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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Iranian Journal of Veterinary Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Fibrin glue,3rd Degree burn,Autologus keratinocyte suspension
- چکیده:
- چکیده انگلیسی: Objective- Our point is to determine if the treatment of the 3rd degree burn wounds makes any difference if sprayed cultured autologous keratinocyte used alone or in combination with Fibrin glue. Design- Animal experimental study. Animals- 30 male Wistar rats. Procedures- Thirty male Wistar rats were selected and their keratinocytes were isolated and cultured from small skin biopsy. Rats were divided randomly into 3 equal groups and three 3rd degree burn wounds with 1 cm diameter were created on their back. Wounds were treated with normal saline (control group), Autologous keratinocyte suspension (AKS) (test group1) and AKS + Fibrin (AKS+ F) (test group2) in each rat. The wounds were photographed on selected days (0, 3, 5, 7, 10 and 14) and the percentage of wounds contraction was calculated with image analyzer. Biopsy samples were taken as well for histological studies on days 3, 7 and 14. Results-The results showed faster wound contraction for AKS and AKS+ F groups during 14 days period than control group (PConclusion and Clinical Relevance- Although it can be concluded that fibrin glue could prevent cells from dripping out of the wound and also speed up the wound contraction and extend the inflammation and fibrotic tissue formation, it did not have any effect on fastening the re-epithelialization and granulation tissue formation during 14 days.
- انتشار مقاله: 09-07-1392
- نویسندگان: Atieh Seyedian Moghaddam,Jebraiel Movaffagh,Ahmad Reza Raji,Abbas Tabatabaee Yazdi,Mahmoud Mahmoudi
- مشاهده
- جایگاه : پژوهشی
- مجله: Avicenna Journal of Phytomedicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Curcumin,Humoral immunity,Hypolipidemic Agent,Jejunum Histology
- چکیده:
- چکیده انگلیسی: Objective: Turmeric (Curcuma Longa Linn) is a medicinal plant that contains curcumin. There is a growing interest in using curcumin powder (CP) as feed additives for antioxidative and antimicrobial properties to improve human health. This study was conducted to determine the appropriate levels of CP on blood parameters, immunity, and histology of jejunum in hens.
Materials and Methods: A total of 200, 58-wk-old Hy-line hens were randomly distributed into 4 treatments (0%, 0.5%, 1.5%, and 2.5% CP or 0, 5, 15, and 25 g/kg feed, respectively) with 5 replicates (10 birds each) for 8 weeks using the completely randomized design. Blood samples were taken from 2 birds per replicate at weeks 61 and 65 to evaluate blood parameters. On weeks 63 and 65, two birds from each replicate received 0.5 ml SRBC (25%) injection in breast muscle and 7 days later, blood samples were collected to evaluate total Ig, IgG, and IgM titers in serum. Two hens were sacrificed at week 65 for the histological study of jejunum.
Results: Curcumin reduced triglycerides at 1.5% and 2.5% and cholesterol and LDL at 2.5% (p<0.05). Improvement of total Ig and IgG titers after the 1st and 2nd injections were observed. Muscle thickness in jejunum increased (p<0.05) at 1.5% curcumin and the length and surface area of villus were enhanced as well.
Conclusion: Our results demonstrate that curcumin can be used as an antioxidant at 1.5% and antilipidemic agent at 2.5% in diet.- انتشار مقاله: 21-07-1391
- نویسندگان: Javad Arshami,Mohammad Pilevar,Mohammad Aami Azghadi,Ahmad Reza Raji
- مشاهده