چکیده انگلیسی:
The primary aim of this study was to investigate the status of RANKL6-7 gene polymorphism in patients with chronic (mild, moderate, severe) and aggressive periodontitis as well as healthy controls. We examined 80 patients for the RANKL6-7 polymorphisms (rs1054016 and rs9567000). Polymorphism was determined by polymerase chain reaction (PCR) followed by direct sequencing. No statistically significant association was found between the polymorphism in the RANKL 7 gene and periodontal disease (P<0.55). There was also no polymorphic allele observed in RANKL 6 gene of the study population. We found no association between the studied RANKL polymorphisms and chronic/aggressive periodontitis.
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