern and fever and was admitted to the Emergency Ward.
- انتشار مقاله: 04-03-1394
- نویسندگان: Bahia Namavar Jahromi,A.R. Talei,S.Z. Tabei
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Immunology
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی: Background: Polycystic ovary syndrome (PCOS) is considered as the most common cause of female infertility that affects 4-10% of women in the reproductive age. Previous studies have shown the role of a balanced immune response in a successful pregnancy and fertility. Objective: To investigate the T helper cells type 1 (Th1) /Th2/Th17/Treg paradigms in peripheral blood of infertile PCOS compared with normal fertile women. Methods: Peripheral blood mononuclear cells (PBMCs) were isolated at the late follicular phase from 10 PCOS and 10 fertile women. PBMCs were stimulated with PMA and ionomycin in the presence of Berefeldin A as Golgi stop agent to detect intracellular cytokine production (IFN-γ, IL-17, and IL-4) from CD3+CD4+T cells population indicating T helper (Th) cells subsets by flowcytometry. Moreover, regulatory T cells were enumerated using CD25 and Foxp3 markers. Results: In this study, we report that the frequency of Th1 cells was increased compared to Th2 cells in infertile PCOS when considering Th1/Th2 ratio (P=0.05). Analysis of Th17/Th2 ratio showed a significant difference with a bias toward Th17 dominancy in PCOS (P=0.02). The proportion of CD4+CD25+Foxp3+ regulatory T cells was significantly lower in PCOS patients than that of healthy fertile women (P=0.02). Conclusion: In summary, Th1 and Th17 bias and reduction of Treg and Th2 cells as regulators of immune responses might be involved in the pathogenesis of PCOS. These results are suggestive of an altered immune response to inflammatory status in PCOS patients, likely causing some complications such as infertility in these patients.
- انتشار مقاله: 02-07-1397
- نویسندگان: Fatemeh Nasri,Mehrnoosh Doroudchi,Bahia Namavar Jahromi,Behrouz Gharesi-Fard
- مشاهده