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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Advanced Herbal Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Urtica dioica,Polycystic Ovary Syndrome,Liver,Necrosis,Insulin resistance
- چکیده:
- چکیده انگلیسی: Background and aims: Urtica dioica as a medicinal herb due to its anti-inflammatory, antioxidant and hypoglycemic effects, improve type 2 diabetes and decrease inflammation, fibrosis and necrosis as the signs of Nonalcoholic steatohepatitis. Polycystic Ovary Syndrome (PCOS) as the most important factor of infertility has an overlap of 30 % to 60% with liver disorders. Hence, the Urtica dioica moderator effect on liver function in PCOS rats was examined. Methods: In this experimental study 144 adult Wistar rats were divided into control, PCOS and nettle-treated groups. The group PCOS was injected subcutaneously 2 mg estradiol valerate, after 60 days and confirmed polycystic, the experimental group was injected intraperitoneally the Urtica dioica extract doses (150,250, 450 mg/kg BW). After 21 days, rats were anesthetized by chloroform; blood samples and livers were collected for histological and serological evaluation. Data were analyzed using instat3 via ANOVA one-way and p
- انتشار مقاله: 19-11-1393
- نویسندگان: Samad Zare,Mohammad Nabiuni,Akram Tayanloo,Serwa Hoseini,Latifeh Karimzadeh-Bardei
- مشاهده