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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: colposcopy,cervical intraepithelial neoplasia,loop electrosurgical excision procedure
- چکیده:
- چکیده انگلیسی: Objective: To determine predictors of having cervical intraepithelial neoplasia (CIN) 1 or less in loop
electrosurgical excision procedure (LEEP) specimens of patients with colposcopic directed biopsy-confirmed CIN 2-3.
Methods: Two hundred and eighty patients with colposcopic directed biopsy-confirmed CIN 2-3 who subsequently
underwent LEEP were enrolled in the retrospective study. Related clinical data were collected to determine the predictors of
CIN 1 or less in LEEP specimens. Results: CIN 1 or less in LEEP specimens was found in 71 (25.4%) of 280 patients.
Multivariate logistic regression analyses demonstrated that nulliparity [OR (95% CI) = 3.375 (1.245-9.150)], low
grade Papanicolaou (Pap) results [OR (95% CI) = 6.410 (2.877-14.280)] and low grade colposcopic impression
[OR (95% CI) = 16.506 (5.844-46.632)] were significant risk factors of having CIN 1 or less in LEEP specimens. Neither
persistent nor recurrent CIN 2-3 was detected in 71 patients who had CIN 1 or less in LEEP specimens. However,
persistent or recurrent CIN 2-3 developed in 3 out of 209 (1.4%) patients with CIN 2-3 found in LEEP specimens.
Conclusion: Approximately 25% of patients with CIN 2-3 in colposcopic directed biopsy specimens had CIN 1 or less
found in LEEP specimens. Predicting factors of having CIN 1 or less in LEEP specimens were nulliparity, low grade
Pap results and low grade colposcopic impression.- انتشار مقاله: 13-06-1397
- نویسندگان: Yenrudee Poomtavorn,Chamnan Tanprasertkul,Araya Sammor,Komsun Suwannarurk,Yuthadej Thaweekul
- مشاهده