در هنگام جستجو کلمه در قسمت عنوان میتوانید کلمات مورد جستجو را با کاراکتر (-) جدا کنید.
کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Journal of Plant Physiology and Breeding
- نوع مقاله: Journal Article
- کلمات کلیدی: Bentazon,Electron transport,Chlorophyll a fluorescence,JIP-test,Nicosulfuron,Spiny cocklebur
- چکیده: فاز نوری گیاه زردینه خاردار (Xanthium spinosum) توسط آزمن JIP در زمانهای مختلف (12، 36، 60 و 84 ساعت) بعد از کاربرد علفکشهای نیکوسولفورون و بنتازون مورد مطالعه قرار گرفت. نتایج نشان داد کاربرد نیکوسولفورون تاثیری روی بسیاری از پارامترهای فلورسانس کلروفیل a نداشت. اما، کاربرد بنتازون بطور معنیداری با افزایش فلورسانس حداقل و کاهش فلورسانس حداکثر، فلورسانس متغیر، فعالیت کمپلکس تجزیه کننده آب در بخش دهنده الکترون فتوسیستم II و بویژه حداکثر عملکرد کوانتومی فتوشیمیایی فتوسیستم II، باعث کاهش فعالیت فتوسیستم II گردید. کاربرد بنتازون به دلیل افزایش جریان نوری جذب شده در هر مرکز واکنش و کاهش کارایی انتقال الکترونهای به دام افتاده از مراکز واکنش به کوئینون A و نیز کاهش عملکرد کوانتومی انتقال الکترون از کوئینون A به پلاستوکوئینون، روی بخش دهنده الکترون فتوسیستم II به مراتب تاثیرگذارتر از بخش گیرنده الکترون آن بود. کاهش خاصیت حیاتی فتوسنتزی دستگاه فتوسنتزی توسط بنتازون، کلروفیلهای مراکز واکنش فتوسیستم II، حداکثر عملکرد کوانتومی فتوشیمیایی اولیه و عملکرد کوانتومی برای انتقال الکترون را تحت تاثیر قرار میدهد. در بسیاری موارد، اثرات بازدارنده بنتازون روی فتوسیستم II، 36 ساعت بعد از کاربرد علفکش گزارش شد. تیمار بنتازون سرعت زنجیره انتقال الکترون را کاهش و در پی آن سرعت بازانتشار فتوشیمیایی انرژی نورانی آنتنهای برانگیخته را افزایش میدهد.
- چکیده انگلیسی: The photosynthetic light phase of spiny cocklebur (Xanthium spinosum L.) plant was studied by JIP-test at different times (12, 36, 60 and 84 hours) after nicosulfuron and bentazon herbicides application. Results indicated that application of nicosulfuron had no effect on the most of chlorophyll a fluorescence parameters. But, application of bentazon significantly decreased photosystem II (PSII) activity via increasing minimum fluorescence and decreasing maximum fluorescence, variable fluorescence, the activity of the water-splitting complex on the donor side of PSII and especially maximum quantum yield of PSII photochemistry. Application of bentazon had a greater effect on the donor site than on the acceptor site of PSII by increasing absorption flux per reaction center and decreasing the values of efficiency through which the trapped electrons from RCs continue beyond QA and also by reduction of quantum yield for electron transport from QA- to PQ. Reduction in photosynthesis relative vitality (PI) by application of bentazon negatively affected reaction centers per PSII antenna chlorophyll, maximum quantum yield for primary photochemistry and the quantum yield for electron transport. In most case, the inhibitory effects of bentazon on PSII activity were recorded at 36 hours after herbicide application. Bentazon treatment decreased the rate of the electron transport chain and this was supported by increasing the photochemical de-excitation rate constant in the excited antennae of energy fluxes for photochemistry.
- انتشار مقاله: 03-08-1398
- نویسندگان: Sirous Hassannejad,Soheila Porheidarghafarbi,Ramin Lotfi
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Immunology
- نوع مقاله: Journal Article
- کلمات کلیدی: Cytotoxicity,Hyperthermia,Liposarcoma,NKG2D Ligands,SW-872
- چکیده:
- چکیده انگلیسی: Background: Although there is convincing data in support of the effectiveness of hyperthermia in tumor therapy, the molecular mechanisms underlying the clinical effects of hyperthermia are still poorly understood.
Objective: To investigate natural killer (NK) cell cytotoxicity against heat-treated SW-872 and HeLa tumor cell lines.
Methods: NKG2D ligands and HLA class I transcription were examined using quantitative real-time PCR in treated tumor cell lines at 0, 2, 4, 6 and 12 h following thermal treatment at 39C and 42C for 1 h. The expression of MICA/B, ULBP1 and ULBP2 were also determined by flow cytometry. NK92-MI cytotoxic activity against heat-treated target cell lines was assessed by LDH release as well as annexin-V and 7-AAD assays.
Results: Our results showed that heat treatment at 39C improved the cytolytic activity of NK cells against SW-872 cells without increasing NKG2D ligand concentration or decreasing HLA class I levels.
Conclusion: The observed increase in the cytotoxicity of NK cells against SW-872 cells after hyperthermia does not coincide with changes in MICA/B, ULBP1 and ULBP2 ligands of NKG2, however, the expression of other ligands in target cells may have made the cells susceptible to the cytotoxic effect of NK cells.- انتشار مقاله: 15-05-1395
- نویسندگان: Shirin Farjadian,Marzie Norouzian,Vahid Younesi,Azin Ebrahimpour,Ramin Lotfi
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Immunology
- نوع مقاله: Journal Article
- کلمات کلیدی: Hyperthermia,Liposarcoma,MICA/B
- چکیده:
- چکیده انگلیسی: Background: A possible mechanism by which hyperthermia enhances tumor immunogenicity is the induction of NKG2D ligands on tumor cells. Although the expression of MHC class I chain-related protein A and B (MICA/B) has previously been reported in different carcinomas, there is no information about MICA/B expression in liposarcomas.
Objective: To investigate MICA/B induction in a human liposarcoma cell line (SW-872) after thermotherapy.
Methods: SW-872 and HeLa cell lines were subjected to thermal stress for 1 h at 42, 44 and 46C, and after 2, 4 and 6 h of incubation at 37C, MICA/B expression was assessed at the mRNA and protein levels.
Results: Despite high levels of MICA/B transcripts in SW-872 cells at baseline, the expression of these genes decreased significantly at both the mRNA and protein levels after almost all thermal treatments.
Conclusion: Our data conclude that thermotherapy under 42-46°C had no effect on MICA/B induction on SW-872 liposarcoma cell line but the effects of fever-range temperatures remain to be tested on this cell line.- انتشار مقاله: 15-05-1395
- نویسندگان: Shirin Farjadian,Shahrzad Rahimifar,Nasrollah Erfani,Ramin Lotfi
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Advanced Biological and Biomedical Research
- نوع مقاله: Journal Article
- کلمات کلیدی: Entrepreneurial spirit,Wood and paper industry,Educational and academic factors
- چکیده:
- چکیده انگلیسی:
The purpose of this paper is to explore the influential factors on entrepreneurial spirit of wood and paper industries students in two universities, namely Agriculture and natural resources faculty of Tehran University and Shahid Rajaiee teacher training University. A sample of 100 students were selected from a target population of 572 students using the Cochran formula. The respondents were asked to provide their answers to a standardized questionnaire. Results indicated that from the students’ perspective such factors as motivation, providence and achievement propensity had the greatest impact on entrepreneurial spirit of the respondents whilst factors like internal control, exception ability and having systematic attitude had the least influence. Moreover concerning the effect of educational and academic factors on entrepreneurial spirit, the most effective items were respectively favorable access to computer and internet and learned and efficient instructors whereas the least effective items considered were degree orientation, students’ apprenticeships in executive environments and education at the university. The findings showed a significant positive relation at the significance level of 0.05 between the level of education and age with the creation of entrepreneurial spirit amongst students. Furthermore a significant positive relation was observed between educational and academic factors, propensity to achievement, risk taking and ambiguity toleration, control source and family with entrepreneurial spirit at the significance level of 0.01. Also the results of multiple regression analysis showed that 79.7%of entrepreneurial spirit (the dependent variable) variance was explained by such independent variables as educational and academic factors, achievement propensity, being innovative, risk taking and ambiguity toleration, control source and family.- انتشار مقاله: 02-08-1397
- نویسندگان: Feizollah Monavari Fard,Seyed Alireza Dehghan,Amine Lotfian,Laleh Salehi
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Advanced Biological and Biomedical Research
- نوع مقاله: Journal Article
- کلمات کلیدی: Entrepreneurial spirit,Wood and paper industry,Educational and academic factors
- چکیده:
- چکیده انگلیسی: The purpose of this paper is to explore the influential factors on entrepreneurial spirit of wood and paper industries students in two universities, namely Agriculture and natural resources faculty of Tehran University and Shahid Rajaiee teacher training University. A sample of 100 students were selected from a target population of 572 students using the Cochran formula. The respondents were asked to provide their answers to a standardized questionnaire. Results indicated that from the students’ perspective such factors as motivation, providence and achievement propensity had the greatest impact on entrepreneurial spirit of the respondents whilst factors like internal control, exception ability and having systematic attitude had the least influence. Moreover concerning the effect of educational and academic factors on entrepreneurial spirit, the most effective items were respectively favorable access to computer and internet and learned and efficient instructors whereas the least effective items considered were degree orientation, students’ apprenticeships in executive environments and education at the university. The findings showed a significant positive relation at the significance level of 0.05 between the level of education and age with the creation of entrepreneurial spirit amongst students. Furthermore a significant positive relation was observed between educational and academic factors, propensity to achievement, risk taking and ambiguity toleration, control source and family with entrepreneurial spirit at the significance level of 0.01. Also the results of multiple regression analysis showed that 79.7%of entrepreneurial spirit (the dependent variable) variance was explained by such independent variables as educational and academic factors, achievement propensity, being innovative, risk taking and ambiguity toleration, control source and family.
- انتشار مقاله: 28-04-1393
- نویسندگان: Feizollah Monavari Fard,Seyed Alireza Dehghan,Amine Lotfian,Laleh Salehi
- مشاهده
- جایگاه : پژوهشی
- مجله: Advanced Herbal Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Gastric ulcers,Medicinal plant,HPLC,Second metabolism
- چکیده:
- چکیده انگلیسی: Background and aims: Medicinal plants are a valuable resource for flavonoids extraction. Prosopis fracta is one of the plants with medicinal properties. Prosopis fracta was found in abundance in southern regions in Iran. Coersetin is medicinal substance found in the fruit of this plant. Quercetin is used in treatment of cancer and viral infections. This study was conducted to determine the Quercetin flavonoid in Prosopis fracta samples in different regions of Khuzestan. Methods: The Prosopis fracta fruit collected from different regions of Khuzestan (Susangerd, Ahvaz, Abadan, Mollasani, Behbahan and Ramhormoz). The beads were isolated from the fruit. Shell and the flesh were dried in an Oven. The dried materials were mixed and flavonoids extracted with a suitable solvent. The extract was injected into the High Performance Liquid Chromatography (HPLC) system. Then, the compound, Quercetin quantity and standard peak in each sample have been determined. Results: Based on the results, the Susangerd samples (0.0033 mg/ml) and Abadan (0.0008 mg/ml) have maximum and minimum levels of Quercetin flavonoid, respectively. Conclusions: Quercetin flavonoid extracted from Prosopis farcta fruits of Susangerd is richer than other regions of Khuzestan province. Therefore, it is recommended to use the Prosopis fracta fruit grown in Susangerd for extraction of the Quercetin flavonoid.
- انتشار مقاله: 26-04-1393
- نویسندگان: Fatemeh Direkvand-Moghadam,Vahid Ghasemi-Seyed,Ali-Reza Abdali-Mashhadi,Amin Lotfi,Ashraf Direkvand-Moghadam,Ali Delpisheh
- مشاهده
- جایگاه : پژوهشی
- مجله: Advanced Herbal Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Gastric ulcers,Medicinal plant,HPLC,Second metabolism
- چکیده:
- چکیده انگلیسی: Background and aims: Medicinal plants are a valuable resource for flavonoids extraction. Prosopis fracta is one of the plants with medicinal properties. Prosopis fracta was found in abundance in southern regions in Iran. Coersetin is medicinal substance found in the fruit of this plant. Quercetin is used in treatment of cancer and viral infections. This study was conducted to determine the Quercetin flavonoid in Prosopis fracta samples in different regions of Khuzestan. Methods: The Prosopis fracta fruit collected from different regions of Khuzestan (Susangerd, Ahvaz, Abadan, Mollasani, Behbahan and Ramhormoz). The beads were isolated from the fruit. Shell and the flesh were dried in an Oven. The dried materials were mixed and flavonoids extracted with a suitable solvent. The extract was injected into the High Performance Liquid Chromatography (HPLC) system. Then, the compound, Quercetin quantity and standard peak in each sample have been determined. Results: Based on the results, the Susangerd samples (0.0033 mg/ml) and Abadan (0.0008 mg/ml) have maximum and minimum levels of Quercetin flavonoid, respectively. Conclusions: Quercetin flavonoid extracted from Prosopis farcta fruits of Susangerd is richer than other regions of Khuzestan province. Therefore, it is recommended to use the Prosopis fracta fruit grown in Susangerd for extraction of the Quercetin flavonoid.
- انتشار مقاله: 26-04-1393
- نویسندگان: Fatemeh Direkvand-Moghadam,Vahid Ghasemi-Seyed,Ali-Reza Abdali-Mashhadi,Amin Lotfi,Ashraf Direkvand-Moghadam,Ali Delpisheh
- مشاهده