در هنگام جستجو کلمه در قسمت عنوان میتوانید کلمات مورد جستجو را با کاراکتر (-) جدا کنید.
کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Journal of Kerman University of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Risk Factor,premature neonate,Retinopathy of prematurity,Low birth weight
- چکیده:
- چکیده انگلیسی: Background & Aims: Retinopathy OF prematurity (ROP) is a developmental disorder of retinal vessels in premature neonates. In recent years, because of advances in the care of neonates hospitalized in equipped Intensive care units, retinopathy of prematurity has become a major cause of blindness in those who are survived. This study assessed the incidence and severity of retinopathy and related risk factors in premature infants in Bo-Alisina and Emam Khomeini Hospitals in Sari. Methods: This was a descriptive cross-sectional study conducted for one year. All neonates hospitalized in NICU and neonatal wards of selected Hospitals with a gestational age less than 30 weeks or gestational age less than 34 weeks with unstable conditions were included for clinical and laboratory studies. Result: The incidence of ROP in 146 studied neonates was 16.4% (24 cases), of which 6 cases were of grade 1, 14 cases of grade 2 and four cases were grade 3. All four cases with grade 3 ROP were recovered with injection of intravitreal avastin or without medical therapy. Sixty six percent of patients with ROP, had a gestational age of less than 30 weeks and all of them had birth weights less than 2000grams. There was statistical correlation between the incidence of ROP and gestational age, birth weight, history of intubation, Intraventricular hemorrhage, PH <7.2, history of high or low blood pressure and fraction of inspired oxygen in newborns. But, no significant relationship was found between duration of oxygen therapy, history of sleep apnea, Resuscitation, sepsis and duration of Phototherapy with ROP. Conclusions: The incidence of retinopathy of prematurity in Bo-Alisina and Emam Khomeini Hospitals in Sari was similar to other studies. The most important risk factors were low gestational age and birth weight. Considering the risk of the disease in premature infants, ROP screening is recommended not only for prematures under 30 weeks of gestational age but also in more mature ones who have any risk factor for ROP.
- انتشار مقاله: 22-04-1395
- نویسندگان: Maryam Nakhshab,Ahmad Ahmadzadeh Amiri,Sharareh Dargahi,Roya Farhadi,Jamshid Yazdani
- مشاهده
- جایگاه : پژوهشی
- مجله: Avicenna Journal of Phytomedicine
- نوع مقاله: Journal Article
- کلمات کلیدی: lipid profile,Hibiscus sabdariffa L,Polygenic dyslipidemia,Sour tea
- چکیده:
- چکیده انگلیسی: Objective: Dyslipidemia has been considered as a major risk factor for coronary heart disease. Alternative medicine has a significant role in treatment of dyslipidemia. There are controversial findings regarding the effects of sour tea on dyslipidemia. The aim of this study was to evaluate the impact of aqueous extract of dried calyx of sour tea on polygenic dyslipidemia.
Materials and Methods: This clinical trial was done on 43 adults (30-60 years old) with polygenic dyslipidemia that were randomly assigned to the intervention and control groups. The control group was trained in lifestyle modifications at baseline. The intervention group was trained for lifestyle modifications at baseline and received two cups of sour tea daily, and both groups were followed up for 12 weeks. Lipid profile was evaluated at baseline, and six and 12 weeks following the intervention. In addition, dietary and physical activity assessed at baseline for twelve weeks.
Results: Mean concentration of total cholesterol, HDL-C and LDL-C significantly decreased by up to 9.46%, 8.33%, and 9.80%, respectively, after 12 weeks in the intervention group in comparison to their baseline values. However, LDL-C/HDL-C ratio significantly increased by up to 3.15%, following 12 weeks in the control group in comparison to their baseline values. This study showed no difference in lipid profiles between the two groups, except for HDL-C concentrations.
Conclusion: sour tea may have significant positive effects on lipid profile of polygenic dyslipidemia subjects and these effect might be attributed to its anthocyanins and inflation factor content. Therefore, sour tea intake with recommended dietary patterns and physical activity can be useful in regulation of lipid profile in patients with polygenic dyslipidemia.- انتشار مقاله: 19-04-1395
- نویسندگان: Majid Hajifaraji,Mohammad Matlabi,Farihe Ahmadzadeh-Sani Ahmadzadeh Sani,Yadollah Mehrabi,Mohammad Salem Rezaee,Homa Hajimehdipour,Abbas Hasanzadeh,Katayoun Roghani
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Efficacy,Gastric cancer,EOX,m-DCF,safety
- چکیده:
- چکیده انگلیسی: Introduction: One of the major challenges of advanced gastric cancer treatment is the lack of a standard regimen for patients. However, several clinical trials have shown that modified docetaxel, cisplatin, and 5-fluorouracil (m-DCF) and epirubicin, oxaliplatin, and capecitabine (EOX) regimens are superior to other regimens. Methods: This randomized, single-center clinical trial was performed on 40 patients with advanced gastric cancer. The first group received the m-DCF regimen as follows: docetaxel (40 mg/m2) on the first day; cisplatin (40 mg/m2) on the first and second days; and 5-fluorouracil (400 mg/m2) from the first to fourth day. The second group received the EOX regimen, including epirubicin (50 mg/m2) and oxaliplatin (130 mg/m2) i.v on the first day and capecitabine at a twice-daily dose of 625 mg/m2 p.o for 21 days. Treatment was applied every three weeks for a total of eight cycles in both groups. In each group, the overall and progression-free survival rates and toxicity were assessed. Results: A total of 40 patients were enrolled in this study (21 samples in the m-DCF group and 19 samples in the EOX group), 62.5% of whom were male. The median survival rate was 14.00 (95% CI: 11.82-16.18) months in the m-DCF group and 15.00 (95% CI: 9.56-20.43) months in the EOX group; however, differences between the groups were not significant. The progression-free survival rate was higher in the EOX group, although there was no significant difference between the two groups. Also, there was no significant difference regarding the side effects (e.g., toxicity) or need for supportive care between the groups. Conclusion: It seems that both m-DCF and EOX regimens are similar in terms of survival and toxicity and are recommended as first-line treatment for advanced gastric cancer with respect to the patient’s status.
- انتشار مقاله: 17-08-1398
- نویسندگان: Ahmad Ahmadzadeh,Seyed Saeid Seyedian,Armita Valizadeh,Mahin Soleimani,Pedram Nazari,Hossein Hamidi
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: acute myeloid leukemia,cancer-related fatigue,Aerobic exercise,walking program
- چکیده:
- چکیده انگلیسی: Background: Cancer-related Fatigue (CRF) is one of the most common complications of acute myeloid leukemia
(AML) and its related therapies. It can influence all physical and psychological aspects of the patient’s life. Also, it
is believed that exercise can improve CRF in patients with cancer. Objective: This study aimed to investigate the
effect of the walking exercise program on CRF in patients with AML undergoing chemotherapy. Methods: In this
quasi-experimental study with a pre- and post-test design, 50 patients with AML undergoing chemotherapy were
selected using a convenience sampling method at a teaching hospital in an urban area of Iran. The intervention included
daily 30 minutes of planned walking for ten days. Data was collected using a demographic data form and the Brief
Fatigue Inventory, which were filled out before the intervention, and on the fifth and tenth days of the intervention.
Findings: Statistically significant differences were reported in the reduction of CRF on the fifth day and tenth day
of the intervention (p <0.001). Conclusions: The planned walking intervention can be used as an easy and low-cost
method for reducing CRF in patients with leukemia.- انتشار مقاله: 13-02-1397
- نویسندگان: Fatemeh Gheyasi,Shahram Baraz,Amal Malehi,Ahmad Ahmadzadeh,Reza Salehi,Mojtaba Vaismoradi
- مشاهده