در هنگام جستجو کلمه در قسمت عنوان میتوانید کلمات مورد جستجو را با کاراکتر (-) جدا کنید.
کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: DLBCL,Keywords: CHOP,RCHOP,clinical response evaluation
- چکیده:
- چکیده انگلیسی: Purpose: The purpose of this study was to address the question of “superiority of R-CHOP versus CHOP”, with
addition of Rituximab to CHOP, regarding survival of patients suffering from DLBCL. Patients and methods: A cohort
retrospective design was used to conduct this study in a tertiary care hospital. A total of 100 patients (50 in each group)
were randomly selected. The primary and secondary end points were EFS, OS, PFS and DFS. Kaplan Meier survival
curve analysis (log rank, Breslow and Tarone ware tests) was employed to compare probability of survival for the two
groups (CHOP/ R-CHOP). Results: The mean primary and secondary clinical indicators were estimated for each group
(EFS, 1.7; 3.09 with a p value P=0.02), (OS, 0.60; 0.43 with a p value P=0.40), (PFS, 1.73; 3.57 with a p value P=0.002), (DFS, 0.02; 0.48 with a p value of P=0.00). Conclusion:The results for differences in clinical response were statistically significant in favor of the R-CHOP group.- انتشار مقاله: 15-09-1395
- نویسندگان: Ayesha Tariq,Muhammad Tahir Aziz,Yasir Mehmood,Shehroz Ali Asghar,Azhar Khurshid
- مشاهده