در هنگام جستجو کلمه در قسمت عنوان میتوانید کلمات مورد جستجو را با کاراکتر (-) جدا کنید.
کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Interdisciplinary Journal of Virtual Learning in Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Education,Technology,Learning,E-Learning,Learning Management System,Content Management System
- چکیده:
- چکیده انگلیسی: Emerging technologies of information and communications have been severely affected the society particularly impact on educational systems and new directions ( E-Learning). E-learning rapidly become a significant issue and its place has stabilized in the educational structure of many countries and now learning modern methods being influence to all educational and commercial institutions of the world. Currently e-learning has many changes in higher education and introduced as a new model of a modern educational system and changed learning concepts in the past . In this review paper, after introduction of e-learning system and its main components including CMS and LMS, the world 's newest learning management systems has been studied . Finally the latest version of the Blackboard learning management system is presented .
- انتشار مقاله: 11-10-1398
- نویسندگان: Alireza Mirzaei,Fereidoon Shabani Nia
- مشاهده
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Surgery,Conservative treatment,Intramuscular hemangiomas
- چکیده:
- چکیده انگلیسی: Background: Conservative management is generally the primary treatment for intramuscular hemangimas. However,
many patients will require surgery later in their life, after suffering a long period of pain. We aimed to evaluate the
oncologic and functional outcomes of surgery as the initial treatment of single-muscle hemangiomas.
Methods: Medical profiles of 17 patients with hemangiomas of vastus medialis for whom surgery was selected as
the initial treatment were reviewed. The indication for surgery was a bothersome pain. Postoperative muscle strength
was assessed with manual muscle testing (range 0-5). The postoperative pain was measured by a visual analog scale
(VAS) for pain (range 0-10). Lyshölm-Tegner knee scoring scale was used for the evaluation of knee function.
Results: The mean age of the patients was 25.9±8.6 years. Surgery was performed as wide resection in 13 cases and
as marginal resection in 4 cases. At a mean follow-up of 55.76±30 months, two local recurrences (11.8%) were observed.
At the last evaluation session, muscle strength grade was 5/5 in 13 patients and 4/5 in four patients. Postoperative
pain was noticed in four patients (VAS=1). Knee function was excellent in 13 patients and good in four patients. Both
of the local recurrences occurred in marginally resected lesions. Three out of four cases with reduced muscle strength,
postoperative pain, and reduced function were also treated with marginal resection.
Conclusion: If a wide surgical margin is achievable without compromising the limb function, surgical resection could
be considered as the primary choice of treatment for single-muscle hemangiomas.
Level of evidence: IV- انتشار مقاله: 05-03-1398
- نویسندگان: Khodamorad Jamshidi,Milad Haji Agha Bozorgi,Hassan Assad Kassir,Alireza Mirzaei
- مشاهده
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Giant cell tumor of bone,epidemiologic characteristics,Functional outcome,oncologic outcome
- چکیده:
- چکیده انگلیسی: Background: Giant cell tumor of bone (GCTB) is a locally aggressive lesion with an unpredictable behavior. Herein,
the aim of this study was to evaluate the epidemiological characteristics, as well as clinical and functional outcomes of
GCTB in a relatively large series of patients.
Methods: Patients with the diagnosis of GCTB were included in this retrospective study. Whenever the preservation
of the articular surface was possible, surgical options included extended curettage; otherwise, wide resection was
implemented. In case of extended curettage, the cavity was filled with cement or bone graft. In addition, the functional
and oncologic outcomes of these surgical strategies were compared. The functional outcome of the patients was
assessed using the Musculoskeletal Tumor Society (MSTS) scoring system.
Results: A total of 120 GCTB patients, including 55 males (45.8%) and 65 females (54.2%), were evaluated. The
three involved locations with highest frequency included distal femur (26%), distal radius (22%), and proximal tibia
(19%). At a mean follow-up of 125.5±49.2 months, two pulmonary metastases (1.6%) and 12 (10%) local recurrences
were observed. In addition, 6 out of 12 (50%) local recurrences occurred in distal radius (P=0.04). The recurrence rate
was significantly higher in extended curettage than in wide resection (P=0.05), and the same pattern was observed
for allograft, compared to cement filling (P=0.05). The mean MSTS scores for extended curettage and wide resection
were 94.7 and 89.1, respectively (P=0.04). Furthermore, the mean MSTS scores for bone graft filling and cement
augmentation were obtained as 96 and 93.1, respectively (P=0.07).
Conclusion: Based on the findings, wide resection of GCTB was associated with superior oncologic outcome, as well
as inferior functional outcome. In extended curettage, cement augmentation resulted in superior oncologic outcome
when compared with allograft filling.
Level of evidence: IV- انتشار مقاله: 03-07-1397
- نویسندگان: Khodamorad Jamshidi,Amin Karimi,Alireza Mirzaei
- مشاهده
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Outcome,Radiological spinopelvic parameters,Sagittal imbalance,Spinal osteotomy
- چکیده:
- چکیده انگلیسی: Background: Sagittal imbalance is known as the main radiographic driver of disability in adult spinal deformity (ASD).
In this study, the association of radiological spinopelvic parameters and clinical outcomes was evaluated following the
corrective surgery of sagittal imbalance, in order to explore the predictive ability of each parameter.
Methods: A total of 23 patients, who underwent corrective osteotomy for restoration of sagittal balance, were included in
this study. The mean follow-up period of the patients was 15.5±2.1, ranging from 12 to 18 months. Pre- and postoperative
radiological parameters including pelvic tilt (PT), sagittal vertical axis (SVA) and pelvic incidence minus lumbar lordosis
(PI-LL) were assessed for each patient. Clinical outcomes were evaluated using Oswestry disability Index (ODI).
Results: The mean ODI improved 32% following the corrective osteotomy of sagittal imbalance. Postoperative ODI
was significantly correlated with all preoperative radiological parameters (r=0.608, P=0.002 for PI-LL; r=0.483, P=0.01
for PT; and r=0.464, P=0.02 for SVA). ODI improvement was significantly correlated with PI-LL and SVA change (r=536,
P=0.008 and r=416, P=0.04, respectively), but not with PT change (r=247, P=0.25). The outcome was better in pedicle
subtraction osteotomy (PSO) compared to Smith-Petersen Osteotomy (SPO).
Conclusion: Surgical correction of sagittal imbalance could limit the amount of disability caused by this misalignment.
According to our results, while all the spinopelvic parameters could be used in the prediction of the outcomes of
corrective surgery of sagittal imbalance, PI-LL was the most informative parameter and more attention should be
devoted to this parameter.- انتشار مقاله: 11-07-1396
- نویسندگان: Hasan Ghandhari,Maryam Ameri Mahabadi,Farshad Nikouei,Saeed Sabbaghan,Abouzar Azizi,Alireza Mirzaei,Behrooz Givehchian
- مشاهده
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Giant cell tumor of bone,epidemiologic characteristics,Functional outcome,oncologic outcome
- چکیده:
- چکیده انگلیسی: Background: Giant cell tumor of bone (GCTB) is a locally aggressive lesion with an unpredictable behavior. Herein,
the aim of this study was to evaluate the epidemiological characteristics, as well as clinical and functional outcomes of
GCTB in a relatively large series of patients.
Methods: Patients with the diagnosis of GCTB were included in this retrospective study. Whenever the preservation
of the articular surface was possible, surgical options included extended curettage; otherwise, wide resection was
implemented. In case of extended curettage, the cavity was filled with cement or bone graft. In addition, the functional
and oncologic outcomes of these surgical strategies were compared. The functional outcome of the patients was
assessed using the Musculoskeletal Tumor Society (MSTS) scoring system.
Results: A total of 120 GCTB patients, including 55 males (45.8%) and 65 females (54.2%), were evaluated. The
three involved locations with highest frequency included distal femur (26%), distal radius (22%), and proximal tibia
(19%). At a mean follow-up of 125.5±49.2 months, two pulmonary metastases (1.6%) and 12 (10%) local recurrences
were observed. In addition, 6 out of 12 (50%) local recurrences occurred in distal radius (P=0.04). The recurrence rate
was significantly higher in extended curettage than in wide resection (P=0.05), and the same pattern was observed
for allograft, compared to cement filling (P=0.05). The mean MSTS scores for extended curettage and wide resection
were 94.7 and 89.1, respectively (P=0.04). Furthermore, the mean MSTS scores for bone graft filling and cement
augmentation were obtained as 96 and 93.1, respectively (P=0.07).
Conclusion: Based on the findings, wide resection of GCTB was associated with superior oncologic outcome, as well
as inferior functional outcome. In extended curettage, cement augmentation resulted in superior oncologic outcome
when compared with allograft filling.
Level of evidence: IV- انتشار مقاله: 03-07-1397
- نویسندگان: Khodamorad Jamshidi,Amin Karimi,Alireza Mirzaei
- مشاهده
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Outcome,Radiological spinopelvic parameters,Sagittal imbalance,Spinal osteotomy
- چکیده:
- چکیده انگلیسی: Background: Sagittal imbalance is known as the main radiographic driver of disability in adult spinal deformity (ASD).
In this study, the association of radiological spinopelvic parameters and clinical outcomes was evaluated following the
corrective surgery of sagittal imbalance, in order to explore the predictive ability of each parameter.
Methods: A total of 23 patients, who underwent corrective osteotomy for restoration of sagittal balance, were included in
this study. The mean follow-up period of the patients was 15.5±2.1, ranging from 12 to 18 months. Pre- and postoperative
radiological parameters including pelvic tilt (PT), sagittal vertical axis (SVA) and pelvic incidence minus lumbar lordosis
(PI-LL) were assessed for each patient. Clinical outcomes were evaluated using Oswestry disability Index (ODI).
Results: The mean ODI improved 32% following the corrective osteotomy of sagittal imbalance. Postoperative ODI
was significantly correlated with all preoperative radiological parameters (r=0.608, P=0.002 for PI-LL; r=0.483, P=0.01
for PT; and r=0.464, P=0.02 for SVA). ODI improvement was significantly correlated with PI-LL and SVA change (r=536,
P=0.008 and r=416, P=0.04, respectively), but not with PT change (r=247, P=0.25). The outcome was better in pedicle
subtraction osteotomy (PSO) compared to Smith-Petersen Osteotomy (SPO).
Conclusion: Surgical correction of sagittal imbalance could limit the amount of disability caused by this misalignment.
According to our results, while all the spinopelvic parameters could be used in the prediction of the outcomes of
corrective surgery of sagittal imbalance, PI-LL was the most informative parameter and more attention should be
devoted to this parameter.- انتشار مقاله: 11-07-1396
- نویسندگان: Hasan Ghandhari,Maryam Ameri Mahabadi,Farshad Nikouei,Saeed Sabbaghan,Abouzar Azizi,Alireza Mirzaei,Behrooz Givehchian
- مشاهده
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Recurrence,Sacrum,Giant Cell Tumor,Intralesional curettage
- چکیده:
- چکیده انگلیسی: There are still some debates regarding the best treatment of Giant Cell Tumor (GCT) of the sacrum. Since GCT of this location is rare, therapeutic strategies are mainly based on the treatment of GCT in other anatomic locations. The objective of this study was to evaluate the oncologic and clinical results of surgical management of sacral GCT with and without local adjuvant therapy. Medical records of 19 patients diagnosed with GCT of the sacrum, were retrospectively reviewed. Sixteen patients were treated by intralesional curettage and three patients with marginal resection. Musculoskeletal tumor society (MSTS) score was used for the evaluation of functional outcome. Prolonged pain was the most common complication after treatment. Mean Pre and post-operative pain based on visual analogue scale (VAS) was 6.1 ± 1.99 and 3.05 ± 1.64, respectively. Postoperative neurologic deficit appeared in six patients. In addition, infection occurred in five patients. One case of spinopelvic instability was also observed after surgery. At average follow up of 158.5 ± 95.9 months (25 to 316 months), recurrence was seen in eight (42.7%) out of seventeen patients treated by intralesional curettage. The size of the tumor significantly correlated with the tumor recurrence (r=0.654, P=0.001). Mean MSTS score was 74.7 ± 16.78. Those patients, in whom sacral nerve roots remained intact before and after surgery, had better functional outcome. Preservation of sacral nerve roots is associated with better functional outcome and less pain. Although an acceptable surgical outcome was observed in our cohort, the problem of local recurrence still warrants further investigations for better local control of the tumor.
- انتشار مقاله: 27-10-1395
- نویسندگان: Khodamorad Jamshidi,Abolfazl Bagherifard,Alireza Mirzaei,Mehrdad Bahrabadi
- مشاهده
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Pediatric,Osteoarticular allograft,Distal Femoral Tumor
- چکیده:
- چکیده انگلیسی: Background: There is no consensus regarding the best method of reconstruction in pediatric population following the
wide resection of malignant bone tumors. More exploration of the complications of osteoarticular reconstruction leads to
less existing controversy of this type of reconstruction, which is the main point of this article.
Methods: Long-term outcomes and complications of osteoarticular allograft reconstruction of primary distal femoral bone
sarcomas in 22 children with mean age of 10.7 years old were reviewed in this study. Musculoskeletal Tumor Society
(MSTS) scoring system was used for functional evaluation of the allografts.
Results: With an average follow-up time of 81 months, the outcomes of 16 patients with allografts at the final follow up
were evaluated. As expected, Limb length discrepancy (LLD) was observed in all patients (mean LLD= 2.73cm), which
was significantly correlated to allograft survival time (P<0.001). Degenerative joint disease (DJD) was also seen in all
patients and its grade was also significantly correlated to allograft survival time (P<0.001). The mean MSTS-score was
74% at the latest follow-up, ranging from 60% to 90%. Five and 10 year survival rate of allografts were found to be 93.3%
and 62.2%, respectively.
Conclusion: Osteoarticular allograft reconstruction could result in several complications including DJD. Despite its
considerable biologic advantage over endoprosthesis, osteoarticular allograft reconstruction is a long-lasting but still a
temporary solution before performing megaprosthesis. This allows patients to preserve their remaining physis for limb
growth and become old enough for an adult megaprosthesis.- انتشار مقاله: 28-02-1395
- نویسندگان: Khodamorad Jamshidi,Mehrdad Bahrabadi,Alireza Mirzaei
- مشاهده
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Osteoporosis,Kyphosis,Dynamic Hyperextension Brace
- چکیده:
- چکیده انگلیسی: Background: Osteoporosis and hyperkyphosis could impose a considerable financial and therapeutic burden on the affected society. Thus, new strategies to prevent or manage such complications are of significant importance. Here we evaluate the effect of ‘Dynamic Hyperextension Brace’ (DHB) on bone density, and hyperkyphosis correction.
Methods:Sixty postmenopausal women were randomly assigned to the case and control groups and followed for one year. DHB was applied in the case group according to the pre-designed protocol and the patients’ clinical and paraclinical parameters, including bone mineral density (BMD), kyphosis angle, osteoporotic fracture, and serum alkaline phosphatase (ALP) were evaluated in two groups.
Results:Despite no significant difference in basic BMD and kyphosis between the case and control groups, BMD and kyphosis were significantly improved in the DHB treated group, at the end of the study (P=0.003 and P=0.001, respectively). Serum ALP level was significantly higher in cases compared to the controls (P=0.48). The vertebral fracture rate was also lower in the case group compared to the controls.
Conclusion:The efficacy of bracing in osteoporosis and kyphosis management should be more emphasized. However, more detailed and controlled studies with more patients and a longer follow-up period is needed to adequately evaluate the long-term results of braces, including DHB.- انتشار مقاله: 29-09-1395
- نویسندگان: Hooman Shariatzadeh,Bagher Saeed Modaghegh,Alireza Mirzaei
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Otorhinolaryngology
- نوع مقاله: Journal Article
- کلمات کلیدی: Cocaine,Anti-neutrophil cytoplasmic antibody,Granulomatosis
- چکیده:
- چکیده انگلیسی: Introduction:
Cocaine-induced midline destructive lesions (CIMDL) are complications of regular nasal cocaine inhalation. CIMDL can mimic systemic diseases with positive anti-neutrophil cytoplasmic antibodies (ANCA), such as granulomatosis with polyangiitis (GPA).
Case Report:
In this article, we describe the case of a young woman who presented with nasal perforation induced by cocaine, along with positive perinuclear ANCA test (proteinase 3 antigen), misdiagnosed as limited GPA. The patient was treated with immunosuppressive therapy, which partially improved her symptoms. Admittance of cocaine use aided in the diagnosis of CIMDL. This patient was advised to stop cocaine use. Three-month follow-up revealed no further complications.
Conclusion:
Considering the seropositivity of ANCA in both CIMDL and GPA, early diagnosis of CIMDL and its differentiation from GPA is crucial, and clinicians play an important role in this regard. Lack of distinct histologic characteristics of vasculitis or unresponsiveness to standard therapeutic regimens may favor the diagnosis of CIMDL syndrome. It is crucial to recognize that these conditions may have similar presentations, so that undesired and potentially toxic treatments can be prevented.- انتشار مقاله: 03-05-1396
- نویسندگان: Alireza Mirzaei,Mozhdeh Zabihiyeganeh,Ala Haqiqi
- مشاهده