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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Journal of Dental Materials and Techniques
- نوع مقاله: Journal Article
- کلمات کلیدی: adenoid cystic carcinoma,buccal mucosa,frontal metastasis
- چکیده:
- چکیده انگلیسی: Adenoid cystic carcinoma (AdCC) is a malignant neoplasm, which accounts for 5-10% of all salivary gland tumors (1). About 50% of these tumors originate from intraoral minor salivary glands usually in the hard palate (1). Three clinically obvious characteristics of AdCC include slow growth rate, perineural invasion and high incidence of distant metastasis (1). The most commonly-affected sites of distant metastasis are bone, liver and brain, followed by lungs (2). Lymph node metastases are rare; The most common sites involved by hematogenous spread are lungs (2). This is a report about a patient with a rare form of AdCC on buccal mucosa with an unusual metastasis to the frontal region after a two-year follow up.
- انتشار مقاله: 03-12-1394
- نویسندگان: Zohreh Dalirsani,Nooshin Mohtasham,Atessa Pakfetrat,Zahra Delavarian,Ala Ghazi,Seyedeh Asieh Rahimi,Zahed Anaraki
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: oral cavity,Non-hodgkin’s lymphoma,Gingival swelling
- چکیده:
- چکیده انگلیسی: Non-Hodgkin’s lymphoma is a heterogeneous malignancy originating from proliferation of lymphoid cells or their precursors. , we report a case of a 6-year-old Iranian male child admitted at the Department of Oral Medicine, School of Dentistry, Mashhad, Iran, in March 2019. The case was complaining about gingival swellings worsening for one month. Clinical and pathologic examination, complemented by biopsy and immunohistochemistry, confirmed the diagnosis of high-grade B-cell non-Hodgkin’s lymphoma. Treatment was based on chemotherapy. Intraoral involvement of lymphomas might be confused with inflammatory diseases; therefore the dentist has a crucial role in early diagnosis for appropriate management of the disease.
- انتشار مقاله: 16-03-1399
- نویسندگان: Zahra Delavarian,Atessa Pakfetrat,Zahra Badiee,Ala Ghazi,Ava Taghizadeh
- مشاهده
- جایگاه : پژوهشی
- مجله: Addiction and Health
- نوع مقاله: Journal Article
- کلمات کلیدی: Antioxidants,cotinine,Saliva
- چکیده:
- چکیده انگلیسی: Background: The cigarette compounds are associated with the increase in the incidence of oral cancer and
precancerous lesions. Salivary antioxidant system plays an important role in anti-carcinogenic capacity of
saliva. Cotinine, a nicotine metabolite, has a longer half-life in comparison with nicotine and is a suitable
marker for exposure to cigarette smoke. This study aims to measure total antioxidant capacity (TAC) and
cotinine level in saliva of smokers and non-smokers and compare salivary cotinine level and TAC in each grou.
Methods: In this cross-sectional study, 32 smokers and 34 non-smokers were recruited by consecutive
sampling from Department of Oral Medicine, School of Dentistry, Mashhad University of Medical Sciences,
Mashhad, Iran. Salivary cotinine and TAC concentrations were determined using the enzyme-linked
immunosorbent assay (ELISA) technique. For data analysis, correlation tests of Spearman, Mann-Whitney
U, and independent samples t-test were used.
Findings: A significant difference was observed between the two groups in the mean cotinine level and in the
mean TAC (P = 0.015, P = 0.027, respectively). TAC showed a weak negative correlation with the cotinine
level, but the difference was not significant (P = 0.651).
Conclusion: Antioxidants are of great importance to smokers because antioxidants are able to scavenge free
radicals found in cigarette smoke. According to the results of present study, the salivary TAC in smokers was
lower than that of non-smokers, and the salivary cotinine level in smokers was higher than non-smokers.
Therefore, smoking endangers the oral cavity health by reducing the salivary TAC. Further studies with a
higher sample size and other factors affecting the salivary TAC are needed for definitive comment.
- انتشار مقاله: 10-09-1399
- نویسندگان: Ala Ghazi,Atessa Pakfetrat,Seyed Isaac Hashemy,Farzaneh Boroomand,Abdollah Javan-Rashid
- مشاهده