Comparative Analysis of Modified Liquid-Based Cytology and CytoRich Red Preparation in Assessment of Serous Effusion for Cancer Diagnosis

Comparative Analysis of Modified Liquid-Based Cytology and CytoRich Red Preparation in Assessment of Serous Effusion for Cancer Diagnosis

  • عنوان فارسی : Comparative Analysis of Modified Liquid-Based Cytology and CytoRich Red Preparation in Assessment of Serous Effusion for Cancer Diagnosis
  • عنوان انگلیسی : Comparative Analysis of Modified Liquid-Based Cytology and CytoRich Red Preparation in Assessment of Serous Effusion for Cancer Diagnosis
  • مجله : Asian Pacific Journal of Cancer Prevention
  • issn(مجله) : 1513-7368
  • نوع مقاله: Journal Article
  • زبان: انگلیسی
  • نوع انتشار: مقاله چاپ شده
  • انتشار مقاله: 11-08-1396
  • شماره(No): 6
  • جایگاه : پژوهشی
  • دوره: 19
  • شماره صفحه: 1571,1575
  • تعداد نویسندگان: 6
  • doI: 10.22034/APJCP.2018.19.6.1571
  • مقاله مستخرج از:
  • نویسندگان: Porntip Jangsiriwitayakorn , Natcha Patarapadungkit , Surachat Chaiwiriyakul , Ratchaneekorn Thongbor , Phannatorn Sirivech , Luxkana Nititarakul ,
  • چکیده:
  • چکیده انگلیسی: Objective: We aimed to compare the cytomorphological diagnosis in serous effusion and quality of background
    between modified liquid-based cytology (modified-LBC) and CytoRich Red (CRR) preservative. Methods: We used
    an experimental study design: 110 fresh serous effusions were received from 50 cases negative for malignant effusions
    and 60 cases positive for malignant effusions. All fresh serous effusions were processed using both the CRR solution
    and the modified-LBC preparation. Blind sample slides were interpreted for cytomorphological diagnosis and the
    quality of background by 2 cytotechnologists. Result: All cases had the same diagnosis irrespective of the method.
    There was no statistically significant difference in the cytological diagnosis between the CRR and modified-LBC
    preparations (p>0.999). The quality of the background smear for the CRR preparation was clean (54%), moderate in
    42%, and poor in 4%. By comparison, the modified-LBC preparation was clean in 46%, moderate in 47%, and poor in
    7%. The difference between the quality of background smears between the two methods was not statistically significant
    (p= 0.527). Conclusion: There was no statistically significant difference in the diagnosis or quality of background
    between CRR and modified-LBC preparations. The serous effusion specimen prepared by modified-LBC solution was
    less expensive than CRR. The modified-LBC could be an alternative preparation when commercial preparations are
    too expensive.
Comparative Analysis of Modified Liquid-Based Cytology and CytoRich Red Preparation in Assessment of Serous Effusion for Cancer Diagnosis

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