چکیده انگلیسی:
Background: The first case of Coronavirus Disease (COVID-19) was reported in Iran on February 19, 2020. This study aimed to assess the characteristics and reproduction number (R) of COVID-19 in Markazi province in Iran. Methods: This is a cross-sectional study. Confirmed cases (N=2430) in the regions covered by Arak University of Medical Sciences from Feb 20 to Aug 26, 2020 were enrolled in the study. The included variables were clinical and demographic characteristics of COVID-19 patients. The case fatality rate (CFR), incidence rates, and R were estimated based on the daily reported data. For estimating R, generation time was assumed on multi scenarios. R was estimated by R0-package. Moreover, Chi square test was applied. All the analyses were performed in STATA, Excel, ArcMap and R. A p-value less than 0.05 was considered as statistically significant. Results: The mean age of the participants was 51.78±20.58 years, and 206(8.50%) cases were among healthcare workers. Among the patients, 499 (20.50%) had a history of cardiovascular diseases and 337(13.90%) diabetes type 2. The most prevalent symptoms were cough 1347(55.40%), fever 1233(50.70%), and dyspnea 960 (39.50%). The highest incidence rate of COVID-19 in the study area (Delijan) was 575.35 per 100,000 persons. CFR was 205(8.40%). At the end of the study period, R was calculated as 1.04 (CI 95%: 1.00, 1.08) in all districts of Arak University of Medical Sciences. The highest R (1.08, 95% CI: 1.06, 1.10) was observed in Farahan. Conclusion: As R is slightly high, the risk of epidemic has reduced gradually. However, observing social distance and related guidelines are still recommended.
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