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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Iranian Journal of Neonatology
- نوع مقاله: Journal Article
- کلمات کلیدی: Screening,Glucometer,Neonatal hypoglycemia
- چکیده:
- چکیده انگلیسی: Background: Hypoglycemia is one of the most common neonatal disorders, associated with severe complications. There has been a great deal of controversy regarding the definition and screening of hypoglycemia. Therefore, in this study, we aimed to determine a cut-off value for blood glucose level in glucometer readings.
Methods: This cross-sectional study was conducted on 238 newborns at risk of hypoglycemia, admitted to Baqiyatallah Hospital of Tehran, Iran in 2012; the subjects were selected via simple sampling. After obtaining informed consents from the newborns’ parents, 1 cc blood samples were sent to the laboratory for measuring the blood glucose level. Moreover, venous blood samples, as well as heel-stick blood samples, were obtained for glucometer measurements. Blood glucose measurements were used to determine the cut-off value by the receiver operating characteristic (ROC) curve and make comparisons with the diagnostic criteria for hypoglycemia in the literature.
Results: A total of 238 infants with the mean weight of 2869±821.9 g were enrolled in this study. The mean (±SD) blood glucose levels were 65.1±22.9, 82.9±24.7, and 84.4±24.8 mg/dl, based on the standard laboratory method, glucometer reading of venous blood samples, and glucometer reading of heel-stick capillary blood samples, respectively. The optimal cut-off point for hypoglycemia was determined as 65 mg/dl, using glucometer-based assessment of heel-stick blood samples.
Conclusion: The significant difference in blood glucose levels measured by the laboratory method and outpatient glucometer readings highlights the importance of a cut-off value for rapid assessment and control of blood glucose and timely detection of hypoglycemia. In fact, the cut-off value introduced in the present study could facilitate such measurements.- انتشار مقاله: 01-01-1395
- نویسندگان: Mohammad Torkaman,Gholamreza Bagheri,Ahmad Ahmadi,Amin Saburi
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Cytokines,Bronchiolitis,Mustard Gas,Interleukin-6
- چکیده:
- چکیده انگلیسی: Diverse studies suggest that interleukin-6 (IL6), as a member of cytokines family, has a major role in inflammatory processes of airways and lungs. In this study, an attempt was made to determine the serum level of IL6 in sulfur mustard (SM) injured patients and its comparison with controls. The measured IL6 mean level in patients with chemical injuries (0.76±0.3 ng/ml) was significantly higher than the control group’s mean level (0.34±0.12 ng/ml). Furthermore, patients with moderate to severe symptoms had a serum level of (0.95±0.92 ng/ml) which was significantly higher than mild (0.47±0.54) and control (0.34±0.12) groups.The outcome of this research program demonstrates that an increase in serum level of IL6 can have a role in pulmonary complications of SM, similar to other well defined pulmonary diseases. However, further studies are required to clarify the role and mechanism of IL6 in such patients.
- انتشار مقاله: 10-04-1393
- نویسندگان: Majid Shohrati,Ali Amini-Harandi,Bita Najafian,Amin Saburi,Mostafa Ghanei
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Travel Medicine and Global Health
- نوع مقاله: Journal Article
- کلمات کلیدی: Pediatrics,Diabetes Mellitus,Pneumonia,coronavirus
- چکیده:
- چکیده انگلیسی: Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), or COVID-19, is a pandemic infectious disease involved all over the world. Its mortality, especially in cases with additional co-morbidities, is so high that is has attracted the attention of the world. Diabetes mellitus is known as one of its risk factors for mortality.
Case Presentation: A unique case of pediatrics COVID-19 who presented with diabetic ketoacidosis (DKA) is reported in this manuscript as the first presentation. He presented with abdominal pain, nausea, and vomiting. RT-PCR test for COVID-19 via nasal swab was performed, and a positive diagnosis was obtained. Chest CT scan confirmed the diagnosis with multifocal bilateral patchy consolidation. Case was discharged after usual treatment of COVID-19.
Conclusion: In pediatrics, this disease can be subtle and have a confusion presentation, but it should be controlled to avoid spread of the disease.- انتشار مقاله: 29-02-1399
- نویسندگان: Shahin Jafarpour,Masoumeh Abedini,Fatemeh Eghbal,Amin Saburi
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Travel Medicine and Global Health
- نوع مقاله: Journal Article
- کلمات کلیدی: Chest,Trauma,fracture,Chest X-Ray
- چکیده:
- چکیده انگلیسی: Introduction: Currently, trauma is the main reason of mortality among 1-44 years old people and the third common reason of death throughout all ages. The aim of this study is to examine the radiographic findings in chest trauma patients referring to the Imam Reza Hospital in Birjand during the years of 2013-2014.
Methods: The patients meeting the criteria for the entrance to the study were examined and the frequency of radiographic findings in conventional x-ray and CT scan in the mentioned patients was recorded. After data collection, they were introduced to the SPSS 15 software, in which descriptive statistics and suitable statistical tests were analyzed at α=0.05.
Results: Based on the results of this study, the most common radiologic finding in chest trauma patients was rib fracture (21.9%). Other radiologic findings, in order of prevalence, were: clavicle fracture (11.7%), pneumothorax (9.3%), spine fracture (7.6%), Hemothorax (6.3%), increased heart shadow (2.2%), wide mediastinum (1.9%), sternum fracture (1.7%), and pleural effusion (1.2%), respectively. There was a significant relationship between radiologic findings and the type of trauma (P<0.05).
Conclusion: We found that clavicle fracture, pneumothorax, spine fracture, and hemothorax are the most common findings followings in chest trauma. Based on the results, as the type of trauma (penetrating or blunt) can have a direct relationship with its resulting pathology, modification of sociocultural structures should be considered in this regard.- انتشار مقاله: 11-01-1394
- نویسندگان: Mahyar Mohammadi-Fard,Mohammad-Mahdi Khalesi,Amin Saburi,Kourosh Javdan,Ghodratollah Naseh
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Travel Medicine and Global Health
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی:
- انتشار مقاله: 12-02-1394
- نویسندگان: Fatemeh Eghbal,Amin Saburi
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Travel Medicine and Global Health
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی:
- انتشار مقاله: 28-03-1393
- نویسندگان: Mahyar Mohammadi-Fard,Amin Saburi
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Travel Medicine and Global Health
- نوع مقاله: Journal Article
- کلمات کلیدی: Osteoporosis,Calcitonin,Bone Density,Biological Markers
- چکیده:
- چکیده انگلیسی: Introduction: Various therapeutic options such as Calcitonin are suggested for patients with low bone density. However, the efficacy remains uncertain in all patients. C-telopeptide of type I collagen (CTx) is the authentic bone marker which is recently used to assess the bone turnover. This study aimed at revealing the therapeutic effects of Calcitonin on osteopenic women via serum CTx and assessment of other biochemical markers.
Methods: we conducted a before-after clinical trial on menopause women with low bone mineral density (bone mineral density score less than 1.5 SD of peak bone mass) attending Baqiyatallah hospital clinic. They received 200 IU Calcitonin nasal spray, calcium (1000 mg) and vitamin D (400 IU). Then the serum CTx and other laboratory parameters were compared after a 6 months treatment. The data was analyzed using SPSS ver.16, paired T-test and regression model.
Results: The study population included 115 menopause women with the mean age of 58.75 ± 8.15 years. The CTx amount decreased significantly compared with that of the baseline level (3.203 ± 2.24 vs. 2.497 ± 1.657 Pmol/lit, P <0.001). Also, Bone Mineral Densitometry of spine increased significantly from 0.834±0.112 to 0.852±0.122 (P =0.003). Serum levels of PTH, Ca, AST, ALT and alkaline phosphatase total had also changed insignificantly (P >0.05).
Conclusion: Nasal spray of Calcitonin could be effective on the progression of osteoporosis by decreasing bone tissue turnover and improving the bone density. Further controlled-studies with a larger sample size and a longer duration of follow up are recommended.- انتشار مقاله: 13-04-1393
- نویسندگان: Bita Najafian,Majid Shohrati,Amin Saburi,Zahra Abbasi,Gholam-Hossein Alishiri,Noushin Bayat
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Travel Medicine and Global Health
- نوع مقاله: Journal Article
- کلمات کلیدی: Susceptibility,Meropenem,Gram-Negative Rods,Imipenem
- چکیده:
- چکیده انگلیسی: Introduction: Nosocomial infections are responsible for the much of the morbidity and mortality found in hospitals. The present study was conducted on 70 bacterial strains isolated from hospitalized patients in various medical units of Baqiyatallah Hospital in Tehran, Iran during a period of 12 months from; March to February 2009.
Methods: The bacterial sensitivity for meropenem and imipenem was evaluated using the E-test and explanations of the MIC values. All patients were included in this study that had been hospitalized with no signs and symptoms of infection within the first 48 hours of hospitalization and began presenting signs and symptoms of infection after 48 hours of hospitalization.
Results: Resistance to meropenem and imipenem was confirmed with E-test (AB Biodisk, Sweden) and disc diffusion methods. Meropenem and imipenem were active against 61 (64.2%) and 62(65.2%) strains, respectively, of the 95 ESBL positive strains.
Conclusion: The activity of meropenem or imipenem against gram negative ESBL-positive bacilli is decreasing rapidly but even so these antibiotics are effective against nosocomial multiresistant organisms.- انتشار مقاله: 17-09-1392
- نویسندگان: Nematollah Jonidi Jafari,Morteza Izadi,Massoud Hajia,Mahdi Qorbanalizadgan,Amin Saburi
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی: Poisoning,Gastroesophageal Reflux,Mustard Gas,Bronchiolitis Obliterans,Radionuclide Imaging
- چکیده:
- چکیده انگلیسی: Background:Gastroesophageal reflux disease (GERD) prevalence in patients with sulfur mustard (SM)-induced bronchiolitis obliterans (BO) is higher than exposed cases with mild lung injuries. In this study, we aimed to evaluate the prevalence of microaspirations using nuclear scintiscan among BO patients with SM exposure. Methods: This was a prospective cross-sectional study conducted on patients with SM-induced BO and pulmonary symptom exacerbation referred to the Baqiyatallah Hospital, Tehran, Iran during the year 2009. Following the endoscopy-based diagnosis of GERD by a gastroenterologist, anti-reflux medications were withdrawn for 72 hours and then the patients underwent nuclear scintigraphy scan following 12 hour ingestion of fat containing food as radionuclide dinner. High resolution computed tomography (HRCT), spirometry and bronchoscopy were also performed for all patients. Results: In this study, 39 patients (94.9% men) with mean (± SD) age of 45.1 ± 6.2 years were enrolled. The most common clinical complaints of the patients were thick sputum (97.4%) and dyspepsia (94.7%), followed by chest tightness (89.7%), nocturnal cough (82.1%), and nocturnal dyspnea (66.7%). In HRCT, air-trapping was the most common pulmonary finding (92.1%). In spirometry, mean (±SD) FEV1 and FEV1/FVC were 52.7 ± 22.4% and 70.4 ± 13.9%, respectively. In bronchoscopy, the most common finding was airway remodeling (62.2%), followed by false vocal cord hypertrophy (24.3%). In scintigraphic imaging, only 1 patient had a remarkable finding, in whom, the radionuclide material was seen in the pharynx (proximal GERD), but did not produce marked microaspiration of gastric substances into the airways. Conclusion:Although previous reports demonstrated high prevalence of GERD and microaspiration in patients with SM-induced BO, we did not find remarkable evidence for microaspiration in scintiscan in patients included in this study.
- انتشار مقاله: 22-04-1394
- نویسندگان: Ali Ghazvini,Ashraf Karbasi,Amin Saburi,Rasoul Aliannejad,Mostafa Ghanei
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی: occupational exposure,Spirometry,Lung Diseases,Solvents,Trinitrotoluene
- چکیده:
- چکیده انگلیسی: Background: Trinitrotoluene (TNT) is one of the most well-known and oldest explosive agents. In the recent decade, bioenvironmental, biochemical, and biological effects of TNT exposure have been more in the spotlight. In this study, we aimed to evaluate spirometric parameters in workers of a TNT factory exposed to TNT and other related fumes and dusts compared with the unexposed controls.
Methods: In this case-control study, spirometry was done for TNT factory workers (cases) and matched healthy controls, and their results were compared with each other. Matched controls were selected from workers who worked in the same geographic area without any history of TNT or other chemical materials exposure. Spirometric studies were done during the early hours of day.
Results: Overall, 90 subjects (47 TNT exposed cases and 43 controls) were included. The two groups showed no significant difference in demographic characteristics and smoking habits. In spirometry, it was found that the cases had significantly lower forced vital capacity (91.4 ± 13.7% vs. 100.2 ± 13.0%, P = 0.002), forced expiratory volume in 1 second (98.0 ± 14.9% vs. 104.7 ± 12.5%, P = 0.024) and peak expiratory flow (98.4 ± 17.3% vs. 107.9 ± 21.7%, P = 0.025) compared with controls. According to spirometric findings, 10 cases (21.3%) and no controls had restrictive pattern, which means TNT factory workers had 1.27 (CI: 1.09-1.47, P = 0.001) fold risk for development of restrictive patterns.
Conclusion: Chronic exposure to TNT or prolonged working in TNT factories may predispose the workers to respiratory disorders. In addition to regular screening programs, preventive measures and devices should be considered for TNT factory workers to reduce the harms.- انتشار مقاله: 15-03-1393
- نویسندگان: Majid Shohrati,Bita Najafian,Amin Saburi,Ensiyeh Vahedi,Mostafa Ghanei
- مشاهده