Evaluation of salivary immunoglobulin A level in thalassemic patients with periodontitis in comparison with thalassemic patients with healthy periodontium
Evaluation of salivary immunoglobulin A level in thalassemic patients with periodontitis in comparison with thalassemic patients with healthy periodontium
عنوان فارسی :
Evaluation of salivary immunoglobulin A level in thalassemic patients with periodontitis in comparison with thalassemic patients with healthy periodontium
عنوان انگلیسی :
Evaluation of salivary immunoglobulin A level in thalassemic patients with periodontitis in comparison with thalassemic patients with healthy periodontium
چکیده انگلیسی:
BACKGROUND AND AIM: This study was conducted to evaluate salivary immunoglobulin A (IgA) level in thalassemic patients with periodontitis in comparison to thalassemic patients with healthy periodontium.METHODS: Seventy-five patients were included in this study and were divided into three groups, group A: 25 major thalassemic patients with mild to moderate periodontitis, group B: 25 thalassemic patients with healthy periodontium, and group C: 25 systemically healthy people with normal periodontium. To measure salivary IgA levels, stimulated saliva was collected and analyzed by enzyme-linked immunosorbent assay (ELISA). The data were analyzed by t-test, ANOVA, and chi-square.RESULTS: Salivary IgA was significantly different in major thalassemia patients with periodontitis (69 µm/ml) in comparison to major thalassemia patients with healthy periodontium (81 µm/ml) (P < 0.05). The highest level of salivary IgA was observed in the systemically healthy people with normal periodontium (88 µm/ml).CONCLUSION: The levels of salivary IgA were decreased in major thalassemia patients with periodontitis and healthy periodontium in comparison to systemically healthy people with normal periodontium.
خبرنامه
برای ثبت نام در خبرنامه و دریافت خبرنامه ایمیل خود را وارد نمایید.