در هنگام جستجو کلمه در قسمت عنوان میتوانید کلمات مورد جستجو را با کاراکتر (-) جدا کنید.
کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Research Journal of Pharmacognosy
- نوع مقاله: Journal Article
- کلمات کلیدی: essential oil,Herbal Medicine,Giardia lamblia,Cysts,Entamoeba histolytica
- چکیده:
- چکیده انگلیسی: Background and objectives: Giardiasis and amoebiasis are two common diseases in human societies which make increasing problems for the health managing systems. In the present study, the antiparasitic activity of Allium sativum, Artemisia sieberi, Zatraria multiflora, Chenopodium botrys and Eucalyptus globulus essential oils on Giardia lamblia cysts and Entamoeba histolytica trophozoites were investigated in vitro. Methods: Giardia lamblia cysts and E. histolytica trophozoites were isolated from infected sample stools. The parasites were treated by four concentrations (0.2, 0.1, 0.01 and 0.001 µg/mL) of essential oils, separately for 30 min at 37 °C. Results: Theessential oils at the concentration of 0.1 and 0.2 µg/mL indicated appreciate parasiticidal effect (p <0.05). Eucalyptus globulus had maximum efficacy on both G. lamblia and E. histolytica with mortality rates of 79.7% and 87.6% within 30 min. Conclusion: All essential oils showed potent anti-giardiasis and anti-amoebiasis activity. Also, E. globulus with the highest efficiency could be considered as anti-protozoa medication to use an adjunct or primary therapy.
- انتشار مقاله: 26-10-1397
- نویسندگان: Mohammad Azadbakht,Aroona Chabra*,Ali Saeedi Akbarabadi,Mohammad Hossein Motazedian,Taha Monadi,Fatemeh Akbari
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Language and Translation
- نوع مقاله: Journal Article
- کلمات کلیدی: EFL Learners,perception,Academic Achievement,reading comprehension ability,Task based language teaching (TBLT)
- چکیده:
- چکیده انگلیسی: The present research was an endeavor to determine whether or not the adoption of Task-Based Language Teaching (TBLT) can be an effective means of increasing the students’ reading comprehension ability. Also, this paper explored the students' views towards the mentioned method. To fulfil the purposes of the study, a mixed method research was employed and 80 advanced EFL learners of university participated in the study that were assigned randomly to the experimental and control groups. Having instructed the two groups with the same texts but different methods of teaching during a term, the learners’ reading performance results were compared through administering a reading posttest to both groups. The researchers in the control group class followed her regular teaching practice through the conventional book-based method, but, she applied task based method in three stages in the experimental group class. The obtained data were analyzed using t-test to examine the effectiveness of TBLT method as on students’ reading performance. Moreover, the students' views of the experimental group were investigated through related questionnaire and interview. The findings revealed that the experimental group remarkably performed better than the control group. Therefore, TBLT had a significant effect on learners’ reading performance compared to traditional reading instruction. On top of that, findings of the interviews and questionnaires demonstrated the participants' satisfaction with implementing TBLT method, and also revealed that they had positive views towards it.
- انتشار مقاله: 04-04-1399
- نویسندگان: Azar Bagheri Masoudzadeh,Ali Asghar Rostami Abu Saeedi,Shahram Afraz
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Language and Translation
- نوع مقاله: Journal Article
- کلمات کلیدی: personality traits,Reading Proficiency,Multiple intelligence
- چکیده:
- چکیده انگلیسی: The present study investigated the relationship between personality traits and multiple intelligences, and learners’ reading proficiency. To this end, 384 graduate EFL students participated in the present study. Two questionnaires, namely the NEO personality inventory-revised, and McKenzie’s (1999) MI inventory as well as a sample TOFEL reading comprehension test were used to collect the data. Three regression models, backward, forward, and stepwise were used to determine prediction equations for the reading performance of EFL graduate students. Path analysis technique was employed to assess the magnitude of direct and indirect relationship of the variables. The result of the statistical analysis showed that there were only positive as well as direct relationships between interpersonal intelligence and reading proficiency, while the other intelligences such as intrapersonal, existential, naturalist, etc. would account for negative relationship with the criterion variable, reading proficiency. Agreeableness was found to be the only personality trait which had direct and negative relationship with the criterion variable. Additionally, the relationship among conscientiousness and extroversion traits as well as spatial, verbal, and mathematical intelligences with the criterion variable proved to be indirect. All the mentioned relationships between graduate EFL learners’ personality traits and multiple intelligences with their reading proficiency would lead the researchers to conclude that although various individuals have a tendency to do differently while reading in spite of the different reading preferences, readers tend to be relatively consistent in their performance.
- انتشار مقاله: 19-08-1398
- نویسندگان: Nabiollah Sadeghi,Ali Asghar Rostami Abu Saeedi,Manoochehr Jafarigohar
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of English for Academic Purposes
- نوع مقاله: Journal Article
- کلمات کلیدی: Reading Comprehension,EFL Learners,Vocabulary Retention,Multimodality
- چکیده: هدف از این تحقیق بررسی تاثیر روش چندوجهی بر درک مطلب و یادگیری لغت در بین زبان آموزان ایرانی میباشد. نمونه آماری این تحقیق را 30 زبان آموز مذکر آموزشگاه زبان انگلیسی رازی شهرستان انار تشکیل میدهد که پس از برگزاری آزمون تعیین سطح آکسفورد به صورت تصادفی به دو گروه آزمایشی و کنترل تقسیم شدند. اطلاعات جمع آوری شده با استفاده از روش آماری تجزیه و تحلیل چندمتغیره کواریانس مورد تجزیه و تحلیل قرار گرفت و نتایج مرحله کمی این تحقیق نشان داد که استفاده از روش چندوجهی بر درک مطلب و یادگیری لغت زبان آموزان تاثیر مثبت دارد. همچنین در مرحله کیفی تحقیق نظرات و عقاید شرکت کنندگان گروه آزمایشی در ارتباط با تاثیر وجه تصویر، ویدئو یا صدا در درک مطلب، وضعیت کلاسهای درسی زبان آموزان، متون چندوجهی و ارتقاء سطح زبانی آنان از طریق پرسشنامه و مصاحبه مورد بررسی قرار گرفت. نتایج مرحله کیفی تحقیق نشان داد که زبان آموزان متونی را که با تصویر همراه است به سایر متون ترجیح میدهند. همچنین نتایج این مرحله از تحقیق نشان داد زبان آموزان از تکنولوزی و متون چندوجهی برای یادگیری، سرگرمی و ارتباطات استفاده میکنند. زبان آموزان بر این باور بودند که متون چندوجهی بر پیشرفت سطح زبانی آنان تاثیر دارد و آنها استفاده از روش متون چندوجهی را بر روش متون سنتی ترجیح میدهند. همچنین زبان آموزان اعتقاد داشتند که معلمان زبان باید از روش چندوجهی برای تدریس استفاده کنند در حالی که آنها از این روش برای تدریس در کلاس درس استفاده نمیکنند.
- چکیده انگلیسی: The studies that have investigated the effects of multimodality on reading comprehension and vocabulary retention of EFL learners in the context of Iran through mixed methodology are very limited. Accordingly, this two-phase study aimed to investigate the effect multimodalities might have on reading comprehension and vocabulary retention of Iranian EFL learners. To this end, the first phase of the study included a sample of 30 male EFL learners selected through intact group sampling who were homogenized by using an OPT (Oxford Placement Test). Then they divided into experimental and control groups randomly. Passages used for experimental group were accompanied by visual images, videos, and audio tracks, while passages used for control group were the same texts without any of these. For conducting the second phase of the study, in the control group the teacher introduced the new vocabularies of each text only by their L2 definition but in the experimental group the teacher used L2 definition and image for introducing the new vocabularies. In the qualitative part of the study, an open-ended questionnaire and interview were used. By comparing pre-tests and post-tests using MANCOVA, the results showed the effectiveness of using multimodality in L2 reading classrooms and vocabulary retention of EFL learners. The analysis of the results obtained from the qualitative phase revealed that learners preferred texts to be accompanied by visual images.
- انتشار مقاله: 13-07-1398
- نویسندگان: Nahid Naderi Anari,Ali Asghar Rostami Aboo Saeedi,Mohammad Shariati
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of English for Academic Purposes
- نوع مقاله: Journal Article
- کلمات کلیدی: self-regulation,EFL Writing,feedback,Web-integrated learning
- چکیده: پژوهش حاضر،در گام نخست به بررسی تاثیر آموزش تحت وب بر روی توانایی یادگیری خودسلزماندهی در مهارت نوشتار و سپس مقایسه بازخورد تحت وب و کلاسی بر روی توانایی یادگیری خودسازماندهی در مهارت نوشتار زبان آموزان ایرانی می پردازد. جهت دسترسی به این اهداف، یک طراحی نیمه آزمایشی برای هر دو مورد انجام شد. برای رسیدن به هدف اول، یک گروه آزمایش برای آموزش تحت وب و یک گروه گواه با آموزش غیر تحت وب تشکیل گردید. این گروههای 15 نفره زبان آموز به وسیله پرسشنامه مقیاس سنجش خودسازماندهی تحصیلی، پیش آزمون و پس آزمون شدند. در مرحله دوم این تحقیق، دو گروه آزمایشی برای دو نوع بازخورد تحت وب و کلاسی وهمچنین یک گروه گواه به صورت تصادفی انتخاب شدند. نتایج تغییرات چشمگیری بین توانایی یادگیری خودسازماندهی در گروه آموزشی تحت وب با گروه آموزشی غیر تحت وب در تکالیف نوشتاری شان نشان داد. علاوه بر آن، نتایج تفاوت معناداری را در توانایی های خوسازماندهی درون گروهی در پیش آزمون نسبت به پس آزمون در دو گروه نشان داد. همچنین نتایج، تفاوت قابل توجهی بین توانایی های سه گروه دریافت کننده بازخورد تحت وب، دریافت کننده بازخورد کلاسی و گروه گواه که بازخوردی دریافت نکردند نشان نداد. هچنین نتایج تفاوت معناداری در توانایی های خود سازمان دهی درون گروهی سه گروه با توجه به نوع بازخورد دریافتی از پیش آزمون نسبت به پس آزمون نشان نداد. نتایج این تحقیق نشان می دهد که آموزش تحت وب می تواند توانایی یادگیری خودسازماندهی فراگیران زبان در مهارت نوشتار را تحت تاثیر قرار دهد. طبق نتیجه تحقیقات، برخی موارد کاربردی برای معلمان، دانش آموزان و طراحان دوره درسی ارایه شد.
- چکیده انگلیسی: Abstract
The present study intended, firstly, to investigate the effect of web-integrated instruction on self-regulated learning ability in EFL writing, and secondly, to compare and contrast the effects of paper-based feedback and web-assisted feedback on the self-regulated learning ability. To this end, a quasi-experimental design was applied for both cases. In line with the first objective, an experimental group for implementing a web-integrated instruction as treatment, and a control group with a non-web-integrated instruction were formed. Each of the mentioned groups included an average of 15 Iranian EFL students who were pre-post tested through the Academic Self-Regulated Learning Scale (ASRLS) questionnaire. In the next phase of the study, two experimental groups for the paper-based and web-assisted feedback types and a control group with no feedback were randomly taken into account. The results of the Mann-Whitney U Test indicated a statistically significant difference between the self-regulatory ability in writing tasks of the web-integrated and non-web-integrated instruction groups. The participants in the experimental group who were taught through web-integrated instruction outperformed those in the non-web-integrated group in developing their self-regulatory strategies. Moreover, comparing the self-regulatory ability of paper-based feedback, web-assisted feedback, and no feedback groups through the application of the Wilcoxon Signed-Rank Test revealed that there was not a statistically significant difference between them, and with respect to the type of feedback the groups received, no group outperformed another in developing their self-regulatory strategies. As a result, it might be concluded that web-integrated writing instruction might have a significant influence on the self-regulatory ability while feedback type does not.- انتشار مقاله: 14-08-1397
- نویسندگان: Saeed Kheiri,Hassan Soleimani,Manoochehr Jafarigohar,Ali Asghar Rostami Aboo Saeedi
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Biotechnology
- نوع مقاله: Journal Article
- کلمات کلیدی: Brucella abortus,Mutant Strains,Gene Knockout Techniques
- چکیده:
- چکیده انگلیسی: Background: Using Brucella abortus Strain 19 (S19) to control bovine brucellosis is restricted due to induce antibodies to the O-side chain of the smooth lipopolysaccharide (LPS) which may be difficult to differentiate vaccinated and infected animals. Furthermore, it is virulent for humans and can induce abortion to cattle.
Objectives: The aim of this study was to employ gene knockout B. abortus S19 for the first time to eliminate diagnostic defects and obtain the attenuated mutant strain.
Material and Methods: The wbkA gene, which is one of the LPS O-chain coding genes, was knocked out in vaccinal Brucella abortus S19. The proliferative response and immunoglobulin M production were analyzed in wbkA deletion strain-infected BALB/c mice.
Results: The loss of wbkA gene function resulted in induction of the splenocyte proliferative response in mice infected by the mutant S19 strain compare to those induced by parental S19 and RB51 strains. Moreover, wbkA mutant did not induce any IgM antibody response using the enzyme-linked immunosorbent assay.
Conclusions: As a result, the new mutant S19 strain had deficiency in its LPS O-chain structure, besides cannot induce IgM response then, reduce mistakes to discriminate between vaccinated and infected animal, and also can be considered as a new vaccine candidate.- انتشار مقاله: 22-10-1396
- نویسندگان: Bahar Nayeri Fasaei,Soulmaz Naserli,Taghi Zahrai Salehi,Alireza Saeedinia,Alimohammad Behroozikhah,Iradj Ashrafi Tamai
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Biotechnology
- نوع مقاله: Journal Article
- کلمات کلیدی: RT-PCR,Coxsackievirus B3,NASBA
- چکیده:
- چکیده انگلیسی: Enteroviruses are the causative agents of a number of diseases in humans. Group B coxsackieviruses are believed to be the most common viral agents responsible for human heart disease. Genomic data of enteroviruses has allowed developing new molecular approaches such as Nucleic Acid Sequence Based Amplification (NASBA) for detection of such viruses. In this study, coxsackievirus B3 (CVB3) was detected in virus-infected cell culture and specimens of artificially infected mice with specific primers using Reverse Transcription - Polymerase Chain Reaction (RT-PCR) and NASBA techniques. According to the results, both techniques could be used for the detection of viruses in cell culture and artificially infected animals. NASBA reaction was simpler to perform than RT-PCR. The only variable factor that had to be optimized with NASBA is KCl concentration. The optimal concentration of KCl was determined as 90 mM. Serial dilutions of 1 mg of total RNA showed that both RT-PCR and NASBA could detect the virus at 10-5 dilution. Analyses of heart and spleen samples from infected animals were positive for presence of Coxsackievirus B3 with both RT-PCR and NASBA. In conclusion, NASBA offers some advantages over RT-PCR and is a suitable alternative technique for the sensitive detection of CVB3 in contaminated samples.
- انتشار مقاله: 02-02-1394
- نویسندگان: Alireza Saeedinia,Mehdi Shamsara,Mehdi Zeinoddini,Vahid Sadeghi,Nader Maghsoudi
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Biotechnology
- نوع مقاله: Journal Article
- کلمات کلیدی: Expression,Site-directed mutagenesis,Granulocyte colony stimulating factor (G-CSF)
- چکیده:
- چکیده انگلیسی: Human granulocyte colony stimulating factor (hG-CSF) induces proliferation and differentiation of granulocyte progenitor cells. This glycoprotein is currently being used for treatment of neutropenia, in patients who have undergone bone marrow transplantation. So far, different researchers have tried to enhance hG-CSF biological activity and stability. In this study, Polymerase Chain Reaction (PCR) based site-directed mutagenesis was performed on hG-CSF cDNA. The final amplified DNA fragment was cloned into the pBluescript sk(-) plasmid and after verification of the desired mutations by sequencing, it was subcloned into the pET-21a(+) vector and expressed in Escherichia coli BL21. The mutant G-CSF product was analyzed by SDS-PAGE and Western-blot analyses. The results show that the recombinant mutant G-CSF has been cloned and expressed successfully in prokaryotic system. This research aimed to produce a new recombinant hG-CSF expected to show enhanced biological characteristics in contrast to those of the native hG-CSF. The analysis of its function and biological characteristics remain to be examined.
- انتشار مقاله: 02-02-1394
- نویسندگان: Hamed Naghoosi,Farida Behzadian,Alireza Saeedinia,Seyed Ali Ghorashi
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Biotechnology
- نوع مقاله: Journal Article
- کلمات کلیدی: Methanol,Pichia pastoris,Fed-batch culture,rhG-CSF
- چکیده:
- چکیده انگلیسی: Human granulocyte-colony stimulating factor (hG-CSF) cDNA was expressed in the methylotrophic yeast Pichia pastoris under the control of the alcohol oxidase (AOX1) promoter. An expression vector for hG-CSF secretion was constructed using vector pPIC9. Higher levels of hG-CSF was obtained using a P. pastoris Mut+ (methanol utilization fast) phenotype. The effects of environmental factors such as temperature and pH on the P. pastoris cell growth and hG-CSF production during fermentation were investigated. Cell growth and hG-CSF production were found to be optimal at 28°C and pH 6.0. A fed-batch fermentation process was also developed to obtain high cell density and higher levels of protein expression. Using a high cell density cultivation method, cell dry weight and hG-CSF concentration reached 100 g/l and 35 mg/l, respectively.
- انتشار مقاله: 19-02-1394
- نویسندگان: Ali Bahrami,Seyed Abbas Shojaosadati,Rasoul Khalilzadeh,Ali Reza Saeedinia,Ebrahim Vasheghani Farahani,Jafar Mohammadian-Mosaabadi
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Applied Language Studies
- نوع مقاله: Journal Article
- کلمات کلیدی: Evaluation,Proficiency,involvement load hypothesis,Task-Induced Involvement,Involvement Index
- چکیده:
- چکیده انگلیسی: A long-standing debate among the vocabulary researchers is the depth of processing to learn vocabulary. This paper is a quantitative research which considers a revision in the “involvement load hypothesis” proposed by Laufer and Hulstijn in 2001. It investigates the role of proficiency and evaluation in this hypothesis in order to better reveal its potential contribution to vocabulary learning. It was based on task-induced involvementthat comparesdifferent tasks in incidental vocabulary acquisition in EFL context. The participants were 66 learners fromtwo different English institutes who were classified into two major high and low proficient groups based on Nelson Proficiency Test. The participants in each group were randomly assigned to three tasks prepared to compare“moderate”, “strong”, and “no evaluation” in involvement load hypothesis.The “strong evaluation”subgroup (making original sentences) in low proficiency supported Laufer and Hulstijn’s hypothesis and yielded better retention of the target words. The study suggests that the level of proficiency and evaluation in task induced involvementneeds reconsideration. The results have implications for language teachers, materials developers, and syllabus designers.
- انتشار مقاله: 03-12-1395
- نویسندگان: Hassan Soleimani,Ali Asghar Rostami Abu Saeedi
- مشاهده