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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی: Epidemiology,Clinical manifestations,Karoon city,Hemiscorpius lepturus
- چکیده:
- چکیده انگلیسی: Background: Hemiscorpius lepturus envenomation is one of the most important medical issues in tropical regions of Iran, especially Khuzestan Province. Due to lack of reliable data about scorpion sting in Khuzestan Province, this investigation was performed to study the clinical presentation, prognosis factors, complications and mortality rates of Hemiscorpius lepturus sting.
Methods: this study was a cross-sectional study performed at Sina Hospital, Karoon, Iran during 2011-2013. Required data such as demographic data, complications and outcomes were collected from medical records of all admitted victims of envenomation in this period and then were registered in a propriate checklist. Data were analyzed using SPSS version 16.
Results: a total of 311 victims were studied. The highest frequency of sting was in the age range of 15-24 years. Most areas of the sting were the lower extremity. Forty-two patients delayed more than 24 hours to refer to the emergency room. The most common initial symptom in victims was pain in the sting location. Complications such as hematuria, hemoglobinuria, and coagulation disorders were most morbidity occurred in patients. 6 cases died.
Conclusion: delay in referring to the hospital, the existence of hemoglobinuria, coagulation disorders and kidney failure were associated with poor prognosis in patients. It seems that patients who refer with delays and with symptoms such as hematuria, need for more medical health care.- انتشار مقاله: 23-05-1396
- نویسندگان: Bahare Hedayat,Ali Hasan Rahmani,Mohammad Matinrad,Pedram Nazari
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی: treatment,Snakebite,Manifestation,Outcome
- چکیده:
- چکیده انگلیسی: Background:Snakebite is one of the most common health problems in endemic regions such as Iran. Due to the potential life-threatening impact of snake envenomation and biodiversity of snakes, it seems that epidemiological studies are required, as the primary step to design standard and local therapeutic protocols, regarding the national and regional facilities and therapeutic needs. Methods:This investigation was conducted with a retrospective design, by studying all the records of patients affected by snakebite and hospitalized in Sina Hospital during 2006 to 2011. Epidemiological data and also the outcomes of patients (including side effects and survivals) were collected. The data were analyzed by SPSS software version 18, using descriptive statistics and Chi-Square test. P < 0.05 was considered as significant. Results:A total of287 snakebite patients were studied. 73.5% of patients were men and most of them belonged to the age group of 15-34 years. Most common complaints of patients once admitted were pain (74.6%) and edema (43.9%). 96.5% of the patients received 5-10 vials of anti-venom. The most prevalent side effect observed was coagulopathy (70.7%). A significant relationship was found between the anti-venom onset after the bite and the rate of coagulopathy occurrence (p=0.035). Three deaths had occurred in general. Conclusion:Early referral to medical centers and administration of anti-venom has been accompanied by significant improvement in outcomes, and would reduce the hematological side effects, need for administrating blood products, and probably the need for administration higher anti-venom doses.
- انتشار مقاله: 31-05-1396
- نویسندگان: Ghazal Hafezi,Ali Hasan Rahmani,Mohammad Soleymani,Pedram Nazari
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی: Poisoning,mortality,Paraquat,Disease Management,Herbicides
- چکیده:
- چکیده انگلیسی: Background: Paraquat (PQ) poisoning is highly fatal; and therefore, clinicians should be familiar with prompt approach to and poor prognostic features of this type of poisoning. Hence, in this study, clinical profile, management and outcome of a series of patients with PQ poisoning are presented.
Methods: A retrospective review of medical records of patients poisoned with PQ who were treated at Clinical Toxicology Department of Razi Hospital in Ahwaz, Iran during 2005 to 2008 was performed.
Results: Forty-two patients (66.7% men) were studied. Majority of them (83.3%) were between 15-29 years of age. Most of PQ poisonings occurred following suicidal ideation (39 patients; 92.9%). The most common on-admission clinical findings of the patients were vomiting (69%) and respiratory distress (47.6%). Activated charcoal was given to 35 patients (83.3%). N-acetyl cysteine (100 mg/kg IV stat), vitamin E (100 IU daily IV) and vitamin C (500 mg daily IV) were given to all patients. Exploratory endoscopy for plausible mucosal ulcers was carried out for 23 patients (54.8%). Pantoprazole (40 mg twice daily) was given to all patients and for 7 patients with upper gastrointestinal (GI) irritation and GI bleeding, higher doses of pantoprazole (8 mg/hour) was administered. All patients received pulse therapy with methyl prednisolone (1g daily for three days) and cyclophosphamide (15 mg/kg daily for two days). Twenty patients died. Comparing death and survival, death was significantly higher in patients with respiratory distress (100 vs. 0.0 %, P < 0.001), renal dysfunction (85.0 vs. 9.1 %, P < 0.001) and hepatic dysfunction (75.0 vs. 4.5 %, P < 0.001).
Conclusion: PQ poisoning creates a life-threatening clinical situation, which requires quick and proper treatment. Based on this research, mortality rate is greater in the presence of renal, hepatic and respiratory dysfunction.- انتشار مقاله: 09-10-1393
- نویسندگان: Ali Hasan Rahmani,Hossein Forouzandeh,Mojdeh Tadayon Khatibi
- مشاهده