Facile ionic liquid-mediated, multi component synthesis of dihydro-1H-furo[2,3-c]pyrazoles

عنوان فارسی : Facile ionic liquid-mediated, multi component synthesis of dihydro-1H-furo[2,3-c]pyrazoles
عنوان انگلیسی : Facile ionic liquid-mediated, multi component synthesis of dihydro-1H-furo[2,3-c]pyrazoles
مجله : Asian Journal of Green Chemistry
issn(مجله) : 2588-5839
نوع مقاله: Journal Article
زبان: انگلیسی
نوع انتشار: مقاله چاپ شده
انتشار مقاله: 11-05-1397
شماره(No): 3
جایگاه : پژوهشی
دوره: 3
شماره صفحه: 306,321
تعداد نویسندگان: 3
doI: 10.22034/ajgc.2018.142927.1090
مقاله مستخرج از:
نویسندگان: Venkata Swamy Tangeti , Venkata Swamy Tangeti , Venkata Swamy Tangeti ,
چکیده:
چکیده انگلیسی: A facile, convenient, efficient, and high-yielding diastereoselective synthesis of a novel fused dihydro-1H-furo[2,3-c]pyrazole by a one-pot four-component reaction of β-keto ester, hydrazine, aromatic aldehyde and pyridinium salt in the presence of [bmIm]OH ionic liquid medium provided with excellent yields. Three new bonds (two C‒C and one C‒O), and two stereo centres are generated in a single operation. Low cost, short reaction time, excellent yield, operational simplicity, and more importantly the purification of the compounds by a non-chromatographic method make this process very significant for academic research and practical applications.

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