در هنگام جستجو کلمه در قسمت عنوان میتوانید کلمات مورد جستجو را با کاراکتر (-) جدا کنید.
کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Journal of Health Literacy
- نوع مقاله: Journal Article
- کلمات کلیدی: Health behavior,Health literacy,health promotion
- چکیده:
- چکیده انگلیسی: Background and objective: Health literacy is defined as ‘one’s capacity to understand and interpret the basic health information and services needed to make appropriate health decisions’. In addition, those with insufficient health literacy are less likely to understand the written and oral information presented by health specialists. Hence, insufficient health literacy is considered a global threat nowadays, the present study aimed to investigate the health literacy status among the visitors to the specialized clinics based in Kermanshah, Iran, in 2016.
Methods:The current study was a descriptive cross-sectional study. To collect the required data, the valid and reliable test of functional health literacy in adults (TOFHFLA) was employed. After data collection, the data were entered into the SPSS Statistics 16 Software. In addition, for data analysis, the descriptive statistics and the statistical tests of analysis of variance (ANOVA), Independent t-test and regression analysis were used.
Results: The mean score of health literacy among the subjects under study was 51.93 ±6.31. Further, the results revealed that the relationship between health literacy and each of the variables of education (P<0.05), Residence area (P<0.05), Household dimension (P<0.05) were significant and age (p=1.02), marital status (p=6.31), gender (p=0.5) and occupation (p=6.31) were not significant. The results revealed that the relationship between health literacy and each of the variables of age (p=1.02), marital status (p=6.31), gender (p=0.5) and occupation (p=6.31) were not significant.
Conclusion: This study showed that average health literacy in the population is estimated to be average. Recommended with changes at the macro level of society in terms of education and research increased health literacy.
Paper Type:Research Article.- انتشار مقاله: 14-09-1395
- نویسندگان: Elahe Bavandpour,Zahra Azami,Maryam Bavandpour,Omid Afsordeh,Ali Delpisheh
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی:
- انتشار مقاله: 04-08-1394
- نویسندگان: Yousef Veisani,Ali Delpisheh,Kourosh Sayehmiri,Ghobad Moradi,Jafar Hassanzadeh
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Immunology
- نوع مقاله: Journal Article
- کلمات کلیدی: Brucella abortus,Fusion protein,Human Serum Albumin,L7/L12
- چکیده:
- چکیده انگلیسی: Background: The immunogenic Brucella abortus ribosomal protein L7/L12 is a promising candidate antigen for the development of subunit vaccines against brucellosis.
Objective: This study was aimed to evaluate the protection of recombinant Human Serum Albumin (HAS)-L7/L12 fusion protein in Balb/c mice.
Methods: The amplified L7/L12 gene was cloned in pYHSA5 vector, pYHSA5-L7/L12 construct was transformed in Saccharomyces cerevisiae and the expressed protein from supernatant was purified by affinity chromatography. Balb/c mice were immunized in five groups by tHSA-L7/L12 fusion protein (group 1), Brucella abortus S19 (group 2), HSA (group 3), recombinant L7/L12 (group 4), PBS (group 5). ELISA to detect antibody production, LTT test to assess antigen specific lymphocyte response were conducted prior to virulent B. abortus strain 544 challenge two weeks after the last injection. Bacterial counts from spleens of immunized mice were done four weeks after challenge.
Results: In ELISA tests, the specific antibodies exhibited a dominance of immunoglobulin IgG1 over IgG2a. In addition, the tHSA-L7/L12 fusion protein and L7/L12 elicited a strong T-cell proliferative response upon restimulation in vitro with recombinant tHSA-L7/L12 and L7/L12, suggesting the induction of a cellular immunity response in vivo. However, there was no significant difference in proliferative response of L7/L12 and tHSA-L7/L12 fusion protein (p>0.05). The L7/L12 and tHSA-L7/L12 fusion protein vaccines could also induce significant protection against challenge with the virulent strain B. abortus 544 in Balb/c mice (p≤0.05).
Conclusion: The tHSA-L7/L12 fusion protein, similar to L7/L12 has the ability to induce antigen specific lymphocyte proliferation, stimulate humoral immunity and engender protection.- انتشار مقاله: 16-05-1395
- نویسندگان: Iraj Pakzad,Abbas Rezaee,Mohammad Javad Rasaee,Bahman Tabbaraee,Ali Delpisheh
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: Women,Pregnancy,Anemia,Meta-Analysis,Systematic review,Hemoglobin
- چکیده:
- چکیده انگلیسی: Background
The aim of this study was to determine the relationship between maternal anemia during pregnancy and pregnancy outcomes.
Materials and Methods
This systematic review was conducted in domestic (Sid, Iran.doc, Iran medex and Magiran) and international (PubMed, Science Direct, Cochrane, Medline, Web of Science, Scopus, Springer, Embase, Google scholar) databases from January 1, 1990 to April 10, 2016 with using standard key words "Pregnancy", "Pregnant women", "Hemoglobin/ haemoglobin", "Anemia/ anaemia", and "Pregnancy outcome". Relative risks (RR) and confidence intervals were extracted from each study.
Results
Overall 30 studies with a total sample size of 1,194,746 were entered into the final meta-analysis. Maternal anemia in the first trimester showed a significant relationship with low birth weight (RR: 1.28, 95% CI, 1.10 - 1.50, P<0.01), pre-term birth (RR: 1.26, 95% CI, 1.11- 1.44, P<0.01) and small for gestational age (RR: 1.12, 95% CI, 1.05 - 1.19, P<0.01`), that means maternal anemia in the first trimester raises the risk of these outcomes.
Even though, maternal anemia in the second trimester has no significant relationship with low birth weight (RR, 1.19, 95% CI, 0.65- 2.17, P>0.05) and pre-term birth (RR: 1.35, 95% CI, 0.54 - 3.24, P>0.05). Similarly, maternal anemia in the third trimester has also, no significant relationship with low birth weight (RR: 1.23, 95% CI, 0.97 - 1.55, P>0.05) and pre-term birth (RR: 1.55, 95% CI, 0.83 - 2.88, P>0.05).
Conclusion
Maternal anemia during pregnancy in the first trimester in particular can be considered as a risk factor for pregnancy outcomes and must be treated as an advance.- انتشار مقاله: 13-04-1395
- نویسندگان: Shoboo Rahmati,Ali Delpisheh,Naser Parizad,Koroush Sayehmiri
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Prostate cancer,Calcium,systematic review and meta-Analysis
- چکیده:
- چکیده انگلیسی: Background: Controversial results have been reported concerning the influence of calcium intake on prostate cancer
risk. The aim of this study was to determine any association between total calcium (in the diet and in supplements) intake
and prostate cancer. Materials and Methods: The present systematic review and meta-analysis study was carried out
following a PRISMA guidelines. Two reviewers independently using MeSH keywords searched international databases
including PubMed, Science Direct, Cochrane, EMBASE, Web of Science, CINAHL, EBSCO and search engines such
as Google Scholar. The searches were performed without any time limit until May 2016. The results were pooled
using a random effects model and homogeneity was confirmed using the Q test and I2 index. Subgroup analyses was
performed according to continents and study designs. The data were analyzed using STATA software version 3.2, with
pfinal meta-analysis. The main age range of the participants was 50 to 70 years. The relative risks (RR) for total calcium
with total prostate cancer, localized prostate cancer, and advance prostate cancer were estimated to be 1.15 (95% CI:
1.04-3.46), 1.05 (95% CI: 0.96-1.14), and 1.15 (95% CI: 0.89-1.50), respectively. Only the relationship between total
calcium and total prostate cancer was significant (P<0.05). Conclusions: High calcium intake can be considered as a
risk factor for total prostate cancer. Therefore, calcium intake might be a target for prevention.- انتشار مقاله: 04-07-1396
- نویسندگان: Shoboo Rahmati,Milad Azami,Ali Delpisheh,Mohammad Reza Hafezi Ahmadi,Koroush Sayehmiri
- مشاهده
- جایگاه : پژوهشی
- مجله: Advanced Herbal Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Medicinal plant,Experimental study,Quercetin flavonoid
- چکیده:
- چکیده انگلیسی: Background and aims: Tribulus terrestris fruit, leaf, and root have medical effects in the treatment of cancer, viral infections and prevention of cardiovascular diseases. The present study was aimed to evaluate the quercetin flavonoid levels from different parts of the Tribulus terrestris collected from different regions of Khuzestan in 2014. Methods: In this experimental study, four parts of the Tribulus terrestris including; fruits, leaves, stems and roots were collected from different regions of Khuzestan including Shushtar, Mollasani and Andimeshk. The analysis was carried out to compare the chemical profile of the different extracts of Tribulus terrorists using reverse phase HPLC with UV detector. The mobile phase that consisted of phosphoric acid buffer with pH=3 and acetonitrile was used for isocratic elution. The flow rate was adjusted to 1.0 ml/min. The detection wavelength was at 203 nm. All separations were performed at ambient temperature. Results: The results reported that the quercetin flavonoid level were highest in the Andimeshk leaves samples (69.57427 ppm). However, the Andimeshk fruits samples (4.141953 ppm) have the lowest levels of the quercetin flavonoid. Conclusion: Considering the cost effectiveness in extracting compounds from medicinal plants, it is recommended to identify the highest level of the quercetin flavonoid in each region and in each part of the plant.
- انتشار مقاله: 13-04-1394
- نویسندگان: Ali-Reza Abdali-Mashhadi,Fatemeh Direkvand-Moghadam,Majedeh Jalali,Masomeh Albobaji,Ashraf Direkvand-Moghadam,Ali Delpisheh
- مشاهده
- جایگاه : پژوهشی
- مجله: Advanced Herbal Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Medicinal plant,Experimental study,Quercetin flavonoid
- چکیده:
- چکیده انگلیسی: Background and aims: Tribulus terrestris fruit, leaf, and root have medical effects in the treatment of cancer, viral infections and prevention of cardiovascular diseases. The present study was aimed to evaluate the quercetin flavonoid levels from different parts of the Tribulus terrestris collected from different regions of Khuzestan in 2014. Methods: In this experimental study, four parts of the Tribulus terrestris including; fruits, leaves, stems and roots were collected from different regions of Khuzestan including Shushtar, Mollasani and Andimeshk. The analysis was carried out to compare the chemical profile of the different extracts of Tribulus terrorists using reverse phase HPLC with UV detector. The mobile phase that consisted of phosphoric acid buffer with pH=3 and acetonitrile was used for isocratic elution. The flow rate was adjusted to 1.0 ml/min. The detection wavelength was at 203 nm. All separations were performed at ambient temperature. Results: The results reported that the quercetin flavonoid level were highest in the Andimeshk leaves samples (69.57427 ppm). However, the Andimeshk fruits samples (4.141953 ppm) have the lowest levels of the quercetin flavonoid. Conclusion: Considering the cost effectiveness in extracting compounds from medicinal plants, it is recommended to identify the highest level of the quercetin flavonoid in each region and in each part of the plant.
- انتشار مقاله: 13-04-1394
- نویسندگان: Ali-Reza Abdali-Mashhadi,Fatemeh Direkvand-Moghadam,Majedeh Jalali,Masomeh Albobaji,Ashraf Direkvand-Moghadam,Ali Delpisheh
- مشاهده
- جایگاه : پژوهشی
- مجله: Advanced Herbal Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Gastric ulcers,Medicinal plant,HPLC,Second metabolism
- چکیده:
- چکیده انگلیسی: Background and aims: Medicinal plants are a valuable resource for flavonoids extraction. Prosopis fracta is one of the plants with medicinal properties. Prosopis fracta was found in abundance in southern regions in Iran. Coersetin is medicinal substance found in the fruit of this plant. Quercetin is used in treatment of cancer and viral infections. This study was conducted to determine the Quercetin flavonoid in Prosopis fracta samples in different regions of Khuzestan. Methods: The Prosopis fracta fruit collected from different regions of Khuzestan (Susangerd, Ahvaz, Abadan, Mollasani, Behbahan and Ramhormoz). The beads were isolated from the fruit. Shell and the flesh were dried in an Oven. The dried materials were mixed and flavonoids extracted with a suitable solvent. The extract was injected into the High Performance Liquid Chromatography (HPLC) system. Then, the compound, Quercetin quantity and standard peak in each sample have been determined. Results: Based on the results, the Susangerd samples (0.0033 mg/ml) and Abadan (0.0008 mg/ml) have maximum and minimum levels of Quercetin flavonoid, respectively. Conclusions: Quercetin flavonoid extracted from Prosopis farcta fruits of Susangerd is richer than other regions of Khuzestan province. Therefore, it is recommended to use the Prosopis fracta fruit grown in Susangerd for extraction of the Quercetin flavonoid.
- انتشار مقاله: 26-04-1393
- نویسندگان: Fatemeh Direkvand-Moghadam,Vahid Ghasemi-Seyed,Ali-Reza Abdali-Mashhadi,Amin Lotfi,Ashraf Direkvand-Moghadam,Ali Delpisheh
- مشاهده
- جایگاه : پژوهشی
- مجله: Advanced Herbal Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Gastric ulcers,Medicinal plant,HPLC,Second metabolism
- چکیده:
- چکیده انگلیسی: Background and aims: Medicinal plants are a valuable resource for flavonoids extraction. Prosopis fracta is one of the plants with medicinal properties. Prosopis fracta was found in abundance in southern regions in Iran. Coersetin is medicinal substance found in the fruit of this plant. Quercetin is used in treatment of cancer and viral infections. This study was conducted to determine the Quercetin flavonoid in Prosopis fracta samples in different regions of Khuzestan. Methods: The Prosopis fracta fruit collected from different regions of Khuzestan (Susangerd, Ahvaz, Abadan, Mollasani, Behbahan and Ramhormoz). The beads were isolated from the fruit. Shell and the flesh were dried in an Oven. The dried materials were mixed and flavonoids extracted with a suitable solvent. The extract was injected into the High Performance Liquid Chromatography (HPLC) system. Then, the compound, Quercetin quantity and standard peak in each sample have been determined. Results: Based on the results, the Susangerd samples (0.0033 mg/ml) and Abadan (0.0008 mg/ml) have maximum and minimum levels of Quercetin flavonoid, respectively. Conclusions: Quercetin flavonoid extracted from Prosopis farcta fruits of Susangerd is richer than other regions of Khuzestan province. Therefore, it is recommended to use the Prosopis fracta fruit grown in Susangerd for extraction of the Quercetin flavonoid.
- انتشار مقاله: 26-04-1393
- نویسندگان: Fatemeh Direkvand-Moghadam,Vahid Ghasemi-Seyed,Ali-Reza Abdali-Mashhadi,Amin Lotfi,Ashraf Direkvand-Moghadam,Ali Delpisheh
- مشاهده