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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Colorectal cancer,Dietary Inflammatory Index,Case-control
- چکیده:
- چکیده انگلیسی: Background: In Iran, colorectal cancer (CRC) is the third and fourth leading cause of cancer incidence among men
and women, respectively. Diet and inflammation have been suggested as important risk factors for CRC. We examined
the association between dietary inflammatory index (DII) scores and CRC in a case-control study conducted in Iran.
Methods: This study included 71 CRC cases and 142 controls hospitalized for acute non-neoplastic diseases. DII
scores were computed from dietary intake assessed by a previously validated food frequency questionnaire. Logistic
regression models were used to estimate odds ratios (ORs) and 95% confidence intervals (CI) adjusted for age, sex,
education, energy intake, exercise, body mass index (BMI), smoking, family history of cancer, and history of aspirin,
acetaminophen, and multivitamin use. Results: Subjects with higher DII scores (i.e., indicating a more pro-inflammatory
diet) had a higher odds of CRC with the DII being used as both a continuous variable (OR continuous = 2.20, 95% CI:
1.22-3.87) and as a categorical variable (OR tertile 3 vs tertile1 = 2.47, 95%CI: 1.10-5.55). Conclusion: These results
indicate that a pro-inflammatory diet is associated with increased odds of CRC in this Iranian population.- انتشار مقاله: 28-12-1396
- نویسندگان: Nitin Shivappa,James R Hebert,Susan E Steck,Akram Safari,Fatemeh Sedaghat,Bahram Rashidkhani
- مشاهده